3.8 Review

Novel Designer Benzodiazepines: Comprehensive Review of Evolving Clinical and Adverse Effects

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Substance Abuse

Challenges of Diagnosing and Managing Designer Benzodiazepine Dependence and Withdrawal: A Case Report

Linda Peng et al.

Summary: This article presents a case of sedative-hypnotic use disorder related to designer benzodiazepines (DBZDs) and highlights the challenges in clinical management. The usage of DBZDs is often under-recognized due to their unique properties and is associated with difficulties in diagnosis and treatment.

JOURNAL OF ADDICTION MEDICINE (2022)

Article Chemistry, Analytical

Driving Impairment Cases Involving Etizolam and Flubromazolam

Timothy P. Rohrig et al.

Summary: This study revealed the presence of designer benzodiazepines such as etizolam and flubromazolam in impaired drivers. The low concentrations of these drugs may go undetected through routine testing, highlighting the need to include them in validated analytical methods. This underscores the importance of monitoring emerging novel psychoactive substances to enhance public safety.

JOURNAL OF ANALYTICAL TOXICOLOGY (2021)

Review Environmental Sciences

Benzodiazepines: Their Use either as Essential Medicines or as Toxics Substances

Edilma Sanabria et al.

Summary: This review provides a comprehensive overview of the nature, pharmacological differences, and responsible use of benzodiazepines, as well as efforts to reduce their adverse effects.

TOXICS (2021)

Article Clinical Neurology

Catatonia: Clinical Overview of the Diagnosis, Treatment, and Clinical Challenges

Amber N. Edinoff et al.

Summary: Catatonia is a syndrome associated with various mental illness disorders and some medical conditions, with treatments often involving the use of benzodiazepines and electroconvulsive therapy. The pathophysiology of catatonia involves aberrant neuronal activity, defective neurotransmitter regulation, and impaired oligodendrocyte function.

NEUROLOGY INTERNATIONAL (2021)

Article Clinical Neurology

Benzodiazepines: Uses, Dangers, and Clinical Considerations

Amber N. Edinoff et al.

Summary: Benzodiazepines are widely prescribed psychoactive drugs known for their sedative effects on the central nervous system. Despite their effectiveness in treating various conditions, they have a high potential for addiction and withdrawal symptoms, requiring careful tapering of the medication. Future research is needed to explore alternative methods for treating BZD withdrawal due to the increasing number of individuals seeking treatment for BZD dependence in the United States.

NEUROLOGY INTERNATIONAL (2021)

Review Neurosciences

'New/Designer Benzodiazepines': An Analysis of the Literature and Psychonauts' Trip Reports

Laura Orsolini et al.

CURRENT NEUROPHARMACOLOGY (2020)

Article Medicine, Legal

Clonazolam a new designer benzodiazepine intoxication confirmed by blood concentration

Karina Sommerfeld-Klatta et al.

FORENSIC SCIENCE INTERNATIONAL (2020)

Article Chemistry, Analytical

Blood Concentrations of Designer Benzodiazepines: Relation to Impairment and Findings in Forensic Cases

Gunhild Heide et al.

JOURNAL OF ANALYTICAL TOXICOLOGY (2020)

Article Clinical Neurology

Sleep quality in times of Covid-19 pandemic

Josue Pinto et al.

SLEEP MEDICINE (2020)

Review Substance Abuse

The epidemiology of benzodiazepine misuse: A systematic review

Victoria R. Votaw et al.

DRUG AND ALCOHOL DEPENDENCE (2019)

Article Health Policy & Services

Benzodiazepine Use and Misuse Among Adults in the United States

Donovan T. Maust et al.

PSYCHIATRIC SERVICES (2019)

Article Medical Laboratory Technology

Novel Benzodiazepines (Clonazolam and Flubromazolam) Identified in Candy-Like Pills

Jeffrey D. Pope et al.

JOURNAL OF APPLIED LABORATORY MEDICINE (2018)

Review Anesthesiology

New benzodiazepines for sedation

Elyse M. Cornett et al.

BEST PRACTICE & RESEARCH-CLINICAL ANAESTHESIOLOGY (2018)

Article Biochemical Research Methods

Flubromazolam - Basic pharmacokinetic evaluation of a highly potent designer benzodiazepine

Laura M. Huppertz et al.

