4.4 Review

Understanding the role of glycation in the pathology of various non-communicable diseases along with novel therapeutic strategies

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Food Science & Technology

Advanced glycation end products in food and their effects on intestinal tract

Chenzhipeng Nie et al.

Summary: With the improvement of living standards, harmful substances in diet have become a serious threat to people's health. Advanced glycation end products (AGEs) formed in processed food have been significantly associated with chronic diseases and sparked widespread controversy in academia. This review summarizes the factors influencing the production of dietary AGEs, their metabolism and absorption, and discusses their effects on intestinal health and gut microbiota.

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2022)

Article Cardiac & Cardiovascular Systems

Inhibitory effects of RAGE-aptamer on development of monocrotaline-induced pulmonary arterial hypertension in rats

Kazufumi Nakamura et al.

Summary: The study showed that continuous subcutaneous delivery of RAGE-aptamer suppresses monocrotaline-induced PAH in rats, reducing muscularization of small pulmonary arteries. These findings suggest that inhibition of RAGE could be a new therapeutic option for PAH.

JOURNAL OF CARDIOLOGY (2021)

Article Pharmacology & Pharmacy

Gliclazide alters macrophages polarization state in diabetic atherosclerosis in vitro via blocking AGE-RAGE/TLR4-reactive oxygen species-activated NF-kβ nexus

Humera Jahan et al.

Summary: The study demonstrated that Gliclazide retards diabetic atherosclerotic progression by altering macrophage M1 polarization state, inhibiting pro-inflammatory mediators, and promoting anti-inflammatory cytokines production.

EUROPEAN JOURNAL OF PHARMACOLOGY (2021)

Review Biochemistry & Molecular Biology

AGE/RAGE in diabetic kidney disease and ageing kidney

Xia-Qing Wu et al.

Summary: Diabetic kidney disease is a major cause of chronic kidney disease, and controlling blood glucose is effective in preventing it. However, the formation of AGEs related to high glucose plays a central role in the pathogenesis of DKD, causing oxidative stress and inflammation.

FREE RADICAL BIOLOGY AND MEDICINE (2021)

Review Medicine, Research & Experimental

Novel advances in inhibiting advanced glycation end product formation using natural compounds

Qinghe Song et al.

Summary: This paper discusses the formation, classification, and effects of AGEs on human health, with a focus on natural compounds as inhibitors of AGE formation. Major classes of natural inhibitors, including polyphenols, polysaccharides, terpenoids, vitamins, and alkaloids, have been described, with mechanisms of action ranging from scavenging free radicals to lowering blood glucose levels. These natural compounds, despite not being widely used clinically due to their low content levels, will be valuable in inspiring drug discovery.

BIOMEDICINE & PHARMACOTHERAPY (2021)

Article Biochemistry & Molecular Biology

Mechanistic insight into glycation inhibition of human serum albumin by vitamin B9: Multispectroscopic and molecular docking approach

Moshtak Ahmed Jaseem Al Jaseem et al.

Summary: The study revealed that folic acid showed significant effects in inhibiting glycation and reducing the formation of AGEs. The binding between folic acid and HSA is primarily stabilized by hydrophobic interaction and hydrogen bonding in the complex. Various experimental results confirmed the antiglycation activity of folic acid.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

Article Multidisciplinary Sciences

Deletion of RAGE fails to prevent hepatosteatosis in obese mice due to impairment of other AGEs receptors and detoxifying systems

Kristiaan Wouters et al.

Summary: Obesity-induced AGEs accumulation and RAGE expression lead to hepatosteatosis and inflammation in LeptrDb-/- mice. Despite genetic deletion of RAGE, intrahepatic AGEs remain high with impaired AGE-detoxifying system and sustained hepatosteatosis and inflammation. Targeting RAGE may not effectively prevent NAFLD in obese conditions due to direct liver specific crosstalk with other AGE-receptors and detoxifying systems.

SCIENTIFIC REPORTS (2021)

Article Biochemistry & Molecular Biology

The use of the soluble receptor for advanced glycation-end products (sRAGE) as a potential biomarker of disease risk and adverse outcomes

Jorge D. Erusalimsky

Summary: sRAGE, as a potential biomarker, may reflect disease risk and adverse outcomes, with high levels possibly related to overstimulation of cell surface RAGE among other factors.

REDOX BIOLOGY (2021)

Article Multidisciplinary Sciences

Advanced glycation end products and their receptors in serum of patients with type 2 diabetes

Diana Indyk et al.

