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Nuclear lamins are not required for lamina-associated domain organization in mouse embryonic stem cells
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J. Scharner et al.
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Takamasa Harada et al.
JOURNAL OF CELL BIOLOGY (2014)
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Vitaly Kochin et al.
JOURNAL OF CELL SCIENCE (2014)
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Daniel Z. Bar et al.
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Chemical Inhibition of NAT10 Corrects Defects of Laminopathic Cells
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Nuclear Envelope Lamin-A Couples Actin Dynamics with Immunological Synapse Architecture and T Cell Activation
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PLOS GENETICS (2014)
Induced Pluripotent Stem Cells Reveal Functional Differences Between Drugs Currently Investigated in Patients With Hutchinson-Gilford Progeria Syndrome
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STEM CELLS TRANSLATIONAL MEDICINE (2014)
Genome-wide analysis links emerin to neuromuscular junction activity in Caenorhabditis elegans
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CELL (2013)
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CELL (2013)
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CELL (2013)
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CELL (2013)
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CELL (2013)
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GENOME RESEARCH (2013)
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GENOME RESEARCH (2013)
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Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force
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JOURNAL OF CELL BIOLOGY (2013)
Identification of mitochondrial dysfunction in Hutchinson-Gilford progeria syndrome through use of stable isotope labeling with amino acids in cell culture
Jose Rivera-Torres et al.
JOURNAL OF PROTEOMICS (2013)
Targeting Isoprenylcysteine Methylation Ameliorates Disease in a Mouse Model of Progeria
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Joe Swift et al.
SCIENCE (2013)
Specific nuclear envelope transmembrane proteins can promote the location of chromosomes to and from the nuclear periphery
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Lamin A Δexon9 mutation leads to telomere and chromatin defects but not genomic instability
Arindam Das et al.
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CELL (2012)
Step-Wise Methylation of Histone H3K9 Positions Heterochromatin at the Nuclear Periphery
Benjamin D. Towbin et al.
CELL (2012)
Resveratrol Rescues SIRT1-Dependent Adult Stem Cell Decline and Alleviates Progeroid Features in Laminopathy-Based Progeria
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CELL METABOLISM (2012)
Nuclear damages and oxidative stress: new perspectives for laminopathies
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EUROPEAN JOURNAL OF HISTOCHEMISTRY (2012)
Lamin B Receptor Recognizes Specific Modifications of Histone H4 in Heterochromatin Formation
Yasuhiro Hirano et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Sp1 Transcription Factor Interaction with Accumulated Prelamin A Impairs Adipose Lineage Differentiation in Human Mesenchymal Stem Cells: Essential Role of Sp1 in the Integrity of Lipid Vesicles
Garbine Ruiz de Eguino et al.
STEM CELLS TRANSLATIONAL MEDICINE (2012)
Transient nuclear envelope rupturing during interphase in human cancer cells
Jesse D. Vargas et al.
NUCLEUS (2012)
Conserved cysteine residues in the mammalian lamin A tail are essential for cellular responses to ROS generation
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AGING CELL (2011)
A new pathway that regulates 53BP1 stability implicates Cathepsin L and vitamin D in DNA repair
Ignacio Gonzalez-Suarez et al.
EMBO JOURNAL (2011)
Autophagic degradation of farnesylated prelamin A as a therapeutic approach to lamin-linked progeria
V. Cenni et al.
EUROPEAN JOURNAL OF HISTOCHEMISTRY (2011)
The accumulation of un-repairable DNA damage in laminopathy progeria fibroblasts is caused by ROS generation and is prevented by treatment with N-acetyl cysteine
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HUMAN MOLECULAR GENETICS (2011)
Progerin and telomere dysfunction collaborate to trigger cellular senescence in normal human fibroblasts
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JOURNAL OF CLINICAL INVESTIGATION (2011)
Rapamycin Reverses Cellular Phenotypes and Enhances Mutant Protein Clearance in Hutchinson-Gilford Progeria Syndrome Cells
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SCIENCE TRANSLATIONAL MEDICINE (2011)
Prelamin A Acts to Accelerate Smooth Muscle Cell Senescence and Is a Novel Biomarker of Human Vascular Aging
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CIRCULATION (2010)
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MOLECULAR BIOLOGY OF THE CELL (2008)
A novel role for the nuclear membrane protein emerin in association of the centrosome to the outer nuclear membrane
Georgia Salpingidou et al.
JOURNAL OF CELL BIOLOGY (2007)
Matrix elasticity directs stem cell lineage specification
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CELL (2006)