4.3 Article

Irrational ophthalmic fixed-dose combinations for dry eye syndrome

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INDIAN JOURNAL OF OPHTHALMOLOGY
卷 70, 期 10, 页码 3687-3689

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WOLTERS KLUWER MEDKNOW PUBLICATIONS
DOI: 10.4103/ijo.IJO_1169_22

关键词

Fixed-dose combinations; FDCs; Drug Technical Advisory Board [DTAB]; Dry eye; eyedrops; irrational ophthalmic drops

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This paper discusses the ingredients of some Fixed Dose Combinations (FDCs) marketed for Dry Eye Syndrome (DES), emphasizing the need for careful evaluation of their ingredients and efficacy and safety data, and prescribing them only if necessary.
Dry eye syndrome (DES) is a common disorder with rising incidence due to increased use of digital devices. While multiple treatment options are available, some are not efficacious or sometimes even safe for use in DES. This is particularly true for Fixed Dose Combinations (FDCs) that may contain ingredients having no rational for their use or may actually be harmful. Various committees appointed by the Government have reviewed several FDCs marketed in India and found some of them to be irrational and recommended for their removal. This paper discusses the contents of some of these FDCs marketed for DES with an aim to ensure that prescribers are mindful of their ingredients and whether there is adequate data about their efficacy and safety and prescribe them only if they consider them necessary for managing the patient.

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