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Recent advances in nanozymes for combating bacterial infection

MATERIALS CHEMISTRY FRONTIERS (2022)

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Article Engineering, Biomedical

Quaternized carbon quantum dots with broad-spectrum antibacterial activity for the treatment of wounds infected with mixed bacteria

Chengfei Zhao et al.

Summary: Bacterial resistance to antibiotics has become a serious global public health threat, highlighting the urgent need for new antimicrobial agents. In this study, quaternized carbon quantum dots (qCQDs) with broad-spectrum antibacterial activity were successfully synthesized. The qCQDs exhibited satisfactory antibacterial activity against both Gram-positive and Gram-negative bacteria. In rat models of wound infections, qCQDs effectively restored the weight of rats, reduced the mortality rate associated with severe infection, and promoted wound recovery and healing. Biosafety tests confirmed the absence of obvious toxic and side effects during the testing phase. Proteomics analysis revealed that qCQDs primarily targeted ribosomal proteins in Staphylococcus aureus (Gram-positive bacteria) and down-regulated proteins associated with the citrate cycle in Escherichia coli (Gram-negative bacteria). Real-time quantitative PCR confirmed the consistency between the changes in genes corresponding to these proteins and the proteomic results after qCQDs treatment, suggesting a new antibacterial mechanism of qCQDs different from previously reported carbon quantum dots with antibacterial properties.

ACTA BIOMATERIALIA (2022)

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Article Chemistry, Multidisciplinary

Diketopyrrolopyrrole-derived organic small molecular dyes for tumor phototheranostics

Qianli Ma et al.

Summary: This review summarizes the recent progress of various DPP-based organic small molecules in the field of phototheranostics over the last five years. The molecular structure design and their phototheranostics performances are discussed in detail, providing valuable references for the further development of DPP-based phototheranostics.

CHINESE CHEMICAL LETTERS (2022)

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Article Chemistry, Physical

Biodegradable gelatin/silver nanoparticle composite cryogel with excellent antibacterial and antibiofilm activity and hemostasis for Pseudomonas aeruginosa-infected burn wound healing

Ying Huang et al.

Summary: GT/Ag cryogels with outstanding antibacterial properties and effective absorption of wound exudates are excellent candidates for promoting burn wound repair.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2022)

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Article Chemistry, Physical

Spherical mesoporous Fe-N-C single-atom nanozyme for photothermal and catalytic synergistic antibacterial therapy

Youyou Feng et al.

Summary: The combination of mesoporous Fe-N-C SAzyme with photothermal treatment enhances the catalytic performance, resulting in a more effective antibacterial treatment compared to using single antibacterial methods.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2022)

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Review Virology

Phage therapy for secondary bacterial infections with COVID-19

Nannan Wu et al.

Summary: With over 200 million people affected and 4.5 million dead, the COVID-19 pandemic has become one of the greatest disasters in human history. Secondary bacterial infections (SBIs) are known complications of viral respiratory infections, and antibiotic treatments often fail to cure the patients. Phages, as natural killers of bacteria, are considered promising alternatives to antibiotics for treating pulmonary bacterial infections. However, their use for treating SBIs during virus pandemics like COVID-19 is still not well understood.

CURRENT OPINION IN VIROLOGY (2022)

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Article Optics

Orthogonal Aza-BODIPY-BODIPY dyad as heavy-atom free photosensitizer for photo-initiated antibacterial therapy

Dongliang Yang et al.

Summary: A novel halogen-free photosensitizer, NDB, was synthesized in this study. The ROS generation capability of NDB under 730 nm laser illumination was found to be 3-fold higher than that of the commercial ICG, suggesting its potential application in photo-initiated antibacterial therapy.

JOURNAL OF INNOVATIVE OPTICAL HEALTH SCIENCES (2022)

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Editorial Material Multidisciplinary Sciences

Field enhanced photocatalytic disinfection

Baoying Dai et al.

SCIENCE BULLETIN (2022)

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Article Engineering, Biomedical

An injectable and biodegradable hydrogel incorporated with photoregulated NO generators to heal MRSA-infected wounds

Xinyi Lv et al.

Summary: An injectable, degradable, and photoactivated antibacterial hydrogel (MPDA-BNN6@Gel) was developed for the treatment of infected wounds. The hydrogel could generate local hyperthermia and release large quantities of NO gas to treat the infection under laser irradiation. It was found that the hydrogel eradicated bacteria by damaging the cell membrane, genetic metabolism, and material energy. Additionally, the hydrogel promoted wound healing in vivo in the absence of laser irradiation.