Summary: This study discusses the role of Advanced Glycation End Products (AGEs) in patients with diabetes, including the determination of the concentrations of different AGEs and their receptors in serum samples, as well as the correlation with treatments such as metformin and aspirin. The results demonstrate the involvement of AGEs in the pathogenesis of diabetes and other degenerative diseases, highlighting the potential of AGEs as important diagnostic markers for disease progression and therapy effectiveness.

SCIENTIFIC REPORTS (2021)

Article Multidisciplinary Sciences

Glycation changes molecular organization and charge distribution in type I collagen fibrils

Sneha Bansode et al.

SCIENTIFIC REPORTS (2020)

Article Cardiac & Cardiovascular Systems

Basic Mechanisms of Diabetic Heart Disease

Rebecca H. Ritchie et al.

CIRCULATION RESEARCH (2020)

Article Orthopedics

RAGE-dependent NF-kB inflammation processes in the capsule of frozen shoulders

Toshihisa Yano et al.

JOURNAL OF SHOULDER AND ELBOW SURGERY (2020)

Article Dentistry, Oral Surgery & Medicine

Effect of vitamin C and E on oxidative stress and antioxidant system in the salivary glands of STZ-induced diabetic rats

Flavia Kazue Ibuki et al.

ARCHIVES OF ORAL BIOLOGY (2020)

Article Multidisciplinary Sciences

Circulating antibodies against age-modified proteins in patients with coronary atherosclerosis

Edina Korca et al.

SCIENTIFIC REPORTS (2020)

Review Biochemistry & Molecular Biology

Impact of advanced glycation end products (AGEs) signaling in coronary artery disease

Marinos Kosmopoulos et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2019)

Article Biochemistry & Molecular Biology

Thioredoxin system as a gatekeeper in caspase-6 activation and nuclear lamina integrity: Implications for Alzheimer's disease

Md Imamul Islam et al.

FREE RADICAL BIOLOGY AND MEDICINE (2019)

Review Cell Biology

AGE-RAGE stress: a changing landscape in pathology and treatment of Alzheimer's disease

Kailash Prasad

MOLECULAR AND CELLULAR BIOCHEMISTRY (2019)

Review Biochemistry & Molecular Biology

Glycation-induced modification of tissue-specific ECM proteins: A pathophysiological mechanism in degenerative diseases

Sneha B. Bansode et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2019)

Review Cell Biology

Dietary advanced glycation end products and their relevance for human health

Kerstin Nowotny et al.

AGEING RESEARCH REVIEWS (2018)

Article Biochemistry & Molecular Biology

sRAGE prolonged stem cell survival and suppressed RAGE-related inflammatory cell and T lymphocyte accumulations in an Alzheimer's disease model

Seyeon Oh et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)

Review Medicine, Research & Experimental

Nitric oxide bioavailability dysfunction involves in atherosclerosis

Jing-yi Chen et al.

BIOMEDICINE & PHARMACOTHERAPY (2018)

Article Integrative & Complementary Medicine

(R)-α-Lipoic acid inhibits fructose-induced myoglobin fructation and the formation of advanced glycation end products (AGEs) in vitro

Hardik Ghelani et al.

BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE (2018)

Review Cardiac & Cardiovascular Systems

Diabetes, Hypertension, and Cardiovascular Disease: Clinical Insights and Vascular Mechanisms

John R. Petrie et al.

CANADIAN JOURNAL OF CARDIOLOGY (2018)

Article Pharmacology & Pharmacy

Production and application of HMGB1 derived recombinant RAGE-antagonist peptide for anti-inflammatory therapy in acute lung injury

Seonyeong Lee et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2018)

Article Genetics & Heredity

RAGE may act as a tumour suppressor to regulate lung cancer development

Shuangshuang Wu et al.

Review Biochemistry & Molecular Biology

Diabetic Retinopathy: Pathophysiology and Treatments

Wei Wang et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Review Oncology

An insight on the association of glycation with hepatocellular carcinoma

Nasimudeen R. Jabir et al.

SEMINARS IN CANCER BIOLOGY (2018)

Review Oncology

The receptor for advanced glycation end products: A fuel to pancreatic cancer

Uzma Shahab et al.

SEMINARS IN CANCER BIOLOGY (2018)

Review Oncology

Do all roads lead to the Rome? The glycation perspective!

Saheem Ahmad et al.

