Therapeutic Effect and Mechanism of Papaver somniferum on Myopia and Complete Chloroplast Genome Analysis

Myopia is a global medical and social problem and is one of the main eye diseases leading to vision loss and blindness. Papaver somniferum is an important medicinal plant with analgesic, antitussive, and anti-asthmatic effects. In this research, the therapeutic effect and mechanism of Papaver somniferum on myopia was evaluated. After ingredient extraction, the relative expression levels of MMP-1 and MMP-2 in the sclerocytes were determined through real-time RT-PCR. In addition, inflammatory cytokines secreted to the tears were assessed via ELISA assay. Finally, the chloroplast gene sequence of Papaver somniferum was sorted, and the neighbor joining phylogenetic analysis was conducted.

Automated summary

This research evaluated the therapeutic effect and mechanism of Papaver somniferum on myopia, finding that it regulates the expression levels of MMP-1 and MMP-2 in sclerocytes and inflammatory cytokines in tears.