4.7 Article

An active tumor-targeting organic photochemotherapy agent with naproxen for enhanced cancer therapy

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Chemistry, Multidisciplinary

Targeted Engineering of Medicinal Chemistry for Cancer Therapy: Recent Advances and Perspectives

Weihua Chen et al.

Summary: This review highlights the main drawbacks of current anticancer drugs and the urgency to improve targeting efficacy. It summarizes current targeting strategies and offers guidelines for structure optimization to obtain effective targeting drugs. Additionally, it presents viewpoints on crucial problems and potential challenges in future research on targeted cancer therapy.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Article Chemistry, Multidisciplinary

Second Near-Infrared Photothermal Semiconducting Polymer Nanoadjuvant for Enhanced Cancer Immunotherapy

Jingchao Li et al.

Summary: This study introduces a novel semiconducting polymer nanoadjuvant for second NIR-II photothermal immunotherapy, which effectively inhibits tumor growth and eliminates metastasis through a combination of photothermal conversion and TLR agonist release.

ADVANCED MATERIALS (2021)

Article Chemistry, Multidisciplinary

Sequential Modulations of Tumor Vasculature and Stromal Barriers Augment the Active Targeting Efficacy of Antibody-Modified Nanophotosensitizer in Desmoplastic Ovarian Carcinoma

Yue Yan et al.

Summary: The study highlights the importance of regulating the tumor microenvironment to enhance the therapeutic efficacy of active-targeted nanophotosensitizers, with normalization of tumor vasculature and photoablation of stromal cells improving tumor accumulation and cancer cell accessibility of the nanoparticles. This sequential regulation strategy significantly enhances the antitumor efficacy of active-targeted nanoparticles, providing a basis for accelerating their clinical translation.

ADVANCED SCIENCE (2021)

Review Cell Biology

Inflammatory Cytokines in Cancer: Comprehensive Understanding and Clinical Progress in Gene Therapy

Tianxia Lan et al.

Summary: Recent research has shown that the crucial components of cancer-related inflammation interact in a coordinated system to influence cancer development, offering new insights for potential anticancer therapies. Gene therapy targeting inflammatory cytokines is considered the most efficient approach for modulating the inflammatory microenvironment in cancer therapy. This manuscript provides a comprehensive review of the relationship between inflammation and cancer development, focusing specifically on inflammatory cytokines, and summarizes clinical trials for gene therapy targeting inflammatory cytokines in cancer treatment, as well as future perspectives on new gene-editing technology and novel gene delivery systems.
Article Chemistry, Multidisciplinary

Intracellular Bottom-up Synthesis of Ultrasmall CuS Nanodots in Cancer Cells for Simultaneous Photothermal Therapy and COX-2 Inactivation

Liandong Feng et al.

Summary: A new treatment strategy involving Cu-meloxicam complexes encapsulated by human serum albumin for intracellular bottom-up synthesis of CuS nanodots has been developed, which effectively eliminates tumors and inhibits inflammation induced by photothermal damage. The therapy demonstrates promising results for precise cancer treatment.

ADVANCED FUNCTIONAL MATERIALS (2021)

Article Chemistry, Multidisciplinary

Engineering a Hydrogen-Sulfide-Based Nanomodulator to Normalize Hyperactive Photothermal Immunogenicity for Combination Cancer Therapy

Jie Li et al.

Summary: The gas-modulated photothermal immunogenicity strategy, which integrates a polysulfide-based hydrogen sulfide donor with a conjugated polymer, shows great potential in inhibiting tumor growth and limiting inflammation.

ADVANCED MATERIALS (2021)

Article Chemistry, Multidisciplinary

A Protein-Binding Molecular Photothermal Agent for Tumor Ablation

Mingwan Shi et al.

Summary: The study employed a protein-binding strategy to design a molecular photothermal agent, which significantly enhanced the therapeutic effect of photothermal therapy.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Review Chemistry, Multidisciplinary

Stimuli-activated molecular photothermal agents for cancer therapy

Kaiye Wang et al.

Summary: This review summarizes the recent progress in stimuli-activated molecular photothermal agents (MPTAs) research, including different stimuli, features and challenges, aiming to encourage readers to design and synthesize more efficient MPTAs.

CHEMICAL COMMUNICATIONS (2021)

Article Chemistry, Multidisciplinary

An efficient strategy for cancer therapy using a tumor- and lysosome-targeted organic photothermal agent

Hongyu Wang et al.

Summary: The dual-targeted organic photothermal agent developed is capable of targeting tumor cells and lysosomes, showing low cytotoxicity, good biological compatibility, and tumor inhibitory effects in both in vitro and in vivo experiments.

NANOSCALE (2021)

Article Chemistry, Multidisciplinary

A pH-responsive ultrathin Cu-based nanoplatform for specific photothermal and chemodynamic synergistic therapy

Tingting Hu et al.

Summary: This study has developed a novel tumor therapy nanoplatform by integrating acid-enhanced photothermal therapy and pH-responsive chemodynamic therapy, which almost eliminates tumor tissue in vivo with low-dose drug injection.

CHEMICAL SCIENCE (2021)

Review Oncology

Clinical development and potential of photothermal and photodynamic therapies for cancer

Xingshu Li et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2020)

Article Chemistry, Multidisciplinary

Dual-targeted photothermal agents for enhanced cancer therapy

Kaiye Wang et al.

CHEMICAL SCIENCE (2020)

Review Chemistry, Multidisciplinary

Photothermal therapy and photoacoustic imaging via nanotheranostics in fighting cancer

Yijing Liu et al.

CHEMICAL SOCIETY REVIEWS (2019)

Article Chemistry, Multidisciplinary

A Dual-Targeted Organic Photothermal Agent for Enhanced Photothermal Therapy

Hongyu Wang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

Article Chemistry, Multidisciplinary

An anti-inflammatory nanoagent for tumor-targeted photothermal therapy

Wei Pan et al.

CHEMICAL COMMUNICATIONS (2019)

Article Chemistry, Analytical

Small Molecule Interferences in Resazurin and MU-Based Metabolic Assays in the Absence of Cells

Bella H. Neufeld et al.

ANALYTICAL CHEMISTRY (2018)

Article Chemistry, Multidisciplinary

A Size-Reducible Nanodrug with an Aggregation-Enhanced Photodynamic Effect for Deep Chemo-Photodynamic Therapy

Chendong Ji et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

Article Chemistry, Medicinal

Nonsteroidal Anti-Inflammatory Therapy: A Journey Toward Safety

Catarina Pereira-Leite et al.

MEDICINAL RESEARCH REVIEWS (2017)

Article Biochemical Research Methods

Cellometer image cytometry as a complementary tool to flow cytometry for verifying gated cell populations

Dmitry Kuksin et al.

ANALYTICAL BIOCHEMISTRY (2016)

Article Cell Biology

Inflammation and cancer: tissue regeneration gone awry

Marina Pesic et al.

CURRENT OPINION IN CELL BIOLOGY (2016)

Review Medicine, General & Internal

Inflammation and cancer: back to Virchow?

F Balkwill et al.

LANCET (2001)