Radical directed regioselective functionalization of diverse alkene derivatives

Regioselective vicinal difunctionalization of diverse alkene derivatives was successfully carried out using readily available carboxylic acids. Molecular oxygen in the atmospheric air tethered with the substrate to form the corresponding peroxygenated products in good yields. All the reactions were carried out at room temperature itself. Apart from the synthesis of peroxygenated products, hydroacylated products were obtained by utilizing Csp(2) hybridized carbonyl radicals instead of Csp(3) hybridized alkyl radicals.

Automated summary

Regioselective vicinal difunctionalization of diverse alkene derivatives was successfully achieved using easily accessible carboxylic acids. The reaction involved molecular oxygen in the air, resulting in the formation of peroxygenated products in good yields. The reactions were conducted at room temperature, and hydroacylated products were obtained by utilizing Csp(2) hybridized carbonyl radicals.