ACTA BIOMATERIALIA (2022)

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Article Chemistry, Physical

Boron doped graphdiyne: A metal-free peroxidase mimetic nanozyme for antibacterial application

Xuelong Bi et al.

Summary: The abuse of conventional antibiotics leads to bacterial resistance, while nanozymes and boron doped GDY nanosheets show great potential as next generation nanobactericides, effectively killing various bacteria with excellent biocompatibility.

NANO RESEARCH (2022)

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Article Materials Science, Multidisciplinary

Promoted intramolecular photoinduced-electron transfer for multi-mode imaging-guided cancer photothermal therapy

Xin-Yu Qu et al.

Summary: The development of pH-sensitive NIR dye BTN with robust photothermal conversion efficiency and lysosome-targeting capability, fabricated as NPs with amphiphilic polymers, demonstrates outstanding imaging-guided photothermal therapy for tumor ablation in tumor-bearing nude mice.

RARE METALS (2022)

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Article Pharmacology & Pharmacy

Photocatalytic Cu2WS4 Nanocrystals for Efficient Bacterial Killing and Biofilm Disruption

Heng Dong et al.

International Journal of Nanomedicine (2022)

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Article Biochemistry & Molecular Biology

POD Nanozyme optimized by charge separation engineering for light/pH activated bacteria catalytic/photodynamic therapy

Changyu Gao et al.

Summary: This article introduces a novel Ag/Bi2MoO6 (Ag/BMO) nanozyme optimized by charge separation engineering with photoactivated sustainable peroxidase-mimicking activities and NIR-II photodynamic performance, which exhibits satisfactory bactericidal performance against MRSA.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2022)

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Article Engineering, Environmental

Recoverable peroxidase-like Fe3O4@MoS2-Ag nanozyme with enhanced antibacterial ability

Feng Wei et al.

Summary: The study successfully demonstrated the efficient antibacterial performance of Fe3O4@MoS2-Ag nanozyme against E. coli, and revealed a synergistic disinfection effect. Through the collaborative work of peroxidase-like activity, photothermal effect, and Ag+ leakage, the nanozyme could accurately and rapidly attack bacterial membranes, showing broad-spectrum antibacterial capabilities.

CHEMICAL ENGINEERING JOURNAL (2021)

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Article Chemistry, Physical

Development of novel topical formulation from fullerene with antibacterial activity againstPropionibacterium acnes

Yasaman Ghabdian et al.

Summary: The study developed a water soluble fullerene derivative, Chi-Gly-Ful NPs, for acne treatment with antibacterial activity. Chi-Gly-Ful NPs showed inhibitory effects on Propionibacterium acnes in vitro and exhibited no cytotoxicity to cells.

FULLERENES NANOTUBES AND CARBON NANOSTRUCTURES (2021)

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Review Chemistry, Physical

Carbon-based nanozymes for biomedical applications

Hui Ding et al.

Summary: Nanozymes are nanomaterials with enzyme-like properties that address the limitations of traditional enzymes and offer multifunctional platforms for biomedical applications. Carbon nanomaterials, with well-defined structures, have shown to be ideal substitutes for traditional enzymes in mimicking the catalytic centers of natural enzymes.

NANO RESEARCH (2021)

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Article Engineering, Environmental

Photodynamic and photothermal co-driven CO-enhanced multi-mode synergistic antibacterial nanoplatform to effectively fight against biofilm infections

Xiaojun Cai et al.

Summary: A CO-enhanced multi-mode synergistic antibacterial nanoplatform (ICG&CO@G3KBPY) has been successfully developed to combat biofilm infections, with enhanced biofilm penetration, antibacterial activity, and anti-inflammatory effects. The platform rapidly generates CO under the co-driven effects of PTT and PDT, significantly improving the efficacy of biofilm eradication while alleviating inflammation caused by bacterial infection, PTT, and PDT. This study provides an efficient and safe multi-mode synergistic antibacterial strategy for treating biofilm infections.

CHEMICAL ENGINEERING JOURNAL (2021)

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Article Biochemistry & Molecular Biology

Multifunctional chitosan-copper-gallic acid based antibacterial nanocomposite wound dressing

Xinyu Sun et al.

