期刊
INTERNATIONAL IMMUNOLOGY
卷 34, 期 8, 页码 399-407出版社
OXFORD UNIV PRESS
DOI: 10.1093/intimm/dxac029
关键词
granulocytes; immunity; inflammation; steady state
类别
资金
- Cumming School of Medicine Graduate Scholarship
- Natural Sciences and Engineering Research Council of Canada (NSERC) Vanier Graduate Scholarship
- Canadian Institutes of Health Research
- NSERC
Neutrophils, previously believed to be short-lived killer cells, are now recognized to have more complex functions, including tissue homeostasis and repair.
Neutrophils are the most abundant innate immune cell and are equipped with highly destructive molecular cargo. As such, these cells were long thought to be short-lived killer cells that unleash their full cytotoxic programs on pathogens following infection and on host bystander cells after sterile injury. However, this view of neutrophils is overly simplistic and as a result is outdated. Numerous studies now collectively highlight neutrophils as far more complex and having a host of homeostatic and tissue-reparative functions. In this review, we summarize these underappreciated roles across organs and injury models.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据