☆ 4.6 Review

Central sensitization: clinical utility of a physiological concept for the International Statistical Classification of Diseases and Related Health Problems and for nociplastic pain

PAIN (2022)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Anesthesiology

Conditioned pain modulation is more efficient in patients with painful diabetic polyneuropathy than those with nonpainful diabetic polyneuropathy

Yelena Granovsky et al.

Summary: According to the study, patients with painful diabetic polyneuropathy (DPN) have lower efficiency in conditioned pain modulation (CPM) compared to those with nonpainful DPN. However, these patients demonstrate unexpectedly higher efficiency in thermal CPM. Higher efficiency in thermal CPM is associated with higher levels of clinical pain and greater loss of mechanical sensation. Patients with mechanical hypoesthesia also show higher efficiency in thermal CPM.

PAIN (2022)

添加到收藏夹

Letter Anesthesiology

Proposed clinical criteria for nociplastic pain in the musculoskeletal system are flawed

Milton L. Cohen

PAIN (2022)

添加到收藏夹

Article Anesthesiology

No pain, still gain (of function): the relation between sensory profiles and the presence or absence of self-reported pain in a large multicenter cohort of patients with neuropathy

Julia Forstenpointner et al.

Summary: The study revealed that hypersensitivity symptoms, including hyperalgesia and allodynia, are present in patients with central and peripheral lesions of the somatosensory system, even if they do not report spontaneous pain. There was a difference in pain sensitivity between painful and painless neuropathic conditions, with hyperalgesia more common in painful mononeuropathy and hypoalgesia more pronounced in painful polyneuropathy.

PAIN (2021)

添加到收藏夹

Article Anesthesiology

The serotonin receptor 2A (HTR2A) rs6313 variant is associated with higher ongoing pain and signs of central sensitization in neuropathic pain patients

Juliane Sachau et al.

Summary: The study revealed an association of the HTR2A gene variant rs6313 with pinprick hyperalgesia and increased levels of ongoing pain in neuropathic pain patients with sensory loss. This suggests that the HTR2A receptor may play a crucial role in the development of central sensitization in neuropathic pain.

EUROPEAN JOURNAL OF PAIN (2021)

添加到收藏夹

Article Anesthesiology

Sensory and pain modulation profiles of ongoing central neuropathic extremity pain in multiple sclerosis

Iva Srotova et al.

Summary: This study found a higher prevalence of the 'sensory loss' prototypic sensory phenotype in multiple sclerosis patients with central neuropathic extremity pain, compared to pain-free patients. The higher degree of disability underscored the possible role of higher lesion load in the somatosensory pathways in this particular 'deafferentation' type of central neuropathic pain.

EUROPEAN JOURNAL OF PAIN (2021)

添加到收藏夹

Article Anesthesiology

Classification algorithm for the International Classification of Diseases-11 chronic pain classification: development and results from a preliminary pilot evaluation

Beatrice Korwisi et al.

Summary: The ICD-11 chronic pain classification consists of about 100 diagnoses with specific diagnostic criteria, and the CAL-CP aims to guide users through these criteria with a decision tree. Initial pilot evaluation shows good clinical utility of the algorithm in structuring a reliable way to diagnose chronic pain. Further studies are needed to evaluate its utility and impact on diagnosis accuracy.

PAIN (2021)

添加到收藏夹

Review Neurosciences

NMDA receptors and synaptic plasticity in the anterior cingulate cortex

Qi-Yu Chen et al.

Summary: The anterior cingulate cortex plays a critical role in pain modulation and pain-related emotional disorders. Long-term potentiation and long-term depression are key mechanisms underlying chronic pain and emotional disorders, with NMDARs playing important roles in these processes. Inhibiting NMDAR subtypes may offer potential drug targets for these conditions.

NEUROPHARMACOLOGY (2021)

添加到收藏夹

Article Clinical Neurology

The N13 spinal component of somatosensory evoked potentials is modulated by heterotopic noxious conditioning stimulation suggesting an involvement of spinal wide dynamic range neurons

Giuseppe Di Pietro et al.

Summary: This study in healthy humans demonstrated that a heterotopic noxious conditioning stimulus significantly reduced the amplitude of the N13 SEP, suggesting that the N13 SEP may be generated by the segmental postsynaptic response of dorsal horn wide dynamic range neurons.

NEUROPHYSIOLOGIE CLINIQUE-CLINICAL NEUROPHYSIOLOGY (2021)

添加到收藏夹

Article Neurosciences

Spinal cord fractalkine (CX3CL1) signaling is critical for neuronal sensitization in experimental nonspecific, myofascial low back pain

Katharina Sessler et al.

