期刊
CHEMICAL SOCIETY REVIEWS
卷 51, 期 22, 页码 9203-9242出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/d2cs00359g
关键词
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资金
- National Natural Science Foundation of China [62103050]
- Natural Sciences and Engineering Research Council of Canada [LLRP 548593-19, CREATE 482073-16, RGPIN 2019-04867, RTI2019-00300]
- University of Toronto's Medicine by Design initiative
- Canada First Research Excellence Fund
The rapid development of micromanipulation technologies has provided new opportunities for the actuation and assembly of nano/micro-objects. Optoelectronic tweezers (OET) is a state-of-the-art technique that combines light stimuli with electric field to control micro-objects. OET offers tremendous advantages in micromanipulation, such as programmability, flexibility, versatility, and high-throughput.
The rapid development of micromanipulation technologies has opened exciting new opportunities for the actuation, selection and assembly of a variety of non-biological and biological nano/micro-objects for applications ranging from microfabrication, cell analysis, tissue engineering, biochemical sensing, to nano/micro-machines. To date, a variety of precise, flexible and high-throughput manipulation techniques have been developed based on different physical fields. Among them, optoelectronic tweezers (OET) is a state-of-art technique that combines light stimuli with electric field together by leveraging the photoconductive effect of semiconductor materials. Herein, the behavior of micro-objects can be directly controlled by inducing the change of electric fields on demand in an optical manner. Relying on this light-induced electrokinetic effect, OET offers tremendous advantages in micromanipulation such as programmability, flexibility, versatility, high-throughput and ease of integration with other characterization systems, thus showing impressive performance compared to those of many other manipulation techniques. A lot of research on OET have been reported in recent years and the technology has developed rapidly in various fields of science and engineering. This work provides a comprehensive review of the OET technology, including its working mechanisms, experimental setups, applications in non-biological and biological scenarios, technology commercialization and future perspectives.
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