期刊
CHEMICAL COMMUNICATIONS
卷 58, 期 73, 页码 10237-10240出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/d2cc03081k
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The emerging synthetic development of chiral gold(III) complexes has shown new opportunities in catalysis and material science, and this study demonstrates the potential chemotherapeutic capability of a specific gold(III) complex.
Emerging synthetic development of chiral gold(III) complexes has prompted new opportunities in catalysis and material science with limited utility in biomedicine. Here, we demonstrate potential chemotherapeutic capability of [C<^>N]Au(III)Cl(R-DuPhos) (1-7) complexes, containing 1,2-bis[(2R,5R)-2,5-dialkylphospholano]benzene, which shows good stabilty, potent anticancer activity, and tolerability in mice.
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