相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Detecting cell-type-specific allelic expression imbalance by integrative analysis of bulk and single-cell RNA sequencing data
Jiaxin Fan et al.
PLOS GENETICS (2021)
Cholesterol Auxotrophy as a Targetable Vulnerability in Clear Cell Renal Cell Carcinoma
Romain Riscal et al.
CANCER DISCOVERY (2021)
Detection of quantitative trait loci from RNA-seq data with or without genotypes using BaseQTL
Elena Vigorito et al.
NATURE COMPUTATIONAL SCIENCE (2021)
Interactions between a Polygenic Risk Score and Non-genetic Risk Factors in Young-Onset Breast Cancer
M. Shi et al.
SCIENTIFIC REPORTS (2020)
The GTEx Consortium atlas of genetic regulatory effects across human tissues
Francois Aguet et al.
SCIENCE (2020)
A vast resource of allelic expression data spanning human tissues
Stephane E. Castel et al.
GENOME BIOLOGY (2020)
Regulation of ERAP1 and ERAP2 genes and their disfunction in human cancer
Mirco Compagnone et al.
HUMAN IMMUNOLOGY (2019)
A transcriptome-wide association study of high-grade serous epithelial ovarian cancer identifies new susceptibility genes and splice variants
Alexander Gusev et al.
NATURE GENETICS (2019)
Molecular and pharmacological modulators of the tumor immune contexture revealed by deconvolution of RNA-seq data
Francesca Finotello et al.
GENOME MEDICINE (2019)
Dynamic genetic regulation of gene expression during cellular differentiation
B. J. Strober et al.
SCIENCE (2019)
Using Transcriptomic Hidden Variables to Infer Context-Specific Genotype Effects in the Brain
Bernard Ng et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2019)
Discovery of common and rare genetic risk variants for colorectal cancer
Jeroen R. Huyghe et al.
NATURE GENETICS (2019)
Quantifying tumor-infiltrating immune cells from transcriptomics data
Francesca Finotello et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2018)
Mixed-model association for biobank-scale datasets
Po-Ru Loh et al.
NATURE GENETICS (2018)
A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer
Lang Wu et al.
NATURE GENETICS (2018)
Using an atlas of gene regulation across 44 human tissues to inform complex disease- and trait-associated variation
Eric R. Gamazon et al.
NATURE GENETICS (2018)
Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci
Fredrick R. Schumacher et al.
NATURE GENETICS (2018)
Large-scale transcriptome-wide association study identifies new prostate cancer risk regions
Nicholas Mancuso et al.
NATURE COMMUNICATIONS (2018)
Impact of Genetic Polymorphisms on Human Immune Cell Gene Expression
Benjamin J. Schmiedel et al.
CELL (2018)
Cell-type-specific eQTL of primary melanocytes facilitates identification of melanoma susceptibility genes
Tongwu Zhang et al.
GENOME RESEARCH (2018)
Comprehensive functional genomic resource and integrative model for the human brain
Daifeng Wang et al.
SCIENCE (2018)
The chromatin accessibility landscape of primary human cancers
M. Ryan Corces et al.
SCIENCE (2018)
Cancer expression quantitative trait loci (eQTLs) can be determined from heterogeneous tumor gene expression data by modeling variation in tumor purity
Paul Geeleher et al.
GENOME BIOLOGY (2018)
Transcriptome Deconvolution of Heterogeneous Tumor Samples with Immune Infiltration
Zeya Wang et al.
ISCIENCE (2018)
Identification of context-dependent expression quantitative trait loci in whole blood
Dania V. Zhernakova et al.
NATURE GENETICS (2017)
Quantifying the regulatory effect size of cis-acting genetic variation using allelic fold change
Pejman Mohammadi et al.
GENOME RESEARCH (2017)
Association analysis identifies 65 new breast cancer risk loci
Kyriaki Michailidou et al.
NATURE (2017)
Elements of cancer immunity and the cancer-immune set point
Daniel S. Chen et al.
NATURE (2017)
Genetic effects on gene expression across human tissues
Francois Aguet et al.
NATURE (2017)
Linkage disequilibrium-dependent architecture of human complex traits shows action of negative selection
Steven Gazal et al.
NATURE GENETICS (2017)
Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors
Beatrice S. Melin et al.
NATURE GENETICS (2017)
Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer
Catherine M. Phelan et al.
NATURE GENETICS (2017)
Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes
James D. McKay et al.
NATURE GENETICS (2017)
Allele-specific expression reveals interactions between genetic variation and environment
David A. Knowles et al.
NATURE METHODS (2017)
Genome-wide association study identifies multiple risk loci for renal cell carcinoma
Ghislaine Scelo et al.
NATURE COMMUNICATIONS (2017)
Pan-cancer Immunogenomic Analyses Reveal Genotype-Immunophenotype Relationships and Predictors of Response to Checkpoint Blockade
Pornpimol Charoentong et al.
CELL REPORTS (2017)
New strategies for cancer immunotherapy: targeting regulatory T cells
Francesca Finotello et al.
