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SARS-CoV-2 Cross-Reactivity in Prepandemic Serum from Rural Malaria-Infected Persons, Cambodia

EMERGING INFECTIOUS DISEASES (2022)

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Article Immunology

SARS-CoV-2 Cross-Reactivity in Prepandemic Serum from Rural Malaria- Infected Persons, Cambodia

Jessica Manning et al.

Summary: Inhabitants of the Greater Mekong Subregion in Cambodia have been exposed to pathogens that may affect serologic cross-reactivity with severe acute respiratory syndrome coronavirus 2. A prepandemic serosurvey of 528 malaria-infected individuals demonstrated higher-than-expected positivity of nonneutralizing IgG to spike and receptor-binding domain antigens. These findings could impact the interpretation of large-scale serosurveys.

EMERGING INFECTIOUS DISEASES (2022)

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Dynamics of SARS-CoV-2 neutralising antibody responses and duration of immunity: a longitudinal study

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Summary: The study investigated the dynamics of neutralising antibody response in patients who have recovered from COVID-19, finding great variations and suggesting that predicting immune longevity can only be accurately determined at the individual level. The findings emphasize the importance of public health and social measures in the ongoing pandemic outbreak response, and may have implications for the longevity of immunity after vaccination.

LANCET MICROBE (2021)

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Article Biology

Impact of asymptomatic Plasmodium falciparum infection on the risk of subsequent symptomatic malaria in a longitudinal cohort in Kenya

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Summary: This study in sub-Saharan Africa found that asymptomatic Plasmodium falciparum infections can quickly lead to symptomatic malaria, with females at higher risk than males. The increased risk of symptomatic malaria was observed in asymptomatic infections of all densities and in people of all ages, with long-term risk present in children under age 5. In high-transmission settings, targeting asymptomatic P. falciparum infections may help reduce the incidence of symptomatic illness.

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Chee Wah Tan et al.

NATURE BIOTECHNOLOGY (2020)

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Neutralizing Antibodies Correlate with Protection from SARS-CoV-2 in Humans during a Fishery Vessel Outbreak with a High Attack Rate

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JOURNAL OF CLINICAL MICROBIOLOGY (2020)

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