期刊
GELS
卷 8, 期 10, 页码 -出版社
MDPI
DOI: 10.3390/gels8100609
关键词
hydrogels; photo-crosslinking; wound healing
资金
- National Natural Science Foundation of China [82172222]
- Outstanding Professional and Technical Leader Program of the Shanghai Municipal Science and Technology Commission [18XD1423700]
- Shanghai Health Industry Clinical Research Special Project [20204Y0443]
- Cross Research Project of Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine [JYJC202009]
- Shanghai Municipal Education Commission-Gaofeng Clinical Medicine Grant Support [20152227]
Wound healing is a complex physiological process, and the use of photo-crosslinking hydrogels can play an important role in improving its quality.
Wound healing is a dynamic physiological process, including three stages: inflammation, tissue formation, and remodeling. The quality of wound healing is affected by many topical and systemic factors, while any small factor may affect the process. Therefore, improving the quality of wound healing is a complex and arduous challenge. Photo-crosslinking reaction using visible light irradiation is a novel method for hydrogel preparation. Photo-crosslinking hydrogels can be controlled in time and space, and are not interfered by temperature conditions, which have been widely used in the fields of medicine and engineering. This review aims to summarize the application of photo-crosslinking hydrogels in improving the quality of wound healing, mainly including the material design, application mechanism, and effect of photo-crosslinking hydrogels applied in wound healing, followed by the applicable animal models for experimental research. Finally, this review analyzes the clinical application prospects of photo-crosslinking hydrogels in the field of wound healing.
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