4.5 Article

Different N-Glycosylation Sites Reduce the Activity of Recombinant DSPAα2

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models

Mihaly Varadi et al.

Summary: AlphaFold DB is an openly accessible database with high-accuracy protein-structure predictions, powered by DeepMind's AlphaFold v2.0. It provides programmatic access to a vast number of predicted structures and is expanding to cover more sequences.

NUCLEIC ACIDS RESEARCH (2022)

Article Biochemistry & Molecular Biology

N-Glycosylation as a Tool to Study Antithrombin Secretion, Conformation, and Function

Sonia Aguila et al.

Summary: N-linked glycosylation is crucial in protein post-translational modification, and can enhance protein half-lives. The study revealed key regions for antithrombin secretion and could potentially apply to all serpins.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Multidisciplinary Sciences

Highly accurate protein structure prediction with AlphaFold

John Jumper et al.

Summary: Proteins are essential for life, and accurate prediction of their structures is a crucial research problem. Current experimental methods are time-consuming, highlighting the need for accurate computational approaches to address the gap in structural coverage. Despite recent progress, existing methods fall short of atomic accuracy in protein structure prediction.

NATURE (2021)

Article Biochemical Research Methods

The effect of N-glycosylation on the expression of the tetanus toxin fragment C in Pichia pastoris

Nan Wang et al.

PROTEIN EXPRESSION AND PURIFICATION (2020)

Article Multidisciplinary Sciences

Revealing the intrinsic nature of the mid-gap defects in amorphous Ge2Sb2Te5

Konstantinos Konstantinou et al.

NATURE COMMUNICATIONS (2019)

Review Pharmacology & Pharmacy

Biochemical and physiological importance of the CYP26 retinoic acid hydroxylases

Nina Isoherranen et al.

PHARMACOLOGY & THERAPEUTICS (2019)

Article Biochemistry & Molecular Biology

Enhanced breast cancer progression by mutant p53 is inhibited by the circular RNA circ-Ccnb1

Ling Fang et al.

CELL DEATH AND DIFFERENTIATION (2018)

Article Neurosciences

Targeting Neuroblastoma Cell Surface Proteins: Recommendations for Homology Modeling of hNET, ALK, and TrkB

Yazan Haddad et al.

FRONTIERS IN MOLECULAR NEUROSCIENCE (2017)

Article Biochemistry & Molecular Biology

Chromatin structure-dependent conformations of the H1 CTD

He Fang et al.

NUCLEIC ACIDS RESEARCH (2016)

Article Biochemistry & Molecular Biology

Assembly and analysis of eukaryotic Argonaute-RNA complexes in microRNA-target recognition

Hin Hark Gan et al.

NUCLEIC ACIDS RESEARCH (2015)

Article Biotechnology & Applied Microbiology

The role of N-glycosylation sites in the activity, stability, and expression of the recombinant elastase expressed by Pichia pastoris

Minghai Han et al.

ENZYME AND MICROBIAL TECHNOLOGY (2014)

Article Multidisciplinary Sciences

Agonist-bound structure of the human P2Y12 receptor

Jin Zhang et al.

NATURE (2014)

Article Multidisciplinary Sciences

Structure of the human P2Y12 receptor in complex with an antithrombotic drug

Kaihua Zhang et al.

NATURE (2014)

Article Multidisciplinary Sciences

Folding pathway of a multidomain protein depends on its topology of domain connectivity

Takashi Inanami et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Review Pharmacology & Pharmacy

Serine-proteases as plasminogen activators in terms of fibrinolysis

Martin Flemmig et al.

JOURNAL OF PHARMACY AND PHARMACOLOGY (2012)

Article Pharmacology & Pharmacy

N-Glycosylation plays a role in protein folding of human UGT1A9

Miki Nakajima et al.

BIOCHEMICAL PHARMACOLOGY (2010)

Article Multidisciplinary Sciences

Effect of glycosylation on protein folding: A close look at thermodynamic stabilization

Dalit Shental-Bechor et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Biochemical Research Methods

Recombinant therapeutic proteins: Production platforms and challenges

Theo Dingermann

Biotechnology Journal (2007)

Review Biochemical Research Methods

Glycosylation engineering in yeast: the advent of fully humanized yeast

Stephen R. Hamilton et al.

CURRENT OPINION IN BIOTECHNOLOGY (2007)

Review Chemistry, Medicinal

Glycoengineering: The effect of glycosylation on the properties of therapeutic proteins

AM Sinclair et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2005)

Article Chemistry, Organic

Protein glycosylation: New challenges and opportunities

CH Wong

JOURNAL OF ORGANIC CHEMISTRY (2005)

Review Biochemistry & Molecular Biology

Role of glycosylation indevelopment

RS Haltiwanger et al.

ANNUAL REVIEW OF BIOCHEMISTRY (2004)

Article Biochemistry & Molecular Biology

N-linked glycans direct the cotranslational folding pathway of influenza hemagglutinin

R Daniels et al.

MOLECULAR CELL (2003)

Article Biotechnology & Applied Microbiology

Genetic engineering of Pichia pastoris to humanize N-glycosylation of proteins

MJ Koury

TRENDS IN BIOTECHNOLOGY (2003)

Review Multidisciplinary Sciences

Intracellular functions of N-linked glycans

A Helenius et al.

SCIENCE (2001)

Review Biochemistry & Molecular Biology

Recombinant protein expression in Pichia pastoris

JM Cregg et al.

MOLECULAR BIOTECHNOLOGY (2000)