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Lei Wang et al.
CARCINOGENESIS (2014)
Topoisomerase 2 beta: A Promising Molecular Target for Primary Prevention of Anthracycline-Induced Cardiotoxicity
P. Vejpongsa et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2014)
Ellagic Acid Induces Apoptosis in TSGH8301 Human Bladder Cancer Cells Through the Endoplasmic Reticulum Stress- and Mitochondria-Dependent Signaling Pathways
Chin-Chih Ho et al.
ENVIRONMENTAL TOXICOLOGY (2014)
Cisplatin in cancer therapy: Molecular mechanisms of action
Shaloam Dasari et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2014)
Risk of cardiovascular toxicities in patients with solid tumors treated with sorafenib: an updated systematic review and meta-analysis
Omar Abdel-Rahman et al.
FUTURE ONCOLOGY (2014)
NOVEL DEVELOPMENTS IN THE USE OF ANTIMETABOLITES
Godefridus J. Peters
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS (2014)
Astragalus Polysaccharide Suppresses Doxorubicin-Induced Cardiotoxicity by Regulating the PI3k/Akt and p38MAPK Pathways
Yuan Cao et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2014)
Nrf2 Deficiency Exaggerates Doxorubicin-Induced Cardiotoxicity and Cardiac Dysfunction
Siying Li et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2014)
A systematic review of the pathophysiology of 5-fluorouracil-induced cardiotoxicity
Anne Polk et al.
BMC PHARMACOLOGY & TOXICOLOGY (2014)
Cardio-miRNAs and onco-miRNAs: circulating miRNA-based diagnostics for non-cancerous and cancerous diseases
Masaru Katoh
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2014)
Adverse Effects of Doxorubicin and Its Metabolic Product on Cardiac RyR2 and SERCA2A
Amy D. Hanna et al.
MOLECULAR PHARMACOLOGY (2014)
Acute changes in endothelial function with cisplatin among germ cell tumor (GCT) patients (Pts).
Darren Richard Feldman et al.
JOURNAL OF CLINICAL ONCOLOGY (2014)
Cardioprotective potential of N,α-L-rhamnopyranosyl vincosamide, an indole alkaloid, isolated from the leaves of Moringa oleifera in isoproterenol induced cardiotoxic rats: In vivo and in vitro studies
Sunanda Panda et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2013)
Polyphenols, Inflammation, and Cardiovascular Disease
Christy C. Tangney et al.
CURRENT ATHEROSCLEROSIS REPORTS (2013)
Cardioprotective effect of Saraca indica against cyclophosphamide induced cardiotoxicity in rats: A biochemical, electrocardiographic and histopathological study
A. H. M. Viswanatha Swamy et al.
INDIAN JOURNAL OF PHARMACOLOGY (2013)
Patients With Heart Failure Have an Increased Risk of Incident Cancer
Tal Hasin et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2013)
Protective effect of Hypericum hircinum on doxorubicin-induced cardiotoxicity in rats
Sudeep Shah et al.
NATURAL PRODUCT RESEARCH (2013)
ULK1 targets Beclin-1 in autophagy
Volodymyr Y. Nazarko et al.
NATURE CELL BIOLOGY (2013)
Targeted cancer therapy - Are the days of systemic chemotherapy numbered?
Won Duk Joo et al.
MATURITAS (2013)
Does spironolactone ameliorate trastuzumab-induced cardiac toxicity?
Guler Yavas et al.
MEDICAL HYPOTHESES (2013)
Antiangiogenic Effects of P-Coumaric Acid in Human Endothelial Cells
Chang-Seok Kong et al.
PHYTOTHERAPY RESEARCH (2013)
Trastuzumab Alters the Expression of Genes Essential for Cardiac Function and Induces Ultrastructural Changes of Cardiomyocytes in Mice
M. Khair ElZarrad et al.
PLOS ONE (2013)
Cytosolic p53 inhibits Parkin-mediated mitophagy and promotes mitochondrial dysfunction in the mouse heart
Atsushi Hoshino et al.
