期刊
ACS APPLIED BIO MATERIALS
卷 -, 期 -, 页码 -出版社
AMER CHEMICAL SOC
DOI: 10.1021/acsabm.2c00248
关键词
Ag nanocomposite; anodized aluminum; high-touch surfaces; polymethylhydrosiloxane; quaternary ammonium salt
资金
- Fonds de recherche du Qu?bec -- Nature et technologies (FRQNT) [2018-LU-210883]
In this study, a sol-gel process was used to incorporate silver and quaternary ammonium salt bactericides in a polymethylhydrosiloxane matrix. The resulting Ag-PMHS-QUAT nanocomposite was coated on anodized aluminum using ultrasound-assisted deposition. The nanocomposite exhibited superior antibacterial property, reducing bacterial count significantly.
Multidrug-resistant bacteria are known to survive on high-touch surfaces for days, weeks, and months, contributing to the rise in nosocomial infections. Inducing antibacterial property in such surfaces can presumably reduce the overall microbial burden and subsequent nosocomial infections in hygiene critical environments. In the present study, a one-pot sol-gel process has been deployed to incorporate silver (Ag) and quaternary ammonium salt (QUAT) bactericides in a polymethylhydrosiloxane (PMHS) matrix. The Ag-PMHS-QUAT nanocomposite was coated on anodized aluminum (AAO/Al) by a simple ultrasound-assisted deposition process. The morphological features and chemical composition of the Ag-PMHS-QUAT nanocomposite have been characterized using SEM, XRD spectroscopy, and attenuated total reflection-Fourier transform infrared spectroscopy (ATR-FTIR) to confirm the formation of Ag-QUAT nanocomposites within the polymeric network of PMHS. The Ag-PMHS-QUAT nanocomposite coating on anodized aluminum oxide (AAO/Al) coupon exhibited superior antibacterial property with a 6-log bacterial reduction compared to the 5-log reduction for the commercially available antimicrobial copper coupon.
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