期刊
INTERNATIONAL JOURNAL OF PUBLIC HEALTH
卷 67, 期 -, 页码 -出版社
FRONTIERS MEDIA SA
DOI: 10.3389/ijph.2022.1604939
关键词
incidence; comorbidity; asthma; napping; sleep duration
资金
- Natural Science Foundation of Hubei province CN [2018CFB643]
- National nature science foundation of China [81970082]
- Behavioral and Social Research division of the National Institute on Aging of the National Institute of Health [1-R21-AG031372-01, 1-R01-AG037031-01, 3-R01AG037031-03S1]
- Natural Science Foundation of China [70773002, 70910107022, 71130002]
- World Bank [7145915, 7159234]
- Peking University
This study aimed to investigate the associations between comorbidity profiles, night sleep duration, and napping duration trajectories with incident asthma in Chinese adults. The results showed that a dominant short night sleep duration trajectory potentially increases the risk of new-onset asthma.
Objectives: We aim to determine whether comorbidity profiles, night sleep duration, and napping duration trajectories were associated with incident asthma in Chinese adults. Methods: A total of 7,655 community-dwelling individuals were included in this study. Latent class/profile analysis(LCA/LPA) identified comorbidity profiles, night sleep duration, and napping duration trajectories. A generalized additive model with binomial regression assessed the associations between incident asthma with sleep trajectories. Results: During a 7-year follow-up period, 205 individuals were newly diagnosed with asthma. LPA identified four trajectories of night sleep duration: dominant short (n = 2,480), dominant healthy-long (n = 1,405), long decreasing (n = 1875), and short increasing (n = 1895). We also found three trajectories of napping duration: short increasing (n = 3,746), stable normal (n = 1,379), and long decreasing (n = 2,530). We found three comorbidity profiles: dominant heart diseases or risks (n = 766), multiple disorders (n = 758), and minimal or least disorders (n = 6,131). Compared with dominant short night sleep duration, three other trajectories were associated with significantly decreasing incident asthma. Minimal or least disorders profile was associated with a significant reduction of new-onset asthma than two other comorbidity profiles in dominant short night sleep duration. Conclusion: Our findings suggested that a dominant short night sleep duration trajectory potentially increases incident asthma in Chinese adults.
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