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Review
Biochemistry & Molecular Biology
Xueli Tian et al.
Summary: Lung cancer is the most deadly cancer worldwide, with non-small cell lung cancer (NSCLC) being the main type and EGFR as a key driver gene. Despite the effectiveness of EGFR-tyrosine kinase inhibitors in targeted therapy, acquired resistance remains a significant challenge, prompting the exploration of combination treatment options.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
(2022)
Review
Oncology
Sharon Harrison et al.
Summary: This review explores the racial disparities in lung cancer treatment and the factors contributing to these disparities, including social determinants of health, differences in guideline-concordant therapy, molecular testing, and clinical trial involvement.
CURRENT ONCOLOGY REPORTS
(2022)
Article
Oncology
Ling Peng et al.
Summary: This study conducted a meta-analysis to explore the association between the use of bevacizumab and the risk of infections in non-small-cell lung cancer (NSCLC) patients. The results indicate that bevacizumab treatment is not significantly associated with a higher risk of infections in NSCLC patients, providing reassurance regarding the safety of bevacizumab in this population.
ONCOLOGY RESEARCH AND TREATMENT
(2022)
Article
Public, Environmental & Occupational Health
Xiang Chen et al.
Summary: This study analyzed the epidemiological trends of lung cancer over the past 30 years and found that the incidence of lung cancer has decreased, while the prevalence and years lived with disability (YLDs) have increased. The prevalence of lung cancer is higher in males and increases with age. The increase in incidence is mainly due to population aging. There is a negative correlation between YLDs and the human development index and ASR.
Article
Health Care Sciences & Services
Silvia Minozzi et al.
Summary: The study assessed the inter-rater reliability of the revised RoB2 tool and proposed an implementation document specific to the tool to improve reliability. Results showed an increase in agreement and a decrease in the average time to apply the tool after the adoption of the ID.
JOURNAL OF CLINICAL EPIDEMIOLOGY
(2022)
Article
Cell Biology
Shaochuan Liu et al.
Summary: This study reveals the positive regulatory role of CD4(+) T cells on the function of CD3(+)CD56(+) T and CD3(+)CD8(+) T cells in CIK therapy, suggesting that CD4(+) T cells can induce the phosphorylation of the AKT pathway by secreting IL-17A to restore the function of specific T cells, which is crucial for enhancing the efficacy of CIK therapy.
CELL DEATH & DISEASE
(2022)
Review
Oncology
Lin Zhang et al.
Summary: This study provides an overview of the clinical trials on Sintilimab for non-small cell lung cancer (NSCLC) conducted in China, showing its effectiveness and tolerability, but further research is needed.
BIOMARKER RESEARCH
(2022)
Article
Public, Environmental & Occupational Health
Wenjing Ye et al.
Summary: The study revealed an increasing trend in lung cancer death rates in PNA from 1973 to 2019, primarily attributed to demographic factors. This research can aid in designing future prevention plans for similar cities.
JMIR PUBLIC HEALTH AND SURVEILLANCE
(2022)
Article
Psychiatry
Xue-Mei Wang et al.
Summary: The objective of this study was to verify the psychometric characteristics of the Chinese Adaptation of self-report HAMD-6 and show that it has good reliability and validity among the Chinese population.
ASIAN JOURNAL OF PSYCHIATRY
(2022)
Article
Oncology
Han-Bing Lu et al.
Summary: This study examined the effects of the active cycle of breathing technique (ACBT) on perioperative outcomes in patients with lung cancer. The results showed that ACBT significantly improved dyspnea, anxiety, depression, and postoperative pulmonary complications for patients at discharge.
CLINICAL JOURNAL OF ONCOLOGY NURSING
(2022)
Article
Oncology
Hyuna Sung et al.
Summary: The global cancer burden in 2020 saw an estimated 19.3 million new cancer cases and almost 10.0 million cancer deaths. Female breast cancer surpassed lung cancer as the most commonly diagnosed cancer, while lung cancer remained the leading cause of cancer death. These trends are expected to rise in 2040, with transitioning countries experiencing a larger increase compared to transitioned countries due to demographic changes and risk factors associated with globalization and a growing economy. Efforts to improve cancer prevention measures and provision of cancer care in transitioning countries will be crucial for global cancer control.
CA-A CANCER JOURNAL FOR CLINICIANS
(2021)
Review
Medicine, General & Internal
Han Li et al.
