☆ 4.7 Article

Characteristic guaiane sesquiterpenes from Daphne penicillata and ECD/NMR-based assignment of C-1 configuration

ORGANIC CHEMISTRY FRONTIERS (2022)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Plant Sciences

Hexahydroazulene-2(1H)-one Sesquiterpenoids with Bridged Cyclobutane, Oxetane, and Tetrahydrofuran Rings from the Stems of Daphne papyracea with α-Glycosidase Inhibitory Activity

Sheng-Zhuo Huang et al.

Summary: Chemical investigation of Xuehuagou stem extract led to the isolation of new guaiane sesquiterpenoids and known compounds. Some of these compounds showed potential alpha-glycosidase inhibitory activity. The structures and configurations were determined using spectroscopic analysis and X-ray crystallography.

JOURNAL OF NATURAL PRODUCTS (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Polyhydroxylated bergamotane-type sesquiterpenoids from cultures of Paraconiothyrium sporulosum YK-03 and their absolute configurations

Yue-Hu Pei et al.

Summary: Eight undescribed polyhydroxylated bergamotane-type sesquiterpenoids were discovered from a marine mud-associated fungus, and their chemical structures and absolute configurations were successfully determined. Among them, sporuloketals A-B represent two rare tetracyclic compounds. This study also validated the application of ECD empirical rules for determining the absolute configurations of these bergamotane-type sesquiterpenoids for the first time.

PHYTOCHEMISTRY (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Asymmetric Total Synthesis of (-)-Phaeocaulisin A

Aron Peter et al.

Summary: The therapeutic properties of Curcuma have been long known, and recent studies have focused on the biological activities of guaiane-type sesquiterpenes extracted from it. Among these compounds, phaeocaulisin A has shown great potential as an anti-inflammatory and anticancer agent. The researchers have successfully implemented the first enantioselective total synthesis of phaeocaulisin A, which provides a synthetic platform for further studies and drug design.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Guided isolation of daphnane-type diterpenes from Daphne genkwa by molecular network strategies

Si-Hui Mi et al.

Summary: A molecular networking-guided study successfully isolated twelve daphnane-type diterpenoids, including four undescribed compounds, from Daphne genkwa Sieb. et Zucc. The structures of these compounds were determined through spectroscopic analyses, ECD calculations, and single-crystal X-ray diffraction analysis. The isolates demonstrated inhibitory activity against A549 cells, with IC50 values ranging from 7.77 to 20.56 μM, and a preliminary discussion on their structure-activity relationship was conducted. Further experiments revealed that five of these compounds appeared to inhibit A549 cell lines by inducing apoptosis.

PHYTOCHEMISTRY (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Guaiane-type sesquiterpenes from Curcuma wenyujin

Yahui Li et al.

Summary: Eight new sesquiterpenes were isolated from the rhizomes of Curcuma wenyujin. Two of these compounds showed antioxidant activity.

PHYTOCHEMISTRY (2022)

添加到收藏夹

Article Chemistry, Medicinal

Comparison of anti-inflammatory effects of Lonicerae Japonicae Flos and Lonicerae Flos based on network pharmacology

Yu Gao et al.

Summary: Lonicerae Japonicae Flos and Lonicerae Flos exhibit high similarity in treating inflammation, sharing many core targets and biological functions, making them interchangeable in clinical treatment. Organic acids are the main compounds responsible for their anti-inflammatory effects.

CHINESE HERBAL MEDICINES (2021)

添加到收藏夹

Article Chemistry, Medicinal

A strategy for rapid discovery of traceable chemical markers in herbal products using MZmine 2 data processing toolbox: A case of Jing Liqueur

Jing Zhou et al.

Summary: This study developed a strategy to rapidly discover traceable markers in herbal products using HPLC-QTOF-MS and GC-MS, ensuring the consistency of product quality through chemical fingerprint analysis.

CHINESE HERBAL MEDICINES (2021)

添加到收藏夹

Article Chemistry, Organic

Syntheses of the Carotane-type Terpenoids (+)-Schisanwilsonene A and (+)-Tormesol via a Two-Stage Approach

Shu-Bin Mou et al.