Summary: In this study, chitosan-copper-gallic acid nanocomposites with dual-functional nanoenzyme characteristics were successfully prepared, showing oxidase-like and peroxidase-like activities that promote the generation of hydrogen peroxide and hydroxyl radicals, leading to excellent antibacterial properties.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

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Review Biochemistry & Molecular Biology

State of the Art in the Antibacterial and Antiviral Applications of Carbon-Based Polymeric Nanocomposites

Ana M. Diez-Pascual

Summary: Carbon nanomaterials, with their exceptional properties, have great potential for antibacterial applications, but challenges such as poor dispersibility and cost need to be addressed before full exploration. Integrating carbon nanomaterials within antimicrobial polymeric matrices is one way to overcome these challenges. Research in this area is ongoing and has the potential to expand into various application fields.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

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Review Biochemistry & Molecular Biology

Recent advances in Cu(II)/Cu(I)-MOFs based nano-platforms for developing new nano-medicines

Yingman Sun et al.

Summary: Metal organic frameworks (MOFs) are versatile materials with interesting chemical and structural properties, finding applications in various fields such as catalysis, sensing and drug delivery. Among them, copper-based MOF nanomaterials have unique biological activity and potential in medicine, especially in the treatment of cancer and other diseases.

JOURNAL OF INORGANIC BIOCHEMISTRY (2021)

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Article Nanoscience & Nanotechnology

Copper Sulfide Nanoassemblies for Catalytic and Photoresponsive Eradication of Bacteria from Infected Wounds

Amit Nain et al.

Summary: BSA-encapsulated copper sulfide nanocrystals (CuS NCs) were prepared and exhibited enzyme-like and photodynamic activities. under NIR laser irradiation, the antimicrobial response was significantly enhanced and >99% of bacteria were eradicated in just 1 min. The BSA-CuS NCs showed insignificant cytotoxicity and hemolysis, making them highly biocompatible bactericides for effective bacteria eradication in preclinical applications.

ACS APPLIED MATERIALS & INTERFACES (2021)

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Article Environmental Sciences

Synthesis and characterization of cotton-silver-graphene quantum dots (cotton/Ag/GQDs) nanocomposite as a new antibacterial nanopad

Hakimeh Teymourinia et al.

Summary: This study fabricated antibacterial pads using graphene quantum dots, with the cotton/GQDs/Ag pad showing the highest antibacterial activity and significantly improving the efficacy of Ag nanoparticles against Staphylococcus aureus and Escherichia coli.

CHEMOSPHERE (2021)

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Article Pharmacology & Pharmacy

Silver nanoparticles obtained from Brazilian pepper extracts with synergistic anti-microbial effect: production, characterization, hydrogel formulation, cell viability, and in vitro efficacy

Daniele M. de Oliveira et al.

Summary: The synthesis of silver nanoparticles using plant extracts is a green approach which involves bioreduction mediated by plant enzymes and proteins. The produced nanoparticles showed no cytotoxicity and demonstrated enhanced microbial inhibition, suggesting their potential as an alternative to combat bacterial resistance.

PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY (2021)

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Article Nanoscience & Nanotechnology

Au-Au/IrO2@Cu(PABA) Reactor with Tandem Enzyme-Mimicking Catalytic Activity for Organic Dye Degradation and Antibacterial Application

Yingying Zhong et al.

Summary: The innovative synthesis of Au-Au/IrO2 nanocomposite with tandem enzyme-mimicking activity leads to the preparation of a highly stable and reusable Au-Au/IrO2@Cu(PABA) reactor. This reactor exhibits excellent catalytic efficiency, organic solvent stability, acid resistance, and antibacterial activity, making it suitable for organic dye degradation and antibacterial applications.

ACS APPLIED MATERIALS & INTERFACES (2021)

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Article Metallurgy & Metallurgical Engineering

More severe toxicity of gold nanoparticles with rougher surface in mouse hippocampal neurons

Lin Xin et al.

Summary: The study showed that the shape of gold nanoparticles (GNPs) affects the voltage-dependent sodium channel and action potential of hippocampal CA1 neurons in mice. GNPs inhibited the sodium current amplitudes and shifted the voltage-dependence curve, leading to increased neuronal excitability and altered action potential properties. Nanoflower-shaped GNPs had the most significant effects on action potential properties, indicating that the neurotoxicity of GNPs is dependent on surface roughness.

