Standard Operating Procedures for Biospecimen Collection, Processing, and Storage From the Type 1 Diabetes in Acute Pancreatitis Consortium

Article Endocrinology & Metabolism

Characterising the age-dependent effects of risk factors on type 1 diabetes progression

Michelle So et al.

Summary: Analyzing the age-varying effect of disease predictors improves understanding and prediction of type 1 diabetes disease progression, and should be leveraged to refine prediction models and guide mechanistic studies.

DIABETOLOGIA (2022)

添加到收藏夹

Article Medicine, Research & Experimental

Biorepository best practices for research and clinical investigations

Micheline Sanderson-November et al.

Summary: Translational research relies on high-quality specimens and clinical annotations for accurate and verifiable results. In a multi-site clinical research network, strict standardization of operational workflows and procedures is needed to ensure specimen quality and consistency. The practices of a central biorepository can inform best practices for specimen integrity in multi-site clinical research.

CONTEMPORARY CLINICAL TRIALS (2022)

添加到收藏夹

Article Gastroenterology & Hepatology

Evaluating the Immunopathogenesis of Diabetes After Acute Pancreatitis in the Diabetes RElated to Acute Pancreatitis and Its Mechanisms Study From the Type 1 Diabetes in Acute Pancreatitis Consortium

Anna Casu et al.

Summary: The association between acute pancreatitis (AP) and diabetes mellitus (DM) is well-established, but the immune mechanisms involved have not been well-defined. The DREAM study aims to understand the frequency and phenotype of DM developing after AP, as well as the immunologic mechanisms and their impact on DM development.

PANCREAS (2022)

添加到收藏夹

Article Gastroenterology & Hepatology

Assessing the Pathophysiology of Hyperglycemia in the Diabetes RElated to Acute Pancreatitis and Its Mechanisms Study From the Type 1 Diabetes in Acute Pancreatitis Consortium

Kathleen M. Dungan et al.

Summary: This article describes the objectives, hypotheses, and methods of the DREAM study, which aims to comprehensively assess the metabolic and endocrine changes that precede and follow the development of diabetes mellitus after acute pancreatitis.

PANCREAS (2022)

添加到收藏夹

Article Gastroenterology & Hepatology

Rationale and Development of a Data Coordinating Center to Support the Type 1 Diabetes in Acute Pancreatitis Consortium

Anne-Marie Dyer et al.

Summary: The T1DAPC DCC supports the consortium through its expertise in various areas and its matrix management system has been highly effective in managing all responsibilities.

PANCREAS (2022)

添加到收藏夹

Article Gastroenterology & Hepatology

Rationale and Design for the Diabetes RElated to Acute Pancreatitis and Its Mechanisms Study A Prospective Cohort Study From the Type 1 Diabetes in Acute Pancreatitis Consortium

Phil A. Hart et al.

Summary: Diabetes mellitus after acute pancreatitis is increasingly recognized as an important late and chronic complication. The DREAM study aims to address the challenges in determining the incidence rate and understanding the underlying mechanisms of diabetes after acute pancreatitis. This article summarizes the literature on the epidemiology of diabetes after acute pancreatitis and provides an overview of the DREAM study.

PANCREAS (2022)

添加到收藏夹

Article Endocrinology & Metabolism