相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。COVID-19: A Case for Inhibiting NLRP3 Inflammasome, Suppression of Inflammation with Curcumin?
Ali Saeedi-Boroujeni et al.
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2021)
Strategies for Targeting the NLRP3 Inflammasome in the Clinical and Preclinical Space
Adam G. Schwaid et al.
JOURNAL OF MEDICINAL CHEMISTRY (2021)
Development of Novel Tetrahydroquinoline Inhibitors of NLRP3 Inflammasome for Potential Treatment of DSS-Induced Mouse Colitis
Zhen Dai et al.
JOURNAL OF MEDICINAL CHEMISTRY (2021)
Structure-Based Design of Selective LONP1 Inhibitors for Probing In Vitro Biology
Laura J. Kingsley et al.
JOURNAL OF MEDICINAL CHEMISTRY (2021)
The ubiquitylation of IL-1β limits its cleavage by caspase-1 and targets it for proteasomal degradation
Swarna L. Vijayaraj et al.
NATURE COMMUNICATIONS (2021)
Discovery of chalcone analogues as novel NLRP3 inflammasome inhibitors with potent anti-inflammation activities
Cheng Zhang et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2021)
NLRP3 Ubiquitination-A New Approach to Target NLRP3 Inflammasome Activation
Mahbuba Akther et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Structure-Based Optimization and Discovery of M3258, a Specific Inhibitor of the Immunoproteasome Subunit LMP7 (β5i)
Markus Klein et al.
JOURNAL OF MEDICINAL CHEMISTRY (2021)
Sequential ubiquitination of NLRP3 by RNF125 and Cbl-b limits inflammasome activation and endotoxemia
Juan Tang et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2020)
Discovery of Novel Peptidomimetic Boronate ClpP Inhibitors with Noncanonical Enzyme Mechanism as Potent Virulence Blockers in Vitro and in Vivo
Yuan Ju et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
The long and winding road in pharmaceutical development of canakinumab from rare genetic autoinflammatory syndromes to myocardial infarction and cancer
Hermann Gram
PHARMACOLOGICAL RESEARCH (2020)
Benzyl isothiocyanate ameliorates high-fat/cholesterol/cholic acid diet-induced nonalcoholic steatohepatitis through inhibiting cholesterol crystal-activated NLRP3 inflammasome in Kupffer cells
Haw-Wen Chen et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2020)
Discovery of Peptide Boronate Derivatives as Histone Deacetylase and Proteasome Dual Inhibitors for Overcoming Bortezomib Resistance of Multiple Myeloma
Yi Zhou et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
Palmitic acid stimulates NLRP3 inflammasome activation through TLR4-NF-κB signal pathway in hepatic stellate cells
Zhixia Dong et al.
ANNALS OF TRANSLATIONAL MEDICINE (2020)
Cbl Negatively Regulates NLRP3 Inflammasome Activation through GLUT1-Dependent Glycolysis Inhibition
Hsin-Chung Lin et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Blocking of Transient Receptor Potential Vanilloid 1 (TRPV1) promotes terminal mitophagy in multiple myeloma, disturbing calcium homeostasis and targeting ubiquitin pathway and bortezomib-induced unfolded protein response
Katia Beider et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2020)
UAF1 deubiquitinase complexes facilitate NLRP3 inflammasome activation by promoting NLRP3 expression
Hui Song et al.
NATURE COMMUNICATIONS (2020)
ABRO1 promotes NLRP3 inflammasome activation through regulation of NLRP3 deubiquitination
Guangming Ren et al.
EMBO JOURNAL (2019)
Proteasome Activation as a New Therapeutic Approach To Target Proteotoxic Disorders
Evert Njomen et al.
JOURNAL OF MEDICINAL CHEMISTRY (2019)
MCC950 directly targets the NLRP3 ATP- hydrolysis motif for inflammasome inhibition
Rebecca C. Coll et al.
NATURE CHEMICAL BIOLOGY (2019)
Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome
Humayun Sharif et al.
