Bermuda 2.0: reflections from Santa Cruz

In February 1996, the genome community met in Bermuda to formulate principles for circulating genomic data. Although it is now 20 years since the Bermuda Principles were formulated, they continue to play a central role in shaping genomic and data-sharing practices. However, since 1996, openness has become an increasingly complex issue. This commentary seeks to articulate three core challenges data-sharing faces today.