GENOME MEDICINE (2017)
Automated deconvolution of structured mixtures from heterogeneous tumor genomic data
Theodore Roman et al.
PLOS COMPUTATIONAL BIOLOGY (2017)
Simultaneous enumeration of cancer and immune cell types from bulk tumor gene expression data
Julien Racle et al.
ELIFE (2017)
xCell: digitally portraying the tissue cellular heterogeneity landscape
Dvir Aran et al.
GENOME BIOLOGY (2017)
The Cancer Genomics Cloud: Collaborative, Reproducible, and Democratized-A New Paradigm in Large-Scale Computational Research
Jessica W. Lau et al.
CANCER RESEARCH (2017)
Fine-mapping cellular QTLs with RASQUAL and ATAC-seq
Natsuhiko Kumasaka et al.
NATURE GENETICS (2016)
Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells
Lu Chen et al.
CELL (2016)
Genetic Ancestry and Natural Selection Drive Population Differences in Immune Responses to Pathogens
Yohann Nedelec et al.
CELL (2016)
High-throughput allele-specific expression across 250 environmental conditions
Gregory A. Moyerbrailean et al.
GENOME RESEARCH (2016)
Estimating the population abundance of tissue-infiltrating immune and stromal cell populations using gene expression
Etienne Becht et al.
GENOME BIOLOGY (2016)
Comprehensive analyses of tumor immunity: implications for cancer immunotherapy
Bo Li et al.
GENOME BIOLOGY (2016)
The prognostic landscape of genes and infiltrating immune cells across human cancers
Andrew J. Gentles et al.
NATURE MEDICINE (2015)
WASP: allele-specific software for robust molecular quantitative trait locus discovery
Bryce van de Geijn et al.
NATURE METHODS (2015)
The role of regulatory variation in complex traits and disease
Frank W. Albert et al.
NATURE REVIEWS GENETICS (2015)
The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans
Kristin G. Ardlie et al.
SCIENCE (2015)
Systematic pan-cancer analysis of tumour purity
Dvir Aran et al.
NATURE COMMUNICATIONS (2015)
Cell Specific eQTL Analysis without Sorting Cells
Harm-Jan Westra et al.
PLOS GENETICS (2015)
Allele-specific expression and eQTL analysis in mouse adipose tissue
Yehudit Hasin-Brumshtein et al.
BMC GENOMICS (2014)
Allelic Expression of Deleterious Protein-Coding Variants across Human Tissues
Kimberly R. Kukurba et al.
PLOS GENETICS (2014)
Genetic Mapping with Multiple Levels of Phenotypic Information Reveals Determinants of Lymphocyte Glucocorticoid Sensitivity
Joseph C. Maranville et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2013)
Oncology Meets Immunology: The Cancer-Immunity Cycle
Daniel S. Chen et al.
IMMUNITY (2013)
A statin-dependent QTL for GATM expression is associated with statin-induced myopathy
Lara M. Mangravite et al.
NATURE (2013)
Identification of Genetic Variants That Affect Histone Modifications in Human Cells
Graham McVicker et al.
SCIENCE (2013)
Basic principles of tumor-associated regulatory T cell biology
Peter A. Savage et al.
TRENDS IN IMMUNOLOGY (2013)
A Statistical Framework for eQTL Mapping Using RNA-seq Data
Wei Sun
BIOMETRICS (2012)
Effects of sequence variation on differential allelic transcription factor occupancy and gene expression
Timothy E. Reddy et al.
GENOME RESEARCH (2012)
Breast cancer risk-associated SNPs modulate the affinity of chromatin for FOXA1 and alter gene expression
Richard Cowper-Sal-lari et al.
NATURE GENETICS (2012)
A powerful and flexible statistical framework for testing hypotheses of allele-specific gene expression from RNA-seq data
Daniel A. Skelly et al.
GENOME RESEARCH (2011)
Interactions between Glucocorticoid Treatment and Cis-Regulatory Polymorphisms Contribute to Cellular Response Phenotypes
Joseph C. Maranville et al.
PLOS GENETICS (2011)
Genome-wide allele-specific analysis: insights into regulatory variation
Tomi Pastinen
NATURE REVIEWS GENETICS (2010)
Variation in Transcription Factor Binding Among Humans
Maya Kasowski et al.
SCIENCE (2010)
Heritable Individual-Specific and Allele-Specific Chromatin Signatures in Humans
Ryan McDaniell et al.
SCIENCE (2010)
Abundant Quantitative Trait Loci Exist for DNA Methylation and Gene Expression in Human Brain
J. Raphael Gibbs et al.
PLOS GENETICS (2010)
Altered expression of endoplasmic reticulum aminopeptidases ERAP1 and ERAP2 in transformed non-lymphoid human tissues
Doriana Fruci et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2008)
A genome-wide association study identifies protein quantitative trait loci (pQTLs)
David Melzer et al.
PLOS GENETICS (2008)
Statistical significance for genomewide studies
JD Storey et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)