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Fernando G. Herrera et al.
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Jiacheng Bi et al.
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Frank Cichocki et al.
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NATURE COMMUNICATIONS (2019)
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T. A. Chan et al.
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CANCER IMMUNOLOGY RESEARCH (2019)
T Regulatory Cells and Priming the Suppressive Tumor Microenvironment
Christina M. Paluskievicz et al.
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Tumor Associated Neutrophils. Their Role in Tumorigenesis, Metastasis, Prognosis and Therapy
Maria Teresa Masucci et al.
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Comparison of the effects of photon, proton and carbon-ion radiation on the ecto-calreticulin exposure in various tumor cell lines
Yangle Huang et al.
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The Reciprocity between Radiotherapy and Cancer Immunotherapy
Yifan Wang et al.
CLINICAL CANCER RESEARCH (2019)
The immunological consequences of radiation-induced DNA damage
Anna C. Wilkins et al.
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Eric D. Brooks et al.
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MDSC; the Most Important Cell You Have Never Heard Of
R. J. Tesi
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Local Irradiation Sensitized Tumors to Adoptive T Cell Therapy via Enhancing the Cross-Priming, Homing, and Cytotoxicity of Antigen-Specific CD8 T Cells
Jin-Zhi Lai et al.
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Omer M. Ozpiskin et al.
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Hari Menon et al.
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Overcoming Resistance to Combination Radiation-Immunotherapy: A Focus on Contributing Pathways Within the Tumor Microenvironment
Laurel B. Darragh et al.
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M. E. Rodriguez-Ruiz et al.
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Hong Yeol Yoon et al.
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Implications of macrophage polarization in autoimmunity
Samanta C. Funes et al.
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Maureen L. Aliru et al.
IMMUNOTHERAPY (2018)
Safety and Clinical Activity of Pembrolizumab and Multisite Stereotactic Body Radiotherapy in Patients With Advanced Solid Tumors
Jason J. Luke et al.
JOURNAL OF CLINICAL ONCOLOGY (2018)
Low-Dose Radiation Promotes Dendritic Cell Migration and IL-12 Production via the ATM/NF-KappaB Pathway
Nan Yu et al.
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Immunological Mechanisms Responsible for Radiation-Induced Abscopal Effect
Maria E. Rodriguez-Ruiz et al.
TRENDS IN IMMUNOLOGY (2018)
Cancer Radiosensitizers
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Caspase-1 from Human Myeloid-Derived Suppressor Cells Can Promote T Cell-Independent Tumor Proliferation
Qi Zeng et al.
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Exosomes Shuttle TREX1-Sensitive IFN-Stimulatory dsDNA from Irradiated Cancer Cells to DCs
Julie M. Diamond et al.
CANCER IMMUNOLOGY RESEARCH (2018)
Radiation-Induced Chromosomal Aberrations and Immunotherapy: Micronuclei, Cytosolic DNA, and Interferon-Production Pathway
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Yang Liu et al.
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Low dose radiation primed iNOS+M1macrophages modulate angiogenic programming of tumor derived endothelium
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Nuclear envelope assembly defects link mitotic errors to chromothripsis
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S. J. Antonia et al.
NEW ENGLAND JOURNAL OF MEDICINE (2018)
In Situ Vaccination with a TLR9 Agonist and Local Low-Dose Radiation Induces Systemic Responses in Untreated Indolent Lymphoma
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Assaf Marcus et al.
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H. Barsoumian et al.
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Radiotherapy induces responses of lung cancer to CTLA-4 blockade
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NATURE MEDICINE (2018)
Radiation-Induced Liver Disease and Modern Radiotherapy
Eugene J. Koay et al.
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Tumour-vasculature development via endothelial-to-mesenchymal transition after radiotherapy controls CD44v6(+) cancer cell and macrophage polarization
Seo-Hyun Choi et al.
NATURE COMMUNICATIONS (2018)
Previous Radiotherapy Increases the Efficacy of IL-2 in Malignant Pleural Effusion: Potential Evidence of a Radio-Memory Effect?
Dawei Chen et al.
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Zachary S. Buchwald et al.
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Wilfred Ngwa et al.
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Andrew J. Gunderson et al.
ADVANCES IN RADIATION ONCOLOGY (2018)
NKG2D-Based CAR T Cells and Radiotherapy Exert Synergistic Efficacy in Glioblastoma
Tobias Weiss et al.
CANCER RESEARCH (2018)
Decreased Suppression and Increased Phosphorylated STAT3 in Regulatory T Cells are Associated with Benefit from Adjuvant PD-1 Blockade in Resected Metastatic Melanoma
David M. Woods et al.
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Dermatologic Reactions to Immune Checkpoint Inhibitors Skin Toxicities and Immunotherapy
Vincent Sibaud
AMERICAN JOURNAL OF CLINICAL DERMATOLOGY (2018)
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CA-A CANCER JOURNAL FOR CLINICIANS (2017)
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R. Nedaeinia et al.
