Association between vitamin D status and lifestyle factors in Brazilian women: Implications of Sun Exposure Levels, Diet, and Health

Background Vitamin D deficiency has been documented to be prevalent, even in low latitude regions; and this may be related to sun exposure behaviors. The aim of the current study was to assess the association between serum 25-hydroxyvitamin D [25(OH)D] concentrations and lifestyle-related factors in a sample of Brazilian women living at latitude 21 degrees 8' S. Methods A cross-sectional study was undertaken in 101 women aged 35 years or older in July 2019 to assess the association between 25(OH)D concentration and level of exposure to ultraviolet radiation (UVR), smoking habits, alcohol consumption, and physical activity levels. Age, body mass index (BMI), and postmenopausal status were investigated. Findings According to the slope coefficient for individual daily UVR levels, the concentration of 25(OH)D increased by 5 nmol / L for each extra Standard Erythema Dose of UVR, regardless of age and BMI (p < 0.001). Postmenopausal women had a significantly higher mean concentration of 25(OH)D (p = 0.01), higher UVR exposure (p = 0.01) and lower BMI (p = 0.005) compared with younger women, independent of other confounders including smoking, alcohol, occupation and physical activity. Interpretation Although postmenopausal women from Brazil had higher mean concentrations of 25(OH)D than younger women, more studies are necessary to understand how sun exposure and lifestyle variables interfere with these levels. These findings have important public health implications since they suggest that vitamin D deficiency in older age is not inevitable. Copyright (C) 2022 The Author(s). Published by Elsevier Ltd.

Automated summary

This study aimed to assess the association between serum 25-hydroxyvitamin D [25(OH)D] concentrations and lifestyle-related factors in Brazilian women living at latitude 21 degrees 8' S. The findings showed that higher levels of 25(OH)D concentration were associated with higher exposure to ultraviolet radiation. Postmenopausal women had higher 25(OH)D concentrations compared to younger women, suggesting that sun exposure and lifestyle variables may interfere with these levels.