Summary: Efficient syntheses of terpenoids with stereo selectivity have been a long-term goal for synthetic chemists. In this study, we described a two-step, enantiospecific synthesis of (+)-schisanwilsonene A and completed the enantiomeric synthesis of (+)-tormesol in five steps. This two-stage strategy offers an economical approach for preparing terpene natural products and their analogues.

ORGANIC LETTERS (2021)

添加到收藏夹

Article Chemistry, Organic

Three Unusual Sesquiterpenes with Distinctive Ring Skeletons from Daphne penicillata Uncovered by Molecular Networking Strategies

Peng Zhao et al.

Summary: Through molecular networking strategies, four unusual sesquiterpenes were isolated from the herb of Daphne penicillata, including Daphnenoids A-C and a biogenetically related Daphnenoid D. Daphnenoid A has a unique caged structure, while Daphnenoids B and C are the first natural sesquiterpenes with spirocyclic systems.

JOURNAL OF ORGANIC CHEMISTRY (2021)

添加到收藏夹

Review Biochemistry & Molecular Biology

Phytochemistry and Pharmacological Activities of the Diterpenoids from the Genus Daphne

Yi-Wen Nie et al.

Summary: Plants of the genus Daphne contain abundant natural diterpenoids with various bioactivities such as anticancer, anti-inflammatory, and anti-HIV effects. Studies have also summarized the structure-activity relationship to facilitate the synthesis and optimization of drugs.

MOLECULES (2021)

添加到收藏夹

Article Chemistry, Organic

Structural Revisions of Two Highly Aromatic Naphthoquinone-Derived Dimers Based on NMR Analysis, Computer-Assisted Structure Elucidation Methods, and Computations

Tian-Ming Lv et al.

Summary: Eleucanainones A and B are two structurally complex naphthoquinone-derived dimers whose original structures were questioned based on preliminary CASE analysis. Structural revisions were proposed using NMR analysis, CASE methods, conformation analysis, and DFT NMR calculations with a custom DP4+ analysis. Additionally, a proposed polyketide-folded biosynthetic pathway for the revised structures.

ORGANIC LETTERS (2021)

添加到收藏夹

Article Chemistry, Organic

Correlations between the ECD spectra and absolute configuration of bridged-ring lactones: revisiting Beecham's rule

Jun-Yao Zhang et al.

Summary: Beecham correlated the sign of the Cotton effect in lactones with the skeleton of bridged lactones, revisited and revised the rule for elucidating their stereochemistry, and provided an alternative way to interpret experimental ECD data for various bridged lactones.

ORGANIC & BIOMOLECULAR CHEMISTRY (2021)

添加到收藏夹

Article Chemistry, Medicinal

Synchronous bond molecular dynamics of conjugated chlorocyclopropyl alk-yn-enes revealed by ECD and UV-vis

Colin K. Skepper et al.

CHIRALITY (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Guaiane type of sesquiterpene with NO inhibitory activity from the root of Wikstroemia indica

Zhihui Liu et al.

BIOORGANIC CHEMISTRY (2020)

添加到收藏夹

Review Chemistry, Medicinal

The genus Daphne: A review of its traditional uses, phytochemistry and pharmacology

Giorgi Moshiashvili et al.

FITOTERAPIA (2020)

添加到收藏夹

Article Chemistry, Physical

An sp-hybridized all-carboatomic ring, cyclo[18]carbon: Bonding character, electron delocalization, and aromaticity

Zeyu Liu et al.

CARBON (2020)

添加到收藏夹

Article Chemistry, Physical

Highly efficient luminescence from space-confined charge-transfer emitters

Xun Tang et al.

NATURE MATERIALS (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Sesquiterpenoids from the roots of Daphne genkwa Siebold et Zucc. With potential anti-inflammatory activity

Rui Guo et al.

PHYTOCHEMISTRY (2020)

添加到收藏夹

Article Chemistry, Medicinal

Chamaejasmins, cytotoxic guaiane sesquiterpenes from the root of Stellera chamaejasme L.

Ahmed H. H. El-Desoky et al.

FITOTERAPIA (2020)

添加到收藏夹

Review Biochemistry & Molecular Biology

Natural disesquiterpenoids: an update

Lie-Feng Ma et al.

NATURAL PRODUCT REPORTS (2020)

添加到收藏夹

Article Chemistry, Applied

A new guaiane sesquiterpene from cultures of the fungus Fulvifomes kanehirae

Jian-Hai Ding et al.