NATURE COMMUNICATIONS (2013)
Anti-cancer potential of flavonoids: recent trends and future perspectives
Priya Batra et al.
3 BIOTECH (2013)
Cardiovascular toxicity induced by chemotherapy, targeted agents and radiotherapy: ESMO Clinical Practice Guidelines
G. Curigliano et al.
ANNALS OF ONCOLOGY (2012)
Venous thromboembolism and cancer
Donald G. MacLellan et al.
ANZ JOURNAL OF SURGERY (2012)
Anticancer polysaccharides from natural resources: A review of recent research
Aizhen Zong et al.
CARBOHYDRATE POLYMERS (2012)
Breast Cancer Treatment and Adverse Cardiac Events: What Are the Molecular Mechanisms?
Laura Roca-Alonso et al.
CARDIOLOGY (2012)
Future perspectives of personalized medicine in traditional Chinese medicine: A systems biology approach
Aihua Zhang et al.
COMPLEMENTARY THERAPIES IN MEDICINE (2012)
Flavonoid-rich apples and nitrate-rich spinach augment nitric oxide status and improve endothelial function in healthy men and women: a randomized controlled trial
Catherine P. Bondonno et al.
FREE RADICAL BIOLOGY AND MEDICINE (2012)
Ionizing radiation induces mitochondrial reactive oxygen species production accompanied by upregulation of mitochondrial electron transport chain function and mitochondrial content under control of the cell cycle checkpoint
Tohru Yamamori et al.
FREE RADICAL BIOLOGY AND MEDICINE (2012)
Rac1 Protein Signaling Is Required for DNA Damage Response Stimulated by Topoisomerase II Poisons
Stefanie C. Huelsenbeck et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Identification of the molecular basis of doxorubicin-induced cardiotoxicity
Sui Zhang et al.
NATURE MEDICINE (2012)
Protective effect of methotrexate in patients with rheumatoid arthritis and cardiovascular comorbidity
Jonathan L. Marks et al.
THERAPEUTIC ADVANCES IN MUSCULOSKELETAL DISEASE (2012)
Chronic Anthracycline Cardiotoxicity: Molecular and Functional Analysis with Focus on Nuclear Factor Erythroid 2-Related Factor 2 and Mitochondrial Biogenesis Pathways
Eduard Jirkovsky et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2012)
Botanical Flavonoids on Coronary Heart Disease
Chong-Zhi Wang et al.
AMERICAN JOURNAL OF CHINESE MEDICINE (2011)
The relative contribution of pro-apoptotic p53-target genes in the triggering of apoptosis following DNA damage in vitro and in vivo
Kageaki Kuribayashi et al.
CELL CYCLE (2011)
A Novel Preclinical Strategy for Identifying Cardiotoxic Kinase Inhibitors and Mechanisms of Cardiotoxicity
Hui Cheng et al.
CIRCULATION RESEARCH (2011)
Cisplatin-induced cardiotoxicity Mechanisms and cardioprotective strategies
El-Sayed E. El-Awady et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2011)
Natural and synthetic saponin adjuvant QS-21 for vaccines against cancer
Govind Ragupathi et al.
EXPERT REVIEW OF VACCINES (2011)
Incidence and Risk of Congestive Heart Failure in Patients With Renal and Nonrenal Cell Carcinoma Treated With Sunitinib
Christopher J. Richards et al.
JOURNAL OF CLINICAL ONCOLOGY (2011)
Berberine Attenuates Doxorubicin-induced Cardiotoxicity in Mice
X. Zhao et al.
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH (2011)
CaMKII-dependent SR Ca leak contributes to doxorubicin-induced impaired Ca handling in isolated cardiac myocytes
Can M. Sag et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2011)
Recurrent myocardial infarction associated with gefitinib therapy
Donald R. Lynch et al.