JOURNAL OF CENTRAL SOUTH UNIVERSITY (2021)

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Review Biotechnology & Applied Microbiology

Tetrahedral DNA nanostructures for effective treatment of cancer: advances and prospects

Jianqin Yan et al.

Summary: DNA nanostructures, particularly tetrahedral DNA nanostructures (TDN), have shown great potential in biomedical applications such as drug delivery. TDN, known for their stability and biocompatibility, can be easily synthesized and modified for use as carriers for various drugs and imaging probes. This review summarizes the functional modification methods and applications of TDN in cancer treatment, and also discusses future challenges to increase their applicability.

JOURNAL OF NANOBIOTECHNOLOGY (2021)

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Article Engineering, Environmental

Visible light-induced antibacterial effect of MoS2: Effect of the synthesis methods

Manman Zhang et al.

Summary: Molybdenum disulfides (MoS2) prepared through different methods exhibited varying levels of photo-induced antibacterial properties, with intercalation method showing the highest antibacterial effect due to its higher metal phase content, better light responsiveness, and smaller size. The main active substance in the photo-induced antibacterial process was found to be electrons, as determined through capture agent experiment and ESR test.

CHEMICAL ENGINEERING JOURNAL (2021)

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Article Engineering, Biomedical

Copper single-atom catalysts with photothermal performance and enhanced nanozyme activity for bacteria-infected wound therapy

Xianwen Wang et al.

Summary: This study highlights the enhanced catalytic activity of nanozymes through the construction of Cu SASs/NPC for photothermal-catalytic antibacterial treatment strategy. The introduction of Cu significantly improves the catalytic performance of nanozymes, effectively killing bacteria and improving sterilization effect. The synergistic PTT-catalytic antibacterial strategy shows almost 100% antibacterial efficiency against E. coli and MRSA, demonstrating wide bio-applications of Cu-containing catalysts in antibacterial and anti-infective treatments.

BIOACTIVE MATERIALS (2021)

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Article Engineering, Biomedical

Infection microenvironment-activated nanoparticles for NIR-II photoacoustic imaging-guided photothermal/chemodynamic synergistic anti-infective therapy

Nan Yang et al.

Summary: A novel theranostic platform based on Cu2O nanoparticles was successfully constructed, which can precisely identify and eliminate bacteria in the infection microenvironment, showing a good antibacterial effect against drug-resistant bacteria.

BIOMATERIALS (2021)

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Article Biophysics

DNA-encoded bimetallic Au-Pt dumbbell nanozyme for high-performance detection and eradication of Escherichia coli O157:H7

Chang Lu et al.

Summary: This study successfully synthesized anisotropic dumbbell-like Au-Pt nanoparticles with excellent catalytic and anti-bacterial activities through a DNA-programming strategy, which were applied in the detection and eradication of pathogenic bacteria. The research also discovered the DNA sequence-dependent growth of bimetallic nanoparticles and highlighted the high nanozyme catalytic activity and photothermal conversion efficiency of the Au-Pt nanoparticles.

BIOSENSORS & BIOELECTRONICS (2021)

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Article Engineering, Environmental

An overview of the use of nanozymes in antibacterial applications

Linqiang Mei et al.

Summary: The emergence of nanozymes as promising candidates for combating bacteria is driven by their combination of advantages from nanomaterials and natural enzymes, resulting in low cost, good stability, controllable size, easy preparation, multifunctionality, and superior catalytic activity, making them potent antibacterial agents with broad-spectrum antibacterial abilities and biocompatibility.

CHEMICAL ENGINEERING JOURNAL (2021)

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Article Environmental Sciences

A novel biogenic Allium cepa leaf mediated silver nanoparticles for antimicrobial, antioxidant, and anticancer effects on MCF-7 cell line

M. Mani et al.

Summary: In this study, Allium cepa leaf extract was used to biosynthesize silver nanoparticles with excellent stability and antioxidant, anticancer, and antimicrobial activities. The synthesized nanoparticles were extensively characterized and confirmed to have a spherical structure with a size of 13 nm and a silver content of 30.33%. Additionally, the nanoparticles showed better cytotoxic activity against breast cancer cells and exhibited antimicrobial effectiveness against gram-positive and gram-negative bacteria.

ENVIRONMENTAL RESEARCH (2021)

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Article Nanoscience & Nanotechnology

Near-Infrared Light Enhanced Peroxidase-Like Activity of PEGylated Palladium Nanozyme for Highly Efficient Biofilm Eradication

Sijin Xiang et al.