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Regulatory T cells in cancer immunotherapy
Atsushi Tanaka et al.
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Ipilimumab with Stereotactic Ablative Radiation Therapy: Phase I Results and Immunologic Correlates from Peripheral T Cells
Chad Tang et al.
CLINICAL CANCER RESEARCH (2017)
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Qiaohong Wang et al.
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Hu Liu et al.
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Combined Immune Checkpoint Blockade and Radiation Therapy: Timing and Dose Fractionation Associated with Greatest Survival Duration Among Over 750 Treated Patients
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Andrew Bang et al.
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cGAS surveillance of micronuclei links genome instability to innate immunity
Karen J. Mackenzie et al.
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Ralph R. Weichselbaum et al.
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Durvalumab after Chemoradiotherapy in Stage III Non-Small-Cell Lung Cancer
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Yiftah Barsheshet et al.
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Dung T. Le et al.
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Yuki Muroyama et al.
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Dmitry I. Gabrilovich
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Exosomes as diagnostic and predictive biomarkers in lung cancer
Pablo Reclusa et al.
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ACS NANO (2017)
Fractionated Radiation Therapy Stimulates Antitumor Immunity Mediated by Both Resident and Infiltrating Polyclonal T-cell Populations when Combined with PD-1 Blockade
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Shape-Dependent Radiosensitization Effect of Gold Nanostructures in Cancer Radiotherapy: Comparison of Gold Nanoparticles, Nanospikes, and Nanorods
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ACS APPLIED MATERIALS & INTERFACES (2017)
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Jan T. Poleszczuk et al.
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ANNUAL REVIEW OF IMMUNOLOGY VOL 33 (2015)
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CANCER LETTERS (2015)
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Claire Vanpouille-Box et al.
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Type I interferons in anticancer immunity
Laurence Zitvogel et al.
NATURE REVIEWS IMMUNOLOGY (2015)
The tumour microenvironment after radiotherapy: mechanisms of resistance and recurrence
Holly E. Barker et al.
NATURE REVIEWS CANCER (2015)
Abscopal effect of low-LET γ-radiation mediated through Rel protein signal transduction in a mouse model of nontargeted radiation response
S. Aravindan et al.
CANCER GENE THERAPY (2014)
SIRT1 Limits the Function and Fate of Myeloid-Derived Suppressor Cells in Tumors by Orchestrating HIF-1α-Dependent Glycolysis
Guangwei Liu et al.
CANCER RESEARCH (2014)
Prognostic and Predictive Values of the Immunoscore in Patients with Rectal Cancer
Maria-Gabriela Anitei et al.
CLINICAL CANCER RESEARCH (2014)
An Individual Patient Data Metaanalysis of Outcomes and Prognostic Factors After Treatment of Oligometastatic Non-Small-Cell Lung Cancer
Allison B. Ashworth et al.
CLINICAL LUNG CANCER (2014)
STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors
Liufu Deng et al.
IMMUNITY (2014)
Treg functional stability and its responsiveness to the microenvironment
Joseph Barbi et al.
IMMUNOLOGICAL REVIEWS (2014)
Low-dose splenic radiation inhibits liver tumor development of rats through functional changes in CD4+CD25+Treg cells
Baofeng Wang et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2014)
The Effect of Radiation on the Immune Response to Cancers
Bonggoo Park et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2014)
Irradiation and anti-PD-L1 treatment synergistically promote antitumor immunity in mice
Liufu Deng et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
Cytosolic-DNA-Mediated, STING-Dependent Proinflammatory Gene Induction Necessitates Canonical NF-κB Activation through TBK1
Takayuki Abe et al.
JOURNAL OF VIROLOGY (2014)
Cancer Epigenetics: Tumor Heterogeneity, Plasticity of Stem-like States, and Drug Resistance
Hariharan Easwaran et al.
MOLECULAR CELL (2014)
Ipilimumab versus placebo after radiotherapy in patients with metastatic castration-resistant prostate cancer that had progressed after docetaxel chemotherapy (CA184-043): a multicentre, randomised, double-blind, phase 3 trial
Eugene D. Kwon et al.
LANCET ONCOLOGY (2014)
Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients
Roy S. Herbst et al.
NATURE (2014)
Double-strand break repair: 53BP1 comes into focus
Stephanie Panier et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)
Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma
Alexandra Snyder et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Contextual regulation of pancreatic cancer stem cell phenotype and radioresistance by pancreatic stellate cells
Osama Al-Assar et al.
RADIOTHERAPY AND ONCOLOGY (2014)
The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop
Xu Zhang et al.
