Anti-phytopathogenic-bacterial fatty acids from the mycelia of the edible mushroom Agaricus blazei

Five compounds including a new compound (1) were isolated from mycelia of a mushroom-forming fungus Agaricus blazei. Compound 2 was isolated from nature for the first time. Their structures were determined by the interpretation of spectroscopic data. In the bioassay examining growth inhibitory activity against phytopathogenic bacteria Clavibacter michiganensis, Burkholderia glumae, and Peptobacterium carotovorum, all the compounds showed inhibition effects on C. michiganensis. Compounds 3 and 4 also showed weak inhibitory activity against growth of B. glumae.

Automated summary

This study isolated five compounds, including a new compound, from the mycelia of the mushroom Agaricus blazei. Compound 2 was isolated for the first time from nature. The structures of these compounds were determined using spectroscopic data interpretation. In bioassays, all the compounds showed inhibition effects on the growth of Clavibacter michiganensis, while compounds 3 and 4 also exhibited weak inhibitory activity against Burkholderia glumae.