Summary: Eradication of biofilm-growing bacteria is crucial for infection control. A PEGylated palladium nanozyme with peroxidase-like activity shows high efficiency in destroying biofilm matrix and killing bacteria. The synergistic treatment based on Pd-PEG+H2O2+NIR combination exhibits outstanding antibacterial effects with low biotoxicity.

JOURNAL OF BIOMEDICAL NANOTECHNOLOGY (2021)

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Review Chemistry, Physical

Facile synthesis and applications of carbon nanotubes in heavy-metal remediation and biomedical fields: A comprehensive review

Robert Birundu Onyancha et al.

Summary: Carbon nanotubes (CNTs) have unique properties that make them applicable in various fields, particularly in medicine and environmental applications. Through chemical modification and functionalization, the parameters of CNTs can be controlled to improve functionality. CNTs have the potential to revolutionize human life by offering improved healthcare services and ensuring a safer environment.

JOURNAL OF MOLECULAR STRUCTURE (2021)

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Article Chemistry, Multidisciplinary

L-Arg-Rich Amphiphilic Dendritic Peptide as a Versatile NO Donor for NO/Photodynamic Synergistic Treatment of Bacterial Infections and Promoting Wound Healing

Jingwu Zhu et al.

Summary: This study presents a novel synergistic antibacterial strategy based on PDT and NO gas therapy using Ce6@Arg-ADP as a carrier, which shows enhanced biofilm penetration and antibacterial effects. The combination of O-1(2) and NO offers notable synergistic effects, promoting wound healing effectively.

SMALL (2021)

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Review Biotechnology & Applied Microbiology

Chemodynamic nanomaterials for cancer theranostics

Jingqi Xin et al.

Summary: This article discusses the potential of chemodynamic therapy (CDT) based on Fenton and Fenton-like reactions in enhancing anticancer efficacy, including direct killing of cancer cells, indirectly enhancing therapeutic efficacy, and diagnosing and monitoring cancer therapy.

JOURNAL OF NANOBIOTECHNOLOGY (2021)

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Review Nanoscience & Nanotechnology

Recent development of nanomedicine for the treatment of bacterial biofilm infections

Weijun Xiu et al.

Summary: This review focuses on the recent advances in nanotechnology-based strategies and nanoagents for combating bacterial biofilm infections. It discusses typical antibiofilm nanotechnologies, smart nanoagents responsive to biofilm microenvironment, and promising antibiofilm approaches, such as theranostics, biofilm structure destruction, and quorum sensing inhibition. The current challenges and future directions in antibiofilm nanotechnologies are also discussed.

VIEW (2021)

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Article Chemistry, Multidisciplinary

Promising antimicrobial and antibiofilm activities of reduced graphene oxide-metal oxide (RGO-NiO, RGO-AgO, and RGO-ZnO) nanocomposites

Sherif Elbasuney et al.

Summary: The synthesized nanocomposites exhibited outstanding antimicrobial activity against various bacteria and fungi, along with antibiofilm activity. Under UV illumination, these composites showed significant inhibition effects on pathogenic microorganisms, representing a promising strategy for managing infectious diseases.

RSC ADVANCES (2021)

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Article Chemistry, Multidisciplinary

Nanozymes Inspired by Natural Enzymes

Ruofei Zhang et al.

Summary: Nanozymes, nanomaterials with enzyme-like activities, have attracted significant attention in recent years as potential substitutes and competitors for natural enzymes. The key focus in this field is on creating nanozymes with catalytic performance comparable to or surpassing that of natural enzymes. By employing a bioinspired strategy, researchers have successfully synthesized high-activity nanozymes that show similar catalytic activities to natural enzymes, establishing a new hot topic in nanozyme research.

ACCOUNTS OF MATERIALS RESEARCH (2021)

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Manganese dioxide nanozyme for reactive oxygen therapy of bacterial infection and wound healing

Li Liu et al.

Summary: The research team has developed a nanozyme that generates reactive oxygen species with high stability and biocompatibility, effectively killing multidrug resistant pathogens, preventing and disrupting biofilm formation, and demonstrating excellent antibacterial performance. This oxidative therapy based nanozyme shows promising potential in treating skin and soft tissue infections in mice.

