Cyrene: a bio-based novel and sustainable solvent for organic synthesis

Dihydrolevoclucosenone (Cyrene is its market name) is a biomass-derived solvent that can be produced in only two steps from biomass, while being biodegradable, non-mutagenic and non-toxic. Its green profile combined with its physical properties makes Cyrene a plausible substitute for a number of widely used toxic organic solvents. The first attempt to assess Cyrene as a solvent dates back to 2014 and since then, numerous research groups have opted for this promising alternative. Cyrene has successfully been employed as a solvent in materials chemistry, peptide chemistry, organic synthesis and many more research fields, which are going to be discussed in the context of this review.

Automated summary

Cyrene, a biomass-derived solvent, is biodegradable, non-mutagenic and non-toxic. Since 2014, it has been increasingly used as a substitute for toxic organic solvents in various research fields.