JOURNAL OF THROMBOSIS AND THROMBOLYSIS (2011)
New Insights into Molecular Mechanisms of Sunitinib-Associated Side Effects
Guadalupe Aparicio-Gallego et al.
MOLECULAR CANCER THERAPEUTICS (2011)
In vitro and in vivo study on the antioxidant activity of dexrazoxane
Fabio Galetta et al.
BIOMEDICINE & PHARMACOTHERAPY (2010)
2009 Focused Update Incorporated Into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines (vol 119, pg e391, 2009)
Hunt
CIRCULATION (2010)
Cisplatin compromises myocardial contractile function and mitochondrial ultrastructure: Role of endoplasmic reticulum stress
Heng Ma et al.
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2010)
PD-1 deficiency results in the development of fatal myocarditis in MRL mice
Jian Wang et al.
INTERNATIONAL IMMUNOLOGY (2010)
Transcription Factor GATA4 Inhibits Doxorubicin-induced Autophagy and Cardiomyocyte Death
Satoru Kobayashi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Autophagy plays an important role in Sunitinib-mediated cell death in H9c2 cardiac muscle cells
Yuqin Zhao et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2010)
Stabilization of mitochondrial membrane potential prevents doxorubicin-induced cardiotoxicity in isolated rat heart
David Montaigne et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2010)
Effects of methotrexate on the developments of heart and vessel in zebrafish
Shuna Sun et al.
ACTA BIOCHIMICA ET BIOPHYSICA SINICA (2009)
Enzymology of Purine and Pyrimidine Antimetabolites Used in the Treatment of Cancer
William B. Parker
CHEMICAL REVIEWS (2009)
Blockade of the erbB2 Receptor Induces Cardiomyocyte Death through Mitochondrial and Reactive Oxygen Species-dependent Pathways
Leo I. Gordon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Fulminant fatal cardiotoxicity following cyclophosphamide therapy
Minako Katayama et al.
JOURNAL OF CARDIOLOGY (2009)
PGC-1α and ERRα target gene downregulation is a signature of the failing human heart
Smita Sihag et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2009)
Cardiovascular Complications of Cancer Therapy Incidence, Pathogenesis, Diagnosis, and Management
Edward T. H. Yeh et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2009)
Testing the inflammatory hypothesis of atherothrombosis: scientific rationale for the cardiovascular inflammation reduction trial (CIRT)
Paul M. Ridker
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2009)
Decreased Oxygen Transfer Capacity of Erythrocytes as a Cause of 5-Fluorouracil Related Ischemia
Ivan Spasojevic et al.
MOLECULES (2009)
Cyclophosphamide and cancer: golden anniversary
Ashkan Emadi et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2009)
Effects of Methotrexate on Plasma Cytokines and Cardiac Remodeling and Function in Postmyocarditis Rats
Zhengang Zhang et al.
MEDIATORS OF INFLAMMATION (2009)
Salvianolic acids prevent acute doxorubicin cardiotoxicity in mice through suppression of oxidative stress
Baohong Jiang et al.
FOOD AND CHEMICAL TOXICOLOGY (2008)
Prevention and treatment of functional and structural radiation injury in the rat heart by pentoxifylline and alpha-tocopherol
Marjan Boerma et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2008)
Programmed death ligand 1 regulates a critical checkpoint for autoimmune myocarditis and pneumonitis in MRL mice
Julie A. Lucas et al.
JOURNAL OF IMMUNOLOGY (2008)
The cardio-protecting agent and topoisomerase II catalytic inhibitor sobuzoxane enhances doxorubicin-DNA adduct mediated cytotoxicity
Lonnie P. Swift et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2008)
Cardiotoxicity associated with tyrosine kinase inhibitor sunitinib
Tammy F. Chu et al.
LANCET (2007)
Mechanisms of acrolein-induced myocardial dysfunction: implications for environmental and endogenous aldehyde exposure
Jianzhu Luo et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2007)
Protective effect of Lycium barbarum on doxorubicin-induced cardiotoxicity
Yan-Fei Xin et al.
