期刊
NEW JOURNAL OF CHEMISTRY
卷 46, 期 30, 页码 14324-14327出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/d2nj02908a
关键词
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资金
- National Natural Science Foundation of China [21875020, 22075024]
A novel synthesis method for heterocyclic fused pyridazine di-N-oxides (triazole, furoxan, furazan) was described. The use of PIDA as a mild oxidant allowed for efficient synthesis of these motifs, solving the issues of harsh conditions and cumbersome manipulation in existing methods. Furthermore, the first synthesis of triazole fused pyridazine di-N-oxide provides a valuable building block for the preparation of biologically relevant molecules and energetic compounds.
A novel approach for the synthesis of heterocyclic (triazole, furoxan, furazan) fused pyridazine di-N-oxides was described. The use of PIDA as a mild oxidant enabled the synthesis of these motifs in an efficient manner, which solved the issues of harsh conditions and cumbersome manipulation of existing methods. Moreover, the first synthesis of triazole fused pyridazine di-N-oxide provides a usable building block for the preparation of highly biologically relevant molecules as well as energetic compounds.
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