期刊
出版社
IEEE
DOI: 10.1109/MetroInd4.0IoT54413.2022.9831695
关键词
IDE capacitive sensor; Phenylalanine; Ammonia; Inkjet printing; YSZ
类别
资金
- Action 1.1.5 POR FESR 2014-2020 [CUP G89J18000710007]
This paper presents the development of a low-cost biosensor for the timely detection of phenylalanine levels in patients with Phenylketonuria. The sensor utilizes an indirect measurement method by detecting the concentration of ammonia produced from an enzymatic reaction. Capacitive sensing is adopted to detect ammonia, based on its influence on the dielectric permittivity of an yttria-stabilized zirconium oxide layer. An UV/ozone treatment is applied to improve the sensor efficiency.
This paper deals with the development of a low-cost biosensor for the timely detection of phenylalanine levels in patients affected by Phenylketonuria. The proposed approach exploits an indirect measurement of phenylalanine by detecting the concentration of Ammonia resulting from an enzymatic reaction of the analyte. A capacitive sensing approach for the detection of Ammonia is adopted, which is based on the influence of Ammonia on the dielectric permittivity of an Yttria-stabilized Zirconium Oxide layer, deposited over an inkjet printed capacitor with an interdigitated electrodes geometry. An UV/ozone treatment of the sensitive oxide layer is performed with the aim of improving the sensor efficiency. The experimental results of measurement surveys performed on both non-treated and UV/ozone treated device samples are reported here.
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