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注意：仅列出部分参考文献，下载原文获取全部文献信息。Human cell lines for the production of recombinant proteins: on the horizon
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NEW BIOTECHNOLOGY (2015)
Use of a Small Molecule Cell Cycle Inhibitor to Control Cell Growth and Improve Specific Productivity and Product Quality of Recombinant Proteins in CHO Cell Cultures
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Effect of glucose feeding on the glycosylation quality of antibody produced by a human cell line, F2N78, in fed-batch culture
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Expression and fast preparation of biologically active recombinant human coagulation factor VII in CHO-K1 cells
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Combined in silico modeling and metabolomics analysis to characterize fed-batch CHO cell culture
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The combined effect of sodium butyrate and low culture temperature on the production, sialylation, and biological activity of an antibody produced in CHO cells
Fei Chen et al.
BIOTECHNOLOGY AND BIOPROCESS ENGINEERING (2011)
Expression of Recombinant Human Coagulation Factor VII by the Lizard Leishmania Expression System
Sina Mirzaahmadi et al.
JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY (2011)
Molecular Mechanism of Co-translational Protein Targeting by the Signal Recognition Particle
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High-level expression of functional recombinant human coagulation factor VII in insect cells
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BIOTECHNOLOGY LETTERS (2010)
Establishment of a cell line expressing recombinant factor VII and its subsequent conversion to active form FVIIa through hepsin by genetic engineering method
R. Halabian et al.
VOX SANGUINIS (2009)
Enhanced functional recombinant factor VII production by HEK 293 cells stably transfected with VKORC1 where the gamma-carboxylase inhibitor calumenin is stably suppressed by shRNA transfection
Nadeem Wajih et al.
THROMBOSIS RESEARCH (2008)
The surprising complexity of signal sequences
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TRENDS IN BIOCHEMICAL SCIENCES (2006)
Cell cycle phase dependent productivity of a recombinant Chinese hamster ovary cell line
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CYTOTECHNOLOGY (2006)
Uncoupling of cell growth and proliferation results in enhancement of productivity in p21C1P1-arrested CHO cells
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Fish as bioreactors:: Transgene expression of human coagulation factor VII in fish embryos
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MARINE BIOTECHNOLOGY (2004)
Cell growth arrest by nucleotides, nucleosides and bases as a tool for improved production of recombinant proteins
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BIOTECHNOLOGY PROGRESS (2003)
Human secretory signal peptide description by hidden Markov model and generation of a strong artificial signal peptide for secreted protein expression
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
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