Phthaloylation of amines, hydrazines, and hydrazides by N-substituted phthalimides using recyclable sulfated polyborate

An efficient, fast, and environmentally gentle protocol for phthaloylation of amines, hydrazines and hydrazides via transamidation is described. The current research focuses on the phthaloylation of alicyclic, aliphatic, aromatic, heterocyclic amines, hydrazines, and hydrazides. Reaction with N-substituted phthalimides was completed in about 30 minutes at 70 degrees C in DMSO as a solvent, resulting in higher yield of products, ease of workup, and recyclability of catalyst. In addition to this, transamidation of cinnamamide and benzamide was also successfully achieved.

Automated summary

An efficient and fast protocol for the phthaloylation of amines, hydrazines, and hydrazides via transamidation is described. The reaction can be completed in about 30 minutes at 70 degrees C in DMSO as a solvent, resulting in higher yield of products, easy workup, and recyclability of the catalyst. In addition, successful transamidation of cinnamamide and benzamide was also achieved.