NATURE (2019)
Pharmacological inhibition of the NLRP3 inflammasome reduces blood pressure, renal damage, and dysfunction in salt-sensitive hypertension
Shalini M. Krishnan et al.
CARDIOVASCULAR RESEARCH (2019)
Palmatine attenuated dextran sulfate sodium (DSS)-induced colitis via promoting mitophagy-mediated NLRP3 inflammasome inactivation
Chu-Tian Mai et al.
MOLECULAR IMMUNOLOGY (2019)
The NLRP3 inflammasome: molecular activation and regulation to therapeutics
Karen V. Swanson et al.
NATURE REVIEWS IMMUNOLOGY (2019)
Targeting the NLRP3 inflammasome in inflammatory diseases
Matthew S. J. Mangan et al.
NATURE REVIEWS DRUG DISCOVERY (2018)
NLRP3 lacking the leucine-rich repeat domain can be fully activated via the canonical inflammasome pathway
Iva Hafner-Bratkovic et al.
NATURE COMMUNICATIONS (2018)
NLRP3 inflammasome: a promising target in ischemic stroke
Li Gao et al.
INFLAMMATION RESEARCH (2017)
Senegenin exerts anti-depression effect in mice induced by chronic unpredictable mild stress via inhibition of NF-κB regulating NLRP3 signal pathway
Hongwei Li et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2017)
Development of an Acrylate Derivative Targeting the NLRP3 Inflammasome for the Treatment of Inflammatory Bowel Disease
Mattia Cocco et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
Revisiting the Role of Interleukin-1 Pathway in Osteoarthritis: Interleukin-1α and-1β, and NLRP3 Inflammasome Are Not Involved in the Pathological Features of the Murine Menisectomy Model of Osteoarthritis
Sonia Nasi et al.
FRONTIERS IN PHARMACOLOGY (2017)
Boron-Based Inhibitors of the NLRP3 Inflammasome
Alex G. Baldwin et al.
CELL CHEMICAL BIOLOGY (2017)
NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux
Yuan He et al.
NATURE (2016)
Targeting ASC in NLRP3 inflammasome by caffeic acid phenethyl ester: a novel strategy to treat acute gout
Hye Eun Lee et al.
SCIENTIFIC REPORTS (2016)
Inflammasomes: mechanism of assembly, regulation and signalling
Petr Broz et al.
NATURE REVIEWS IMMUNOLOGY (2016)
A20 Restricts Ubiquitination of Pro-Interleukin-1β Protein Complexes and Suppresses NLRP3 Inflammasome Activity
Bao H. Duong et al.
IMMUNITY (2015)
Initiation and perpetuation of NLRP3 inflammasome activation and assembly
Eric I. Elliott et al.
IMMUNOLOGICAL REVIEWS (2015)
Neutrophil IL-1β Processing Induced by Pneumolysin Is Mediated by the NLRP3/ASC Inflammasome and Caspase-1 Activation and Is Dependent on K+ Efflux
Mausita Karmakar et al.
JOURNAL OF IMMUNOLOGY (2015)
A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
Rebecca C. Coll et al.
NATURE MEDICINE (2015)
Immuno- and Constitutive Proteasome Crystal Structures Reveal Differences in Substrate and Inhibitor Specificity
Eva M. Huber et al.
CELL (2012)
Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases
Charles A. Dinarello et al.
NATURE REVIEWS DRUG DISCOVERY (2012)
Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome
Christian Bauer et al.
GUT (2010)
Synthesis, in Vitro and in Vivo Biological Evaluation, and Comprehensive Understanding of Structure-Activity Relationships of Dipeptidyl Boronic Acid Proteasome Inhibitors Constructed from β-Amino Acids
Yongqiang Zhu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Design, synthesis and biological evaluation of tripeptide boronic acid proteasome inhibitors
Yongqiang Zhu et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2009)
Anakinra for Rheumatoid Arthritis: A Systematic Review
Marty Mertens et al.
JOURNAL OF RHEUMATOLOGY (2009)
Targeting the NF-kappa B signaling pathway in Notch1-induced T-cell leukemia
Tomas Vilimas et al.
NATURE MEDICINE (2007)