4.7 Article

An active tumor-targeting organic photochemotherapy agent with naproxen for enhanced cancer therapy

期刊

CHEMICAL COMMUNICATIONS
卷 58, 期 62, 页码 8682-8685

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ROYAL SOC CHEMISTRY
DOI: 10.1039/d2cc01729f

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资金

  1. National Natural Science Foundation of China [22106093, 21874086]

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This new active tumor-targeting organic photochemotherapy agent combines an organic photothermal material with a naproxen prodrug to precisely kill cancer cells and suppress inflammatory responses. In vitro and in vivo experiments have shown its low cytotoxicity and excellent tumor inhibitory effect.
An active tumor-targeting organic photochemotherapy agent via the combination of a an organic photothermal material and a naproxen prodrug was developed to precisely kill cancer cells and suppress the inflammatory response induced by cell necrosis; in vitro, and in vivo experiments illustrated its low cytotoxicity and excellent tumor inhibitory effect.

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