Structural and Functional Pulmonary Assessment in Severe COVID-19 Survivors at 12 Months after Discharge

Letter Infectious Diseases

Systemic consequences of COVID-19 infection in patients requiring mechanical ventilation: a 12-month prospective study

Marco Bongiovanni et al.

INFECTION (2023)

Article Anesthesiology

One-Year Multidisciplinary Follow-Up of Patients With COVID-19 Requiring Invasive Mechanical Ventilation

Alberto Zangrillo et al.

Summary: Patients with COVID-19 ARDS requiring invasive mechanical ventilation had good 1-year survival, quality of life, and functional recovery. Most patients reported no difficulties and showed overall good recovery.

JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA (2022)

添加到收藏夹

Article Radiology, Nuclear Medicine & Medical Imaging

CT Lung Abnormalities after COVID-19 at 3 Months and 1 Year after Hospital Discharge

Bavithra Vijayakumar et al.

Summary: COVID-19 survivors may experience persistent breathlessness and cough symptoms within 1 year after discharge. Chest CT scans showed persistent abnormalities in 56% of patients, with signs of fibrosis in a minority. Factors associated with more severe acute disease may contribute to CT abnormalities at 3-month follow-up.

RADIOLOGY (2022)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Severity of respiratory failure and computed chest tomography in acute COVID-19 correlates with pulmonary function and respiratory symptoms after infection with SARS-CoV-2: An observational longitudinal study over 12 months

Fridolin Steinbeis et al.

Summary: The severity of respiratory failure during COVID-19 is associated with the degree of pulmonary function impairment and respiratory quality of life in the year after acute infection.

RESPIRATORY MEDICINE (2022)

添加到收藏夹

Article Radiology, Nuclear Medicine & Medical Imaging

Chest CT Patterns from Diagnosis to 1 Year of Follow-up in Patients with COVID-19

Feng Pan et al.

Summary: This study assessed the chest CT manifestations of COVID-19 up to 1 year after symptom onset. The study found that 61% of patients had resolved CT abnormalities at 3 months and the number increased to 75% at 12 months. The risk factors for residual CT abnormalities at 1 year were age 50 or older, lymphopenia, and severe or aggravation of acute respiratory distress syndrome.

RADIOLOGY (2022)

添加到收藏夹

Article Primary Health Care

1-year radiological, functional and quality-of-life outcomes in patients with SARS-CoV-2 pneumonia-A prospective observational study

Marco Marando et al.

Summary: This study observed the condition of patients with SARS-CoV-2 pneumonia one year later and found that most patients still had abnormalities in radiological and functional aspects, and a decrease in health-related quality of life, despite showing progressive recovery.

NPJ PRIMARY CARE RESPIRATORY MEDICINE (2022)

添加到收藏夹

Article Medicine, General & Internal

Different Methods to Improve the Monitoring of Noninvasive Respiratory Support of Patients with Severe Pneumonia/ARDS Due to COVID-19: An Update

Paolo Pelosi et al.

Summary: The latest guidelines for the hospital care of patients with COVID-19-related acute respiratory failure recommend the use of noninvasive respiratory support (NIRS) instead of early intubation. Different clinical-radiological phenotypes of severe COVID-19 pneumonia have been categorized, which can benefit from the application of external positive end-expiratory pressure (PEEP) during noninvasive mechanical ventilation. Excessive negative pleural pressure swings (P-pl) can play a critical role in lung and diaphragm damage in patients treated with noninvasive respiratory support. Routine respiratory monitoring is necessary to prevent the worsening of respiratory condition and consider early initiation of invasive mechanical ventilation. Further research is needed to apply different monitoring methods in clinical practice and optimize ventilatory management for patients with acute respiratory distress syndrome due to SARS-CoV-2 infection.

JOURNAL OF CLINICAL MEDICINE (2022)

添加到收藏夹

Review Respiratory System

One-year follow-up CT findings in COVID-19 patients: A systematic review and meta-analysis

Atsuyuki Watanabe et al.

Summary: One year after recovery from COVID-19, some patients still have pulmonary abnormalities, especially fibrotic changes in severe/critical cases. These sequelae may persist for a longer time and require close observation and longer follow-up.

RESPIROLOGY (2022)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Association of COVID-19 With Major Arterial and Venous Thrombotic Diseases: A Population-Wide Cohort Study of 48 Million Adults in England and Wales

Rochelle Knight et al.

Summary: Incidence of vascular diseases remains elevated up to 49 weeks after COVID-19 diagnosis, with a faster decline for arterial thromboses than VTEs. Patients hospitalized with COVID-19, non-White individuals, and those without previous events are at higher risk. Policies to prevent severe COVID-19, including vaccination, early post-discharge review, risk factor control, and secondary preventive agents, are supported by these findings.