Summary: Fractalkine signaling plays a critical role in the sensitization of dorsal horn neurons induced by repetitive nociceptive stimuli, suggesting it may be a potential target for preventing nonspecific, myofascial low back pain. Blocking fractalkine signaling with neutralizing antibodies prevents spinal sensitization, while intrathecal administration of fractalkine induces similar sensitization patterns as nociceptive stimuli.

JOURNAL OF NEUROPHYSIOLOGY (2021)

添加到收藏夹

Review Cell Biology

Brain circuits for pain and its treatment

Nicole Mercer Lindsay et al.

Summary: Pain is a multidimensional experience and pain aversiveness is a major contributor to patient suffering in chronic pain. Various interventions, such as pharmacological, stimulation, neurofeedback, surgical, and cognitive-behavioral approaches, are used to modulate neural activity in the brain circuits related to pain perception for chronic pain relief.

SCIENCE TRANSLATIONAL MEDICINE (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Modulation of the N13 component of the somatosensory evoked potentials in an experimental model of central sensitization in humans

A. Di Lionardo et al.

Summary: This neurophysiological study demonstrated that capsaicin-induced central sensitization modulated N13 SEP amplitude, which was prevented by pregabalin, suggesting N13 SEP as a potential biomarker for changes in dorsal horn excitability during central sensitization.

SCIENTIFIC REPORTS (2021)

添加到收藏夹

Review Anesthesiology

Human surrogate models of central sensitization: A critical review and practical guide

Charles Quesada et al.

Summary: The study conducted a systematic review and meta-analysis of human pain models, identifying five reliable models that induce secondary hyperalgesia and have pharmacological profiles similar to clinical conditions. These models can inform basic research for new drug development by providing helpful potential biomarkers.

EUROPEAN JOURNAL OF PAIN (2021)

添加到收藏夹

Review Anesthesiology

Chronic nociplastic pain affecting the musculoskeletal system: clinical criteria and grading system

Eva Kosek et al.

PAIN (2021)

添加到收藏夹

Article Medicine, General & Internal

Expert consensus on the diagnosis and treatment of myofascial pain syndrome

Qi-Wang Cao et al.

Summary: Myofascial pain syndrome (MPS) lacks unified diagnostic criteria and treatment standards, the Chinese Pain Specialist Consensus is important for standardizing the diagnosis and treatment of MPS.

WORLD JOURNAL OF CLINICAL CASES (2021)

添加到收藏夹

Review Medicine, General & Internal

Nociplastic Pain Criteria or Recognition of Central Sensitization? Pain Phenotyping in the Past, Present and Future

Jo Nijs et al.

Summary: IASP has recently released new clinical criteria for nociplastic pain affecting the musculoskeletal system, aiming to help clinicians identify and classify patients with chronic pain more accurately. These new criteria are more comprehensive and robust, representing important steps towards precision pain medicine, although further studies are needed to validate their clinimetric and psychometric properties.

JOURNAL OF CLINICAL MEDICINE (2021)

添加到收藏夹

Article Neurosciences

Rat dorsal horn neurons primed by stress develop a long-lasting manifest sensitization after a short-lasting nociceptive low back input

Sathish Kumar Singaravelu et al.

Summary: The study showed that repeated restraint stress followed by a short-lasting nociceptive input can lead to manifest sensitization of dorsal horn neurons to deep input, particularly from tissue outside the low back, along with an increased resting activity.

PAIN REPORTS (2021)

添加到收藏夹

Article Neurosciences

Spinal Mobilization Prevents NGF-Induced Trunk Mechanical Hyperalgesia and Attenuates Expression of CGRP

William R. Reed et al.

FRONTIERS IN NEUROSCIENCE (2020)

添加到收藏夹

Article Orthopedics

Central Sensitization in Musculoskeletal Pain: Lost in Translation?

Hubert van Griensven et al.

JOURNAL OF ORTHOPAEDIC & SPORTS PHYSICAL THERAPY (2020)

添加到收藏夹

Review Anesthesiology

Chronic pain as a symptom or a disease: the IASP Classification of Chronic Pain for the International Classification of Diseases (ICD-11)

Rolf-Detlef Treede et al.

PAIN (2019)

添加到收藏夹

Review Anesthesiology

The IASP classification of chronic pain for ICD-11: chronic primary pain

Michael Nicholas et al.