PHYTOTHERAPY RESEARCH (2007)
Induction of mitochondrial biogenesis is a maladaptive mechanism in mitochondrial cardiomyopathies
Mariangela Sebastiani et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2007)
Topoisomerase IIβ-Mediated DNA double-strand breaks:: Implications in doxorubicin cardiotoxicity and prevention by dexrazoxane
Yi Lisa Lyu et al.
CANCER RESEARCH (2007)
Adjuvant trastuzumab in the treatment of her-2-positive early breast cancer: a meta-analysis of published randomized trials
Gustavo A. Viani et al.
BMC CANCER (2007)
Protective effects of carvedilol against anthracycline-induced cardiomyopathy
Nihat Kalay et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2006)
A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure
Eva van Rooij et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Multicenter randomized phase III study of the cardioprotective effect of dexrazoxane (Cardioxane®) in advanced/metastatic breast cancer patients treated with anthracycline-based chemotherapy
M Marty et al.
ANNALS OF ONCOLOGY (2006)
DNA damage-induced cell death by apoptosis
Wynand P. Roos et al.
TRENDS IN MOLECULAR MEDICINE (2006)
Protecting against anthracycline-induced myocardial damage: a review of the most promising strategies
KA Wouters et al.
BRITISH JOURNAL OF HAEMATOLOGY (2005)
Pathology of radiation and anthracycline cardiotoxicity
GJ Berry et al.
PEDIATRIC BLOOD & CANCER (2005)
Dietary vitamin E decreases doxorubicin-induced oxidative stress without preventing mitochondrial dysfunction
JM Berthiaume et al.
CARDIOVASCULAR TOXICOLOGY (2005)
Antarth, a polyherbal preparation protects against the doxorubicin-induced toxicity without compromising its antineoplastic activity
GC Jagetia et al.
PHYTOTHERAPY RESEARCH (2005)
Micro albuminuria, decreased fibrinolysis, and inflammation as early signs of atherosclerosis in long-term survivors of disseminated testicular cancer
J Nuver et al.
EUROPEAN JOURNAL OF CANCER (2004)
Selenium and high dose vitamin E administration protects cisplatin-induced oxidative damage to renal, liver and lens tissues in rats
M Naziroglu et al.
TOXICOLOGY (2004)
Interaction model for anthracycline activity against DNA topoisomerase II
S Moro et al.
BIOCHEMISTRY (2004)
Carvedilol-mediated antioxidant protection against doxorubicin-induced cardiac mitochondrial toxicity
PJ Oliveira et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2004)
Carvedilol prevents doxorubicin-induced free radical release and apoptosis in cardiomyocytes in vitro
P Spallarossa et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2004)
Congestive heart failure in patients treated with doxorubicin - A retrospective analysis of three trials
SM Swain et al.
CANCER (2003)
Anthracycline cardiotoxicity in transgenic mice overexpressing SR Ca2+-ATPase
BE Burke et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction
B Pitt et al.
NEW ENGLAND JOURNAL OF MEDICINE (2003)
Effect of coenzyme Q10 supplementation on mitochondrial function after myocardial ischemia reperfusion
JA Crestanello et al.
JOURNAL OF SURGICAL RESEARCH (2002)
Potential protective role of angiotensin-converting enzyme inhibitors captopril and enalapril against adriamycin-induced acute cardiac and hepatic toxicity in rats
MAA El-Aziz et al.
JOURNAL OF APPLIED TOXICOLOGY (2001)
Evidence for health benefits of plant phenols: local or systemic effects?
PCH Hollman
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE (2001)
2000 update of recommendations for the use of hematopoietic colony-stimulating factors: Evidence-based, clinical practice guidelines
H Ozer et al.
JOURNAL OF CLINICAL ONCOLOGY (2000)