CELL REPORTS (2014)
Effects of Single or Combined Treatments with Radiation and Chemotherapy on Survival and Danger Signals Expression in Glioblastoma Cell Lines
Francesca Pasi et al.
BIOMED RESEARCH INTERNATIONAL (2014)
Molecular mechanisms that influence the macrophage M1-M2 polarization balance
Nan Wang et al.
FRONTIERS IN IMMUNOLOGY (2014)
Abscopal effects of radiotherapy on advanced melanoma patients who progressed after ipilimumab immunotherapy
Antonio M. Grimaldi et al.
ONCOIMMUNOLOGY (2014)
Radiation fosters dose-dependent and chemotherapy-induced immunogenic cell death
Encouse B. Golden et al.
ONCOIMMUNOLOGY (2014)
Concerted action of Nrf2-ARE pathway, MRN complex, HMGB1 and inflammatory cytokines - Implication in modification of radiation damage
Anuranjani et al.
REDOX BIOLOGY (2014)
Revisiting STAT3 signalling in cancer: new and unexpected biological functions
Hua Yu et al.
NATURE REVIEWS CANCER (2014)
Akt Promotes Irradiation-Induced Regulatory T-Cell Survival in Hepatocellular Carcinoma
Chuan-Gang Li et al.
AMERICAN JOURNAL OF THE MEDICAL SCIENCES (2013)
Monocytic Myeloid-Derived Suppressor Cells Accumulate in Renal Transplant Patients and Mediate CD4+Foxp3+ Treg Expansion
Y. Luan et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2013)
The Multifaceted Functions of Neutrophils
Tanya N. Mayadas et al.
Annual Review of Pathology-Mechanisms of Disease (2013)
Low-Dose Irradiation Programs Macrophage Differentiation to an iNOS+/M1 Phenotype that Orchestrates Effective T Cell Immunotherapy
Felix Klug et al.
CANCER CELL (2013)
TLR9 Signaling in the Tumor Microenvironment Initiates Cancer Recurrence after Radiotherapy
Chan Gao et al.
CANCER RESEARCH (2013)
CSF1R Signaling Blockade Stanches Tumor-Infiltrating Myeloid Cells and Improves the Efficacy of Radiotherapy in Prostate Cancer
Jingying Xu et al.
CANCER RESEARCH (2013)
The Impact of the Myeloid Response to Radiation Therapy
Michael J. Gough et al.
CLINICAL & DEVELOPMENTAL IMMUNOLOGY (2013)
Polyunsaturated fatty acids promote the expansion of myeloid-derived suppressor cells by activating the JAK/STAT3 pathway
Dehong Yan et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2013)
Oncology Meets Immunology: The Cancer-Immunity Cycle
Daniel S. Chen et al.
IMMUNITY (2013)
Combining Radiotherapy and Cancer Immunotherapy: A Paradigm Shift
Silvia C. Formenti et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2013)
TGF-β-induced miR10a/b expression promotes human glioma cell migration by targeting PTEN
Shihai Liu et al.
MOLECULAR MEDICINE REPORTS (2013)
Radical treatment of synchronous oligometastatic non-small cell lung carcinoma (NSCLC): Patient outcomes and prognostic factors
Gwendolyn H. M. J. Griffioen et al.
LUNG CANCER (2013)
Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP
Andrea Ablasser et al.
NATURE (2013)
Changes in the Secretory Profile of NSCLC-Associated Fibroblasts after Ablative Radiotherapy: Potential Impact on Angiogenesis and Tumor Growth
Turid Hellevik et al.
TRANSLATIONAL ONCOLOGY (2013)
miR-182 and miR-10a Are Key Regulators of Treg Specialisation and Stability during Schistosome and Leishmania-associated Inflammation
Samir Kelada et al.
PLOS PATHOGENS (2013)
The irradiated tumor microenvironment: role of tumor-associated macrophages in vascular recovery
Jeffery S. Russell et al.
FRONTIERS IN PHYSIOLOGY (2013)
Neutrophil recruitment and function in health and inflammation
Elzbieta Kolaczkowska et al.
NATURE REVIEWS IMMUNOLOGY (2013)
Neutrophil Function: From Mechanisms to Disease
Borko Amulic et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 30 (2012)
New Challenges in Endpoints for Drug Development in Advanced Melanoma
Antoni Ribas et al.
CLINICAL CANCER RESEARCH (2012)
Maximizing Tumor Immunity With Fractionated Radiation
Doerthe Schaue et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2012)
Smad3 binding to the foxp3 enhancer is dispensable for the development of regulatory T cells with the exception of the gut
Susan M. Schlenner et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2012)
Radiotherapy Promotes Tumor-Specific Effector CD8+ T Cells via Dendritic Cell Activation
Anurag Gupta et al.