PAIN (2019)

添加到收藏夹

Review Anesthesiology

Neuroinflammation and Central Sensitization in Chronic and Widespread Pain

Ru-Rong Ji et al.

ANESTHESIOLOGY (2018)

添加到收藏夹

Article Anesthesiology

Short-term swimming exercise attenuates the sensitization of dorsal horn neurons in rats with NGF-induced low back pain

G. de Azambuja et al.

EUROPEAN JOURNAL OF PAIN (2018)

添加到收藏夹

Article Anesthesiology

Pathophysiological mechanisms of neuropathic pain: comparison of sensory phenotypes in patients and human surrogate pain models

Jan Vollert et al.

PAIN (2018)

添加到收藏夹

Article Clinical Neurology

Spinal cord stimulation modulates descending pain inhibition and temporal summation of pricking pain in patients with neuropathic pain

Sigrid Schuh-Hofer et al.

ACTA NEUROCHIRURGICA (2018)

添加到收藏夹

Article Neurosciences

Prevention and reversal of latent sensitization of dorsal horn neurons by glial blockers in a model of low back pain in male rats

Juanjuan Zhang et al.

JOURNAL OF NEUROPHYSIOLOGY (2017)

添加到收藏夹

Article Anesthesiology

Peripheral neuropathic pain: a mechanism-related organizing principle based on sensory profiles

Ralf Baron et al.

PAIN (2017)

添加到收藏夹

Article Anesthesiology

Stratifying patients with peripheral neuropathic pain based on sensory profiles: algorithm and sample size recommendations

Jan Vollert et al.

PAIN (2017)

添加到收藏夹

Article Anesthesiology

Conditioned pain modulation in patients with nonspecific chronic back pain with chronic local pain, chronic widespread pain, and fibromyalgia

Andreas Gerhardt et al.

PAIN (2017)

添加到收藏夹

Review Orthopedics

Central sensitization in chronic low back pain: A narrative review

Ilaria Sanzarello et al.

JOURNAL OF BACK AND MUSCULOSKELETAL REHABILITATION (2016)

添加到收藏夹

Review Neurosciences

Synaptic plasticity in the anterior cingulate cortex in acute and chronic pain

Tim V. P. Bliss et al.

NATURE REVIEWS NEUROSCIENCE (2016)

添加到收藏夹

Review Neurosciences

CONTRIBUTION OF SYNAPTIC PLASTICITY IN THE INSULAR CORTEX TO CHRONIC PAIN

Min Zhuo

NEUROSCIENCE (2016)

添加到收藏夹

Review Anesthesiology

Do we need a third mechanistic descriptor for chronic pain states?

Eva Kosek et al.

PAIN (2016)

添加到收藏夹

Article Multidisciplinary Sciences

Gliogenic LTP spreads widely in nociceptive pathways

M. T. Kronschlaeger et al.

SCIENCE (2016)

添加到收藏夹

Article Clinical Neurology

Capsaicin-sensitive C- and A-fibre nociceptors control long-term potentiation-like pain amplification in humans

Florian Henrich et al.

BRAIN (2015)

添加到收藏夹

Article Medicine, General & Internal

Neuropathic Pain: Principles of Diagnosis and Treatment

Ian Gilron et al.

MAYO CLINIC PROCEEDINGS (2015)

添加到收藏夹

Article Anesthesiology

Induction of long-term potentiation and long-term depression is cell-type specific in the spinal cord

Hee Young Kim et al.

PAIN (2015)

添加到收藏夹

Review Anesthesiology

A classification of chronic pain for ICD-11

Rolf-Detlef Treede et al.

PAIN (2015)

添加到收藏夹

Article Anesthesiology

Recommendations on practice of conditioned pain modulation (CPM) testing

D. Yarnitsky et al.

EUROPEAN JOURNAL OF PAIN (2015)

添加到收藏夹

Review Neurosciences

Placebo Analgesia: A Predictive Coding Perspective

Christian Buechel et al.

NEURON (2014)

添加到收藏夹

Article Neurosciences

Pinprick-evoked brain potentials: a novel tool to assess central sensitization of nociceptive pathways in humans

G. D. Iannetti et al.

JOURNAL OF NEUROPHYSIOLOGY (2013)

添加到收藏夹

Article Anesthesiology

Repeated intramuscular injections of nerve growth factor induced progressive muscle hyperalgesia, facilitated temporal summation, and expanded pain areas

Koei Hayashi et al.

PAIN (2013)

添加到收藏夹

Article Anesthesiology

Injection of nerve growth factor into a low back muscle induces long-lasting latent hypersensitivity in rat dorsal horn neurons

Ulrich Hoheisel et al.

