Mille-feuille paper: a novel type of filter architecture for advanced virus separation applications

Mille-feuille (a thousand leaves) paper is the first non-woven, wet-laid filter paper, composed of 100% native cellulose, which is capable of removal of the worst-case model virus, the non-enveloped parvoviruses, i. e. minute virus of mice (MVM; 18-20 nm), from water with a log10 reduction value (LRV) >5 (>99.999%). We further illustrate how the flow rate across the mille-feuille paper can be increased exponentially so that flux rates in the order of 350 L m(-2) h(-1) bar(-1) can be potentially achieved.