CIRCULATION (2022)

添加到收藏夹

Review Clinical Neurology

Cytokine Storm and Neuropathological Alterations in Patients with Neurological Manifestations of COVID-19

Christos Tsagkaris et al.

Summary: COVID-19 can cause neuroinflammation and potentially increase the risk of developing neurodegenerative diseases. Analysis of cytokines and biomarkers in cerebrospinal fluid can contribute to early detection, monitoring, and treatment of the neurological complications associated with the disease.

CURRENT ALZHEIMER RESEARCH (2022)

添加到收藏夹

Article Radiology, Nuclear Medicine & Medical Imaging

Follow-Up CT Patterns of Residual Lung Abnormalities in Severe COVID-19 Pneumonia Survivors: A Multicenter Retrospective Study

Giulia Besutti et al.

Summary: This study evaluated residual chest CT abnormalities in severe COVID-19 pneumonia survivors. Results showed that over 55% of patients had normal or barely normal follow-up CT scans, while non-fibrotic and fibrotic abnormalities were found in around 37.5% and 4.4% of patients respectively. Ground-glass opacities were the most common finding in non-fibrotic changes, while subpleural reticulation and traction bronchiectasis were frequent in fibrotic abnormalities. Residual abnormalities extension decreased over time in patients with multiple timepoints available.

TOMOGRAPHY (2022)

添加到收藏夹

Article Respiratory System

Prospective longitudinal evaluation of hospitalised COVID-19 survivors 3 and 12 months after discharge

Natalie Lorent et al.

Summary: COVID-19 survivors experienced limitations at 3 months, but showed improvement to almost complete recovery at 1 year. Factors such as female sex, pre-existing lung disease, smoking, and disease severity were related to poor functional recovery.

ERJ OPEN RESEARCH (2022)

添加到收藏夹

Article Respiratory System

One-year pulmonary impairment after severe COVID-19: a prospective, multicenter follow-up study

Paola Faverio et al.

Summary: This study investigated pulmonary sequelae in patients one year after hospitalization for SARS-CoV-2 pneumonia. The findings showed that DLCO impairment and non-fibrotic interstitial lung abnormalities were common, particularly in older patients requiring higher ventilatory support.

RESPIRATORY RESEARCH (2022)

添加到收藏夹

Article Respiratory System

Cardiopulmonary recovery after COVID-19: an observational prospective multicentre trial

Thomas Sonnweber et al.

Summary: A study found that some COVID-19 patients still experienced persistent symptoms and lung function impairment 100 days after the onset of the disease, but there was significant improvement in symptoms and cardiopulmonary status over time.

EUROPEAN RESPIRATORY JOURNAL (2021)

添加到收藏夹

Editorial Material Radiology, Nuclear Medicine & Medical Imaging

Interstitial Lung Disease after COVID-19 Infection: A Catalog of Uncertainties COMMENT

Athol U. Wells et al.

RADIOLOGY (2021)

添加到收藏夹

Article Radiology, Nuclear Medicine & Medical Imaging

Six-month Follow-up Chest CT Findings after Severe COVID-19 Pneumonia

Xiaoyu Han et al.

Summary: The study found that over one-third of severe COVID-19 patients showed fibrotic-like changes in the lung at 6-month follow-up CT, which were associated with older age, acute respiratory distress syndrome, longer hospital stays, tachycardia, noninvasive mechanical ventilation, and higher initial chest CT score.

RADIOLOGY (2021)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Health-related quality of life profiles, trajectories, persistent symptoms and pulmonary function one year after ICU discharge in invasively ventilated COVID-19 patients, a prospective follow-up study

Lorenzo Gamberini et al.

Summary: The study found that HRQoL among COVID-19 ICU survivors improved within one year after discharge, especially in the physical dimensions, while the mental dimensions and dyspnea remained stable. Four main 15D profiles were identified, with about 47.2% of patients achieving full recovery and about 58.4% experiencing persistent dyspnea.

RESPIRATORY MEDICINE (2021)

添加到收藏夹

Article Medicine, General & Internal

Follow-Up Study of the Chest CT Characteristics of COVID-19 Survivors Seven Months After Recovery

Mengqi Liu et al.

Summary: Most COVID-19 patients can absorb chest CT lesions without sequelae, but older patients with severe conditions are more likely to develop fibrosis, potentially leading to cardiopulmonary insufficiency. The combined clinical-radiological model may help predict the early formation of pulmonary fibrosis.