PAIN (2013)

添加到收藏夹

Article Anesthesiology

NGF-evoked sensitization of muscle fascia nociceptors in humans

Saskia Deising et al.

PAIN (2012)

添加到收藏夹

Article Anesthesiology

Conditioned pain modulation predicts duloxetine efficacy in painful diabetic neuropathy

David Yarnitsky et al.

PAIN (2012)

添加到收藏夹

Review Neurosciences

Long-term potentiation in spinal nociceptive pathways as a novel target for pain therapy

Ruth Ruscheweyh et al.

MOLECULAR PAIN (2011)

添加到收藏夹

Article Anesthesiology

Analysis of hyperalgesia time courses in humans after painful electrical high-frequency stimulation identifies a possible transition from early to late LTP-like pain plasticity

Doreen B. Pfau et al.

PAIN (2011)

添加到收藏夹

Article Rehabilitation

Clinical indicators of 'nociceptive', 'peripheral neuropathic' and 'central' mechanisms of musculoskeletal pain. A Delphi survey of expert clinicians

Keith M. Smart et al.

MANUAL THERAPY (2010)

添加到收藏夹

Article Clinical Neurology

Pregabalin for painful HIV neuropathy A randomized, double-blind, placebo-controlled trial

D. M. Simpson et al.

NEUROLOGY (2010)

添加到收藏夹

Article Clinical Neurology

Differential endogenous pain modulation in complex-regional pain syndrome

Frank Seifert et al.

BRAIN (2009)

添加到收藏夹

Review Neurosciences

Descending control of nociception: Specificity, recruitment and plasticity

M. M. Heinricher et al.

BRAIN RESEARCH REVIEWS (2009)

添加到收藏夹

Article Neurosciences

Involuntary Orienting of Attention to Nociceptive Events: Neural and Behavioral Signatures

Valery Legrain et al.

JOURNAL OF NEUROPHYSIOLOGY (2009)

添加到收藏夹

Review Clinical Neurology

Central Sensitization: A Generator of Pain Hypersensitivity by Central Neural Plasticity

Alban Latremoliere et al.

JOURNAL OF PAIN (2009)

添加到收藏夹

Review Physiology

Models and Mechanisms of Hyperalgesia and Allodynia

Juergen Sandkuehler

PHYSIOLOGICAL REVIEWS (2009)

添加到收藏夹

Article Multidisciplinary Sciences

Direct Evidence for Spinal Cord Involvement in Placebo Analgesia

Falk Eippert et al.

SCIENCE (2009)

添加到收藏夹

Review Anesthesiology

The Kyoto protocol of IASP Basic Pain Terminology

John D. Loeser et al.

PAIN (2008)

添加到收藏夹

Review Clinical Neurology

Neuropathic pain - Redefinition and a grading system for clinical and research purposes

R. -D. Treede et al.

NEUROLOGY (2008)

添加到收藏夹

Article Anesthesiology

Modality-specific sensory changes in humans after the induction of long-term potentiation (LTP) in cutaneous nociceptive pathways

Stefanie Lang et al.

PAIN (2007)

添加到收藏夹

Review Rheumatology

Regional pain syndrome: clinical characteristics, mechanisms and management

Geoffrey Littlejohn

NATURE CLINICAL PRACTICE RHEUMATOLOGY (2007)

添加到收藏夹

Article Neurosciences

Local and descending circuits regulate long-term potentiation and zif268 expression in spinal neurons

Lars Jorgen Rygh et al.

EUROPEAN JOURNAL OF NEUROSCIENCE (2006)

添加到收藏夹

Article Multidisciplinary Sciences

Synaptic amplifier of inflammatory pain in the spinal dorsal horn

Hiroshi Ikeda et al.

SCIENCE (2006)

添加到收藏夹

Review Anesthesiology

Core outcome measures for chronic pain clinical trials: IMMPACT recommendations

RH Dworkin et al.

PAIN (2005)

添加到收藏夹

Article Neurosciences

Perceptual correlates of nociceptive long-term potentiation and long-term depression in humans

T Klein et al.

JOURNAL OF NEUROSCIENCE (2004)

添加到收藏夹

Article Anesthesiology

Preoperative prediction of severe postoperative pain

CJ Kalkman et al.

PAIN (2003)

添加到收藏夹

Article Neurosciences

Response properties and organization of nociceptive neurons in area 1 of monkey primary somatosensory cortex

DR Kenshalo et al.

JOURNAL OF NEUROPHYSIOLOGY (2000)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.