Dedifferentiated liposarcoma found in ovary: A rare case report

Rationale: Dedifferentiated liposarcoma (DL) of the ovary is a rare mesenchymal tumor which is difficult to diagnose before surgery. The diagnose of DL was depended on the morphology, Immunohistochemical stains, and fluorescence in situ hybridization after the complete surgical resection. Patient concerns: We report a case of 63-year-old postmenopausal female who presented with a large pelvic mass and was initially thought to be an original ovarian tumor. However, it was subsequently considered to be a DL arising from the mesentery and developing in ovary. Diagnosis: Ovarian DL. Interventions: Bilateral salpingo-oophorectomy. Outcomes: Until now, there is no recurrence symptoms represented in the patient after surgery for 12 months. Lessons: DL happening in ovary is rare. In this case, the exact origin of the mass still remains ambiguous because of the lack of morphological evidence. Although retroperitoneum is the most common area of DL origin, we for long suspect that the mass was initially derived from mesentery and developed in ovary. A long-term may help confirm the exact origin of the tumor. Complete surgical resection plays an important role in the treatment.

Automated summary

Dedifferentiated liposarcoma (DL) of the ovary is a rare mesenchymal tumor that is challenging to diagnose preoperatively. The diagnosis of DL typically relies on morphological evidence, immunohistochemical stains, and fluorescence in situ hybridization. We present a case of a patient initially thought to have a primary ovarian tumor but was eventually diagnosed with DL arising from the mesentery and developing in the ovary. The patient has remained asymptomatic without recurrence for 12 months following bilateral salpingo-oophorectomy.