Pro-senescence neddylation inhibitor combined with a senescence activated β-galactosidase prodrug to selectively target cancer cells

SIGNAL TRANSDUCTION AND TARGETED THERAPY

SPRINGERNATURE

1. National Natural Science Foundation of China [81820108022, 22177076, 22037002]
2. Innovation Program of Shanghai Municipal Education Commission [2019-01-07-00-10-E00056, 2021-01-07-00-02-E00104]
3. Scientific and Technological Innovation Action Plan of Science and Technology Commission of Shanghai [20JC1411300]
4. Shanghai Frontiers Science Center of Disease and Syndrome Biology of Inflammatory Cancer Transformation [2021KJ03-12]
5. National Thirteenth Five-Year Science and Technology Major Special Project for New Drug and Development [2017ZX09304001]
6. Shanghai Frontier Science Research Base of Optogenetic Techniques for Cell Metabolism [2021 Sci Tech 03-28]
7. Innovative Research Team of High-level Local Universities in Shanghai
8. Chinese Special Fund for State Key Laboratory of Bioreactor Engineering [2060204]