期刊
CHEMICAL COMMUNICATIONS
卷 58, 期 72, 页码 10056-10059出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/d2cc03622c
关键词
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资金
- NSFC [52073045, 51773195, 62075217]
- Key Scientific and Technological Project of Jilin Province [20190701010GH]
- Jilin Provincial Department of Science and Technology [20210101148JC]
- Development and Reform Commission of Jilin Province [2020C035-5]
- Changchun Science and Technology Bureau [CC202110378310002101]
- EPSRC (UK) [EP/L02621X/1]
- Key Laboratory of Nanobiosensing and Nanobioanalysis at the Universities of Jilin Province
- Jilin Provincial Department of Education
The integration of AIE-active Ir(III) complex and UCNPs has resulted in a promising NIR-irradiated photosensitizer UCNPs@Ir-2-N, which shows excellent performance in killing mouse cancer cells and has potential for future applications in photodynamic therapy.
The integration of an aggregation induced emission (AIE)-active Ir(III) complex and upconversion nanoparticles (UCNPs) has achieved a NIR-irradiated photosensitizer (PS), UCNPs@Ir-2-N. This PS has satisfactory biocompatibility, excellent phototoxicity, good accumulation in cells and high O-1(2) generation ability, thereby effectively killing 4T1 mouse cancer cells in vitro. This work has potential for future photodynamic therapy (PDT) applications.
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