BIOMATERIALS SCIENCE (2021)

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Fluorescence resonance energy transfer enhanced photothermal and photodynamic antibacterial therapy post a single injection

Lei Xue et al.

Summary: This study successfully prepared near-infrared light-triggered theranostic nanoparticles that could targeted assembly and effectively destroy multidrug-resistant bacteria through synergistic photothermal and photodynamic therapy.

MATERIALS CHEMISTRY FRONTIERS (2021)

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Jingjing Huo et al.

Summary: Given the challenges of bacterial resistance and biofilm protection, photothermal therapy (PTT)-derived multimodal synergistic treatments have emerged as a promising approach to combat bacterial infections. By combining PTT with chemotherapy, photo-dynamic/catalytic therapy, immunotherapy, and sonodynamic therapy, enhanced bactericidal activity can be achieved while minimizing potential side effects.

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Exfoliated FePS3 nanosheets for T1-weighted magnetic resonance imaging-guided near-infrared photothermal therapy in vivo

Ying Zhang et al.

Summary: The study successfully synthesized FePS3-PEG nanosheets with excellent photothermal conversion efficiency and magnetic resonance imaging effects, making them promising for T-1 weighted MRI-guided near-infrared photothermal therapy for cancer treatment.

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A photo-triggered antifungal nanoplatform with efflux pump and heat shock protein reversal activity for enhanced chemo-photothermal synergistic therapy

Dongliang Yang et al.

Summary: The newly developed photo-triggered multifunctional nanoplatform can effectively eliminate drug-resistant fungi by releasing a quorum sensing molecule and an antifungal drug, and destroying the integrity of fungal cell membrane, inhibiting the expression of drug efflux pumps and heat shock proteins, and effectively blocking the hyphal and biofilm formation of fungi.

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Nanoscale metal-organic frameworks for tumor phototherapy

Xuan Huang et al.

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Conductive all-carbon nanotube layers: Results on attractive physicochemical, anti-bacterial, anticancer and biocompatibility properties

Aleksandra Benko et al.

Summary: The study focused on the physicochemical, electrochemical, and biological performance of four types of all-carbon nanotube layers, finding that these materials have inhibitory effects on the proliferation of bacteria and cancer cells, while having no negative effects on mammalian cells and not requiring drug intervention.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021)

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Gold nanoplates with superb photothermal efficiency and peroxidase-like activity for rapid and synergistic antibacterial therapy

Lu Yan et al.

Summary: Gold nanoplates show high photothermal conversion efficiency and peroxidase-like activity, and when combined with low H2O2 concentration, low AuNPT dosage, and laser irradiation, they exhibit excellent synergistic antibacterial ability and wound healing in vivo.

CHEMICAL COMMUNICATIONS (2021)

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Bienzymatic synergism of vanadium oxide nanodots to efficiently eradicate drug-resistant bacteria during wound healing in vivo

Weishuai Ma et al.

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Green synthesis of bimetallic copper-silver nanoparticles and their application in catalytic and antibacterial activities

Jawhara Al-Haddad et al.

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Surface Charge Switchable Supramolecular Nanocarriers for Nitric Oxide Synergistic Photodynamic Eradication of Biofilms

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Bacteria Capture and Inactivation with Functionalized Multi-Walled Carbon Nanotubes (MWCNTs)

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Ultra-efficient Antibacterial System Based on Photodynamic Therapy and CO Gas Therapy for Synergistic Antibacterial and Ablation Biofilms

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Bimetallic CuCo2S4 Nanozymes with Enhanced Peroxidase Activity at Neutral pH for Combating Burn Infections

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Fe3O4 Nanoparticles Attenuated Salmonella Infection in Chicken Liver Through Reactive Oxygen and Autophagy via PI3K/Akt/mTOR Signaling

Yiru Shen et al.

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Supramolecular Modulation of Antibacterial Activity of Ambroxol by Cucurbit[7]uril

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Bimetallic Nanoparticles for Antimicrobial Applications

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Bimetallic Ag/Cu incorporated into chemically exfoliated MoS2 nanosheets to enhance its antibacterial potential: in silico molecular docking studies

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Construction of Self-activated Cascade Metal-Organic Framework/Enzyme Hybrid Nanoreactors as Antibacterial Agents

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Injectable self-healing supramolecular hydrogels with conductivity and photo-thermal antibacterial activity to enhance complete skin regeneration

Beilin Zhang et al.

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