Summary: This systematic review and meta-analysis explored the efficacy and safety of acupuncture and auricular acupressure for relieving cancer related fatigue (CRF) in lung cancer patients during chemotherapy, indicating that the combined use of both may be effective.
Review
Oncology
Maria Sereno et al.
Summary: Recent studies have explored different combinations of immunotherapy and chemotherapy to improve survival outcomes in advanced non-small cell lung cancer. Research is investigating whether combining different immunologic antitumoral mechanisms of action, such as anti-PD-1/PD-L1 and anti-CTLA-4, or anti-PD-L1 and anti-TIGIT, can improve efficacy outcomes compared with more classical combinations or standard chemotherapy alone.
WORLD JOURNAL OF CLINICAL ONCOLOGY
(2021)
Article
Dohun Kim et al.
Journal of Chest Surgery
(2021)
Article
Oncology
Erik Jakobsen et al.
Summary: This study examined the clinical characteristics, incidence, mortality, and prevalence of lung cancer in Denmark from 2006 to 2015, and projected the future epidemiological profile through 2030. The findings suggest a shift towards earlier diagnosis and lower stages of lung cancer, as well as an increase in incidence and a decrease in mortality rates. It is projected that the number of prevalent lung cancer cases in Denmark will likely continue to increase significantly by the end of 2030.
Review
Medicine, General & Internal
Renqing Kuang et al.
Summary: This study aims to evaluate the effectiveness and safety of acupuncture combined with analgesics in alleviating cancer pain in patients with lung cancer. By conducting a systematic analysis of clinical trial data worldwide, it aims to provide reference basis for clinical treatment.
Article
Medicine, General & Internal
Li Zhao et al.
Summary: The study showed that comprehensive and systematic psychological nursing intervention significantly improved the mental health status of young patients with lung cancer surgery during the perioperative period.
Article
Environmental Sciences
Andrea Ricotti et al.
Summary: Treatment of lung cancer is based on the tumor stage and histological type, with histological confirmation of non-small-cell lung cancer being crucial for targeted therapeutic approaches. A validated procedure was developed to estimate the incidence and prevalence of non-small-cell and small-cell lung cancer from healthcare administrative data, showing high sensitivity and specificity. This procedure can be used to design subpopulation-based studies on lung cancer and optimize resource allocation for new targeted therapies.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Oncology
James E. Han et al.
Summary: The timing of surgery following neoadjuvant chemoradiation has a significant impact on the overall survival of patients with locally advanced non-small-cell lung cancer. Surgery performed within 7 weeks after chemoradiation completion is associated with better survival outcomes, while delaying surgery beyond 7 weeks is correlated with poorer survival. Additionally, early surgery within 66 days post-chemoradiation is associated with improved survival outcomes. Higher neoadjuvant radiotherapy doses may facilitate surgery within the optimal 7-week interval and minimize risks of complications.
Article
Oncology
Hang Zhao et al.
Summary: Neoadjuvant PD-(L)1 inhibitors show promise for locally advanced NSCLC, but severe irAEs can pose serious risks. Close monitoring and timely intervention are crucial in managing these adverse events.
TRANSLATIONAL LUNG CANCER RESEARCH
(2021)
Article
Oncology
Rui-Chen Ma et al.
Summary: This study confirmed that short-term pre- and postsurgery multimodal exercise intervention can significantly improve dyspnea, exercise capacity, and inspiratory capacity in lung cancer patients. Patients in the combined intervention group showed greater improvements in outcomes compared to those in the breathing exercise group.
CLINICAL JOURNAL OF ONCOLOGY NURSING
(2021)
Article
Respiratory System
Brett C. Bade et al.
CLINICS IN CHEST MEDICINE
(2020)
Article
Health Care Sciences & Services
Jan Jokelainen et al.
SCANDINAVIAN JOURNAL OF PRIMARY HEALTH CARE
(2019)
Article
Oncology
Rebecca L. Siegel et al.
CA-A CANCER JOURNAL FOR CLINICIANS
(2019)
Article
Oncology
Henri B. Wolff et al.
JOURNAL OF THORACIC ONCOLOGY
(2018)
Article
Oncology
Freddie Bray et al.
CA-A CANCER JOURNAL FOR CLINICIANS
(2018)
Article
Respiratory System
Eugenio Paci et al.
Article
Oncology
Wanqing Chen et al.
CA-A CANCER JOURNAL FOR CLINICIANS
(2016)