DRUG TESTING AND ANALYSIS (2018)

Review Biochemical Research Methods

The emergence of new psychoactive substance (NPS) benzodiazepines: A review

Kieran R. Manchester et al.

DRUG TESTING AND ANALYSIS (2018)

Article Biochemical Research Methods

Detectability of designer benzodiazepines in CEDIA, EMIT II Plus, HEIA, and KIMS II immunochemical screening assays

Madeleine Pettersson Bergstrand et al.

DRUG TESTING AND ANALYSIS (2017)

Review Medicine, General & Internal

Treatment of Benzodiazepine Dependence

Michael Soyka

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Article Medicine, General & Internal

Association between concurrent use of prescription opioids and benzodiazepines and overdose: retrospective analysis

Eric C. Sun et al.

BMJ-BRITISH MEDICAL JOURNAL (2017)

Article Medicine, General & Internal

Association between concurrent use of prescription opioids and benzodiazepines and overdose: retrospective analysis

Eric C. Sun et al.

BMJ-BRITISH MEDICAL JOURNAL (2017)

Article Biochemical Research Methods

In vitro studies on flubromazolam metabolism and detection of its metabolites in authentic forensic samples

Carolina Noble et al.

DRUG TESTING AND ANALYSIS (2017)

Article Toxicology

Flubromazolam - A new life-threatening designer benzodiazepine

Magdalena Lukasik-Glebocka et al.

CLINICAL TOXICOLOGY (2016)

Article Public, Environmental & Occupational Health

Trends in the Concomitant Prescribing of Opioids and Benzodiazepines, 2002-2014

Catherine S. Hwang et al.

AMERICAN JOURNAL OF PREVENTIVE MEDICINE (2016)

Article Public, Environmental & Occupational Health

Increasing Benzodiazepine Prescriptions and Overdose Mortality in the United States, 1996-2013

Marcus A. Bachhuber et al.

AMERICAN JOURNAL OF PUBLIC HEALTH (2016)

Editorial Material Medicine, General & Internal

Flumazenil in benzodiazepine overdose

Howard An et al.

CANADIAN MEDICAL ASSOCIATION JOURNAL (2016)

Article Public, Environmental & Occupational Health

Emergency Department Visits and Overdose Deaths From Combined Use of Opioids and Benzodiazepines

Christopher M. Jones et al.

AMERICAN JOURNAL OF PREVENTIVE MEDICINE (2015)

Letter Psychiatry

Designer benzodiazepines: A new challenge

Bjoern Moosmann et al.

WORLD PSYCHIATRY (2015)

Article Psychiatry

Benzodiazepine Use in the United States

Mark Olfson et al.

JAMA PSYCHIATRY (2015)

Review Substance Abuse

Polydrug abuse: A review of opioid and benzodiazepine combination use

Jermaine D. Jones et al.

DRUG AND ALCOHOL DEPENDENCE (2012)

Article Psychology, Multidisciplinary

Mental Health Literacy Empowering the Community to Take Action for Better Mental Health

Anthony F. Jorm

AMERICAN PSYCHOLOGIST (2012)

Review Neurosciences

Hooked on benzodiazepines: GABAA receptor subtypes and addiction

Kelly R. Tan et al.

TRENDS IN NEUROSCIENCES (2011)

Review Clinical Neurology

Benzodiazepines in epilepsy: pharmacology and pharmacokinetics

J. Riss et al.

ACTA NEUROLOGICA SCANDINAVICA (2008)

Review Infectious Diseases

Praziquantel: mechanisms of action, resistance and new derivatives for schistosomiasis

Michael J. Doenhoff et al.

CURRENT OPINION IN INFECTIOUS DISEASES (2008)

Article Pharmacology & Pharmacy

Fracture risk from psychotropic medications - A population-based analysis

James M. Bolton et al.

JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY (2008)

Article Substance Abuse

Abuse of prescription drugs and the risk of addiction

Wilson A. Compton et al.

DRUG AND ALCOHOL DEPENDENCE (2006)

Review Pharmacology & Pharmacy

Introduction to the special issue on: Benzodiazepine side-effects: From the bench to the clinic

SH Stewart et al.

CURRENT PHARMACEUTICAL DESIGN (2002)