期刊
ARTHRITIS RESEARCH & THERAPY
卷 24, 期 1, 页码 -出版社
BMC
DOI: 10.1186/s13075-022-02878-8
关键词
Systemic lupus erythematosus; Preventive services; Cancer screening; Osteoporosis; Vaccine; Cardiovascular risk; Diabetes; DXA; Influenza; Zoster; Pneumococcal
类别
资金
- Centers for Disease Control and Prevention (CDC) of the U.S. Department of Health and Human Services (HHS) - CDC/HHS [U01 DP006491]
- National Institute on Aging of the National Institutes of Health [R01AG034676]
- National Center for Advancing Translational Sciences (NCATS), National Institutes of Health [UL1 TR002377]
- Centers for Disease Control and Prevention [U01 DP006491]
- Rheumatology Research Foundation Scientist Development Award
- Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery
This study aimed to evaluate the utilization of preventive services in patients with systemic lupus erythematosus (SLE) compared to the general population. The results showed that SLE patients had similar rates of breast cancer screening but lower rates of cervical cancer screening compared to non-SLE individuals. Hypertension screening was higher in SLE patients, while hyperlipidemia screening was similar. Diabetes and osteoporosis screenings were more likely to be performed in SLE patients, and they also had higher rates of influenza and pneumococcal immunizations.
Background Systemic lupus erythematosus (SLE) is a disease that can lead to damage of multiple organs and, along with certain treatments, increase the risk of developing cancer, cardiovascular disease, diabetes, osteoporosis, and infections. Preventive services are particularly important in patients with SLE to mitigate the aforementioned risks. We aimed to evaluate the trends of preventive services utilization in patients with systemic lupus erythematosus, compared with non-SLE population. Methods All >= 19-year-old patients in the Lupus Midwest Network (LUMEN) registry, a population-based cohort, with SLE on January 1, 2015, were included and matched (1:1) by sex, age, race, and county to non-SLE comparators. Among both groups, we compared the rates of screenings for breast and cervical cancer, hypertension, hyperlipidemia, diabetes mellitus, and osteoporosis as well as immunizations. Results We included 440 SLE patients and 430 non-SLE comparators. The probability of breast cancer screening among women with SLE was similar to comparators (hazard ratio [HR] 1.09, 95% CI 0.85-1.39), while cervical cancer screening was lower (HR 0.75, 95% CI 0.58-0.96). Hypertension screening was higher among patients with SLE (HR 1.35, 95% CI 1.13-1.62); however, hyperlipidemia screening was similar to comparators (HR 1.16, 95% CI 0.96-1.41). Diabetes and osteoporosis screenings were more likely to be performed for SLE patients than for comparators (HR 2.46, 95% CI 2.11-2.87; and HR 3.19, 95% CI 2.31-4.41; respectively). Influenza and pneumococcal immunizations were higher among SLE patients (HR 1.31, 95% CI 1.12-1.54; and HR 2.06, 95% CI 1.38-3.09; respectively), while zoster vaccination was similar (HR 1.17, 95% CI 0.81-1.69). Conclusions The trends of utilization of preventive services by SLE patients vary according to screening or vaccine compared with the general population. Considering these differences, we demonstrate an opportunity for improvement, particularly in cervical cancer, hyperlipidemia, and osteoporosis screenings and vaccinations.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据