FRONTIERS IN MEDICINE (2021)

添加到收藏夹

Article Radiology, Nuclear Medicine & Medical Imaging

Post-discharge chest CT findings and pulmonary function tests in severe COVID-19 patients

Maurizio Balbi et al.

Summary: This study evaluated chest CT and PFT findings in severe COVID-19 patients after discharge, revealing that most survivors still had abnormal CT results about three months post-disease onset, with compromised lung volume correlated with PFT results. A small proportion of patients showed impaired diffusion capacity, possibly indicating pulmonary vasculopathy.

EUROPEAN JOURNAL OF RADIOLOGY (2021)

添加到收藏夹

Letter Infectious Diseases

COVID-19 mortality in Italy: The first wave was more severe and deadly, but only in Lombardy region

Francesco Chirico et al.

JOURNAL OF INFECTION (2021)

添加到收藏夹

Article Medicine, General & Internal

Assessment of Sequelae of COVID-19 Nearly 1 Year After Diagnosis

Fangyuan Zhou et al.

Summary: At nearly 1-year follow-up, COVID-19 survivors still had multi-system issues, including those in respiratory functioning, radiography, quality of life, and anxiety and depression. Non-severe cases also showed some sequelae, and the proportion of IgG negative cases in non-severe patients was higher than in severe cases. Conducting follow-ups and preventing SARS-CoV-2 reinfection in this group is necessary.

FRONTIERS IN MEDICINE (2021)

添加到收藏夹

Article Critical Care Medicine

3-month, 6-month, 9-month, and 12-month respiratory outcomes in patients following COVID-19-related hospitalisation: a prospective study

Xiaojun Wu et al.

Summary: Most patients recovering from severe COVID-19 showed improvement in dyspnoea scores and exercise capacity over time, but a subgroup of patients still exhibited persistent physiological and radiographic changes at 12 months post-discharge. A unified pathway for respiratory follow-up is needed for COVID-19 patients.

LANCET RESPIRATORY MEDICINE (2021)

添加到收藏夹

Article Medicine, General & Internal

One-year follow-up of chest CT findings in patients after SARS-CoV-2 infection

Yanfei Chen et al.

Summary: A 1-year follow-up study on COVID-19 patients after hospital discharge showed gradual recovery on chest CT scans. Residual abnormalities, mainly ground-glass opacity, were associated with older age, smoking, hypertension, lower oxygen saturation, and secondary bacterial infections. These abnormalities were correlated with reduced lung volume parameters.

BMC MEDICINE (2021)

添加到收藏夹

Letter Infectious Diseases

Follow-up study of pulmonary function among COVID-19 survivors 1 year after recovery

Xiquan Yan et al.

JOURNAL OF INFECTION (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Potential links between COVID-19-associated pulmonary aspergillosis and bronchiectasis as detected by high resolution computed tomography

Elisa Baratella et al.

Summary: This observational study aimed to highlight high resolution CT scan characteristics of COVID-19-associated pulmonary aspergillosis (CAPA), focusing on the detection of de-novo appeared or evolved bronchiectasis. The study included 19 CAPA patients, with a median age of 71.0, and found a high incidence of bronchiectasis. At a 6-month follow-up, the mortality rate for CAPA patients was over 60%.

FRONTIERS IN BIOSCIENCE-LANDMARK (2021)

添加到收藏夹

Article Medicine, General & Internal

Interstitial Lung Disease at High Resolution CT after SARS-CoV-2-Related Acute Respiratory Distress Syndrome According to Pulmonary Segmental Anatomy

Elisa Baratella et al.

Summary: This study evaluated HRCT findings in SARS-CoV-2-related ARDS survivors treated with prolonged low-dose methylprednisolone after discharge. The majority of patients showed alterations in pulmonary parenchyma on HRCT, with linear bands and ground glass opacities being the most common findings, symmetrically distributed with lower lobes most affected.

JOURNAL OF CLINICAL MEDICINE (2021)

添加到收藏夹

Article Radiology, Nuclear Medicine & Medical Imaging

Medium-term chest computed tomography (CT) follow-up of COVID-19 pneumonia patients after recovery to assess the rate of resolution and determine the potential predictors of persistent lung changes

Arshed Hussain Parry et al.

Summary: Nearly half of post-COVID-19 survivors showed residual lung abnormalities after >= 3 months of follow-up, with older age, higher comorbidities, longer hospital stay, more severe illness, and lower steroid usage being common characteristics among those with residual abnormalities. Certain clinico-radiological characteristics have the potential to identify individuals at risk of having residual lung abnormalities on medium-term follow-up.

EGYPTIAN JOURNAL OF RADIOLOGY AND NUCLEAR MEDICINE (2021)

添加到收藏夹

Article Radiology, Nuclear Medicine & Medical Imaging