NATURAL PRODUCT RESEARCH (2019)

添加到收藏夹

Article Plant Sciences

Guaiane-Type Sesquiterpenoids from the Roots of Daphne genkwa and Evaluation of Their Neuroprotective Effects

Qiang Ren et al.

JOURNAL OF NATURAL PRODUCTS (2019)

添加到收藏夹

Article Chemistry, Organic

Scope of the 2(5H)-furanone helicity rule: a combined ECD, VCD, and DFT investigation

Fernando M. dos Santos et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2018)

添加到收藏夹

Article Chemistry, Organic

Schinortriterpenoids with Identical Configuration but Distinct ECD Spectra Generated by Nondegenerate Exciton Coupling

Yi-Ming Shi et al.

ORGANIC LETTERS (2018)

添加到收藏夹

Article Chemistry, Medicinal

Autophagy antagonizes apoptosis induced by flavan enantiomers from Daphne giraldii in hepatic carcinoma cells in vitro

Qian Sun et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)

添加到收藏夹

Article Plant Sciences

Revisiting the Chemistry of Guaiacwood Oil: Identification and Formation Pathways of 5,11-and 10,11-Epoxyguaianes

Loic Tissandie et al.

JOURNAL OF NATURAL PRODUCTS (2017)

添加到收藏夹

Article Materials Science, Multidisciplinary

Theoretical insights on the electroluminescent mechanism of thermally activated delayed fluorescence emitters

Lili Lin et al.

ORGANIC ELECTRONICS (2017)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking

Mingxun Wang et al.

NATURE BIOTECHNOLOGY (2016)

添加到收藏夹

Article Plant Sciences

Guaiane-Type Sesquiterpenes from Curcuma phaeocaulis and Their Inhibitory Effects on Nitric Oxide Production

Yue Liu et al.

JOURNAL OF NATURAL PRODUCTS (2013)

添加到收藏夹

Review Biochemistry & Molecular Biology

Natural sesquiterpenoids

Braulio M. Fraga

NATURAL PRODUCT REPORTS (2013)

添加到收藏夹

Article Chemistry, Multidisciplinary

Multiwfn: A multifunctional wavefunction analyzer

Tian Lu et al.

JOURNAL OF COMPUTATIONAL CHEMISTRY (2012)

添加到收藏夹

Article Plant Sciences

Guaiane Sesquiterpenes from Biscogniauxia nummularia Featuring Potent Antigerminative Activity

Severine Amand et al.

JOURNAL OF NATURAL PRODUCTS (2012)

添加到收藏夹

Article Plant Sciences

Sesquiterpenes from Blumea balsamifera

Osamu Shirota et al.

JOURNAL OF NATURAL PRODUCTS (2011)

添加到收藏夹

Article Chemistry, Multidisciplinary

A Brief Synthesis of (-)-Englerin A

Zhenwu Li et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)

添加到收藏夹

Article Chemistry, Multidisciplinary

Enantioselective Synthesis of (-)-Englerins A and B

Kian Molawi et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2010)

添加到收藏夹

Article Chemistry, Multidisciplinary

Total Synthesis of Englerin A

K. C. Nicolaou et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)

添加到收藏夹

Article Chemistry, Organic

Enantioselective Formal Synthesis of (-)-Englerin A via a Rh-Catalyzed [4+3] Cycloaddition Reaction

Jing Xu et al.

ORGANIC LETTERS (2010)

添加到收藏夹

Article Chemistry, Multidisciplinary

Total Synthesis and Absolute Configuration of the Guaiane Sesquiterpene Englerin A

Matthieu Willot et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2009)

添加到收藏夹

Article Chemistry, Organic

Englerin A, a Selective Inhibitor of Renal Cancer Cell Growth, from Phyllanthus engleri

Ranjala Ratnayake et al.

ORGANIC LETTERS (2009)

添加到收藏夹

Article Chemistry, Medicinal

Aromatic constituents from the heartwood of Santalum album L.

TH Kim et al.

CHEMICAL & PHARMACEUTICAL BULLETIN (2005)

添加到收藏夹

Article Chemistry, Medicinal

Chiroptical properties of 2,3-dihydrobenzo[b]furan and chromane chromophores in naturally occurring O-heterocycles

S Antus et al.

CHIRALITY (2001)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.