Iridium tetrazolato complexes as efficient protein staining agents

In this work, three iridium(iii) tetrazolato complexes have been designed and successfully synthesized. Beside photophysical properties, their performances in protein staining have been comprehensively investigated in this work for the first time. Notably, these iridium(iii) tetrazolato complexes with high quantum efficiency exhibited much better protein staining properties than the commercial agent Coomassie Brilliant Blue (CBB) under the same experimental conditions, which may pave the way to explore new efficient iridium-based protein staining agents both for commercial markets and academic research in the future.

Automated summary

In this study, three iridium(iii) tetrazolato complexes were designed and synthesized, and their performance in protein staining was comprehensively investigated. These complexes exhibited better protein staining properties compared to the commercial agent Coomassie Brilliant Blue (CBB), paving the way for exploring new efficient iridium-based protein staining agents in both commercial markets and academic research in the future.