JOURNAL OF IMMUNOLOGY (2012)
Immunologic Correlates of the Abscopal Effect in a Patient with Melanoma
Michael A. Postow et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Chemotherapeutics and Radiation Stimulate MHC Class I Expression through Elevated Interferon-beta Signaling in Breast Cancer Cells
Shan Wan et al.
PLOS ONE (2012)
Expression of NF-κB p50 in Tumor Stroma Limits the Control of Tumors by Radiation Therapy
Marka R. Crittenden et al.
PLOS ONE (2012)
Cancer-associated fibroblasts from human NSCLC survive ablative doses of radiation but their invasive capacity is reduced
Turid Hellevik et al.
RADIATION ONCOLOGY (2012)
Protein Kinase B Promotes Radiation-Induced Regulatory T Cell Survival in Bladder Carcinoma
M. Wang et al.
SCANDINAVIAN JOURNAL OF IMMUNOLOGY (2012)
In the field: exploiting the untapped potential of immunogenic modulation by radiation in combination with immunotherapy for the treatment of cancer
Anna R. Kwilas
Frontiers in Oncology (2012)
The confluence of radiotherapy and immunotherapy
Byron Bumette et al.
FRONTIERS IN ONCOLOGY (2012)
Irradiation promotes an M2 macrophage phenotype in tumor hypoxia
Chi-Shiun Chiang et al.
FRONTIERS IN ONCOLOGY (2012)
Neutrophils in the activation and regulation of innate and adaptive immunity
Alberto Mantovani et al.
NATURE REVIEWS IMMUNOLOGY (2011)
Blockade of Tumor Necrosis Factor α Signaling in Tumor-Associated Macrophages as a Radiosensitizing Strategy
Yuru Meng et al.
CANCER RESEARCH (2010)
Recruitment of Myeloid but not Endothelial Precursor Cells Facilitates Tumor Regrowth after Local Irradiation
Sergey V. Kozin et al.
CANCER RESEARCH (2010)
2-Gy whole-body irradiation significantly alters the balance of CD4+CD25- T effector cells and CD4+CD25+Foxp3+ T regulatory cells in mice
Yanyan Qu et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2010)
Hierarchy of immunosuppressive strength among myeloid-derived suppressor cell subsets is determined by GM-CSF
Luigi Dolcetti et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2010)
Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice
Mitomu Kioi et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate
Ye Zheng et al.
NATURE (2010)
Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
F. Stephen Hodi et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
Calreticulin Is the Dominant Pro-Phagocytic Signal on Multiple Human Cancers and Is Counterbalanced by CD47
Mark P. Chao et al.
SCIENCE TRANSLATIONAL MEDICINE (2010)
The regulation of IL-10 production by immune cells
Margarida Saraiva et al.
NATURE REVIEWS IMMUNOLOGY (2010)
Polarization of Tumor-Associated Neutrophil Phenotype by TGF-β: N1 versus N2 TAN
Zvi G. Fridlender et al.
CANCER CELL (2009)
Advances in Radiotherapy and Implications for the Next Century: A Historical Perspective
Philip P. Connell et al.
CANCER RESEARCH (2009)
Radiation induces an antitumour immune response to mouse melanoma
Carmen A. Perez et al.
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY (2009)
Systemic effects of local radiotherapy
Silvia C. Formenti et al.
LANCET ONCOLOGY (2009)
CD4+ Regulatory T Cells Control TH17 Responses in a Stat3-Dependent Manner
Ashutosh Chaudhry et al.
SCIENCE (2009)
Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy
Lionel Apetoh et al.
NATURE MEDICINE (2007)
Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice
Jeong M. Kim et al.
NATURE IMMUNOLOGY (2007)
Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease
Katharina Lahl et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Isoform-specific activation of latent transforming growth factor β (LTGF-β) by reactive oxygen species
Michael E. Jobling et al.
RADIATION RESEARCH (2006)
Increase of NKAG2D ligands and sensitivity to NK cell-mediated cytotoxicity of tumor cells by heat shock and ionizing radiation
Joo-Young Kim et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2006)
Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy
Eric A. Reits et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
Type I inteferon gene induction by the interferon regulatory factor family of transcription factors
Kenya Honda et al.
IMMUNITY (2006)
Combining radiotherapy and immunotherapy: A revived partnership
S Demaria et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2005)
The role of radiotherapy in cancer treatment - Estimating optimal utilization from a review of evidence-based clinical guidelines
G Delaney et al.
CANCER (2005)
Local radiation therapy of B16 melanoma tumors increases the generation of tumor antigen-specific effector cells that traffic to the tumor
AA Lugade et al.
JOURNAL OF IMMUNOLOGY (2005)
Sublethal irradiation of human tumor cells modulates phenotype resulting in enhanced killing by cytotoxic T lymphocytes
CT Garnett et al.
CANCER RESEARCH (2004)
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-β induction of transcription factor Foxp3
WJ Chen et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)