4.7 Review

Recent advances in nanozymes for combating bacterial infection

期刊

MATERIALS CHEMISTRY FRONTIERS
卷 6, 期 18, 页码 2596-2609

出版社

ROYAL SOC CHEMISTRY
DOI: 10.1039/d2qm00511e

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资金

  1. NNSF of China [52103166]
  2. NSF of Jiangsu Province [BK20200710]
  3. Jiangsu Postdoctoral Science Foundation [51204087]
  4. Development of Science and Technology of Nanjing [YKK19094]

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Bacterial infection poses a significant threat to global public health. The overuse and misuse of antibiotics have led to the emergence of antibiotic-resistant strains, exacerbated by the COVID-19 pandemic. Thus, there is an urgent need for alternative antibacterial treatments. Nanozymes, with their broad-spectrum antibacterial activity, low drug resistance, and high stability, have emerged as promising new antibacterial agents.
Bacterial infection is a major threat to public health around the world. Currently, antibiotics remain the most extensive mode of medical treatment for bacterial infection. However, the overuse and misuse of antibiotics have exacerbated the emergence of antibiotic-resistant strains, especially during the COVID-19 pandemic. In addition, the improper and excessive use of biocides and disinfectants has a catastrophic impact on antibiotic management plans worldwide. Therefore, there is an urgent need for alternative antibacterial treatments to alleviate this crisis. In recent years, nanozymes have become promising new antibacterial agents because of their broad-spectrum antibacterial activity, less drug resistance, and high stability. This review focuses on the classification of nanozymes and research progress of nanozymes as antibacterial agents, as well as perspectives for future research in this field.

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