SEMINARS IN CANCER BIOLOGY (2018)

Review Oncology

AGEs, RAGEs and s-RAGE; friend or foe for cancer

Saheem Ahmad et al.

SEMINARS IN CANCER BIOLOGY (2018)

Article Biochemistry & Molecular Biology

Preparation and evaluation of anti-renal fibrosis activity of novel truncated TGF- receptor type II

Haifeng Liu et al.

BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY (2018)

Review Biochemistry & Molecular Biology

Targeting TGF-β Signaling in Kidney Fibrosis

Yoshitaka Isaka

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Review Geriatrics & Gerontology

Glycation Damage: A Possible Hub for Major Pathophysiological Disorders and Aging

Maxime Fournet et al.

AGING AND DISEASE (2018)

Review Biochemistry & Molecular Biology

Obesity and inflammation

Jacek Karczewski et al.

EUROPEAN CYTOKINE NETWORK (2018)

Article Cell Biology

Role of endothelial-to-mesenchymal transition induced by TGF-β1 in transplant kidney interstitial fibrosis

Zijie Wang et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2017)

Review Food Science & Technology

Polyphenols with antiglycation activity and mechanisms of action: A review of recent findings

Wan-Ju Yeh et al.

JOURNAL OF FOOD AND DRUG ANALYSIS (2017)

Article Food Science & Technology

Dietary advanced glycation end products modify gut microbial composition and partially increase colon permeability in rats

Wanting Qu et al.

MOLECULAR NUTRITION & FOOD RESEARCH (2017)

Article Multidisciplinary Sciences

RAGE inhibition reduces acute lung injury in mice

Raiko Blondonnet et al.

SCIENTIFIC REPORTS (2017)

Article Gastroenterology & Hepatology

Repeated Oral Exposure to N ε-Carboxymethyllysine, a Maillard Reaction Product, Alleviates Gut Microbiota Dysbiosis in Colitic Mice

Nesreen ALJahdali et al.

DIGESTIVE DISEASES AND SCIENCES (2017)

Article Biochemistry & Molecular Biology

Inhibitory effect of vitamin B3 against glycation and reactive oxygen species production in HSA: An in vitro approach

K. M. Abdullah et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2017)

Review Biochemistry & Molecular Biology

Introduction to the human gut microbiota

Elizabeth Thursby et al.

BIOCHEMICAL JOURNAL (2017)

Article Biochemistry & Molecular Biology

Pentamidine blocks the interaction between mutant S100A5 and RAGE V domain and inhibits the RAGE signaling pathway

Ching Chang Cho et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)

Article Biochemistry & Molecular Biology

Cellular mechanisms and consequences of glycation in atherosclerosis and obesity

Raquel Lopez-Diez et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2016)

Article Pharmacology & Pharmacy

Diabetes and Complications: Cellular Signaling Pathways, Current Understanding and Targeted Therapies

Krishna A. Adeshara et al.

CURRENT DRUG TARGETS (2016)

Review Pharmacology & Pharmacy

Advanced Glycation End Products: Association with the Pathogenesis of Diseases and the Current Therapeutic Advances

Thekkuttuparambil A. Ajith et al.

CURRENT CLINICAL PHARMACOLOGY (2016)

Review Cell Biology

Oxidative Stress and Adipocyte Biology: Focus on the Role of AGEs

Florence Boyer et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2015)

Article Gastroenterology & Hepatology

Diet and the Intestinal Microbiome: Associations, Functions, and Implications for Health and Disease

Lindsey G. Albenberg et al.

GASTROENTEROLOGY (2014)

Review Biochemistry & Molecular Biology

Glycoxidation of biological macromolecules: A critical approach to halt the menace of glycation

Saheem Ahmad et al.

GLYCOBIOLOGY (2014)

Article Gastroenterology & Hepatology

Microbiota and diabetes: an evolving relationship

Herbert Tilg et al.

Review Biotechnology & Applied Microbiology

Role of Methylglyoxal in Alzheimer's Disease

Cristina Angeloni et al.

BIOMED RESEARCH INTERNATIONAL (2014)

Review Biochemistry & Molecular Biology

Role of advanced glycation end products in cellular signaling

Christiane Ott et al.

REDOX BIOLOGY (2014)

Review Immunology

The Renin-Angiotensin-Aldosterone System in Vascular Inflammation and Remodeling

Maricica Pacurari et al.

INTERNATIONAL JOURNAL OF INFLAMMATION (2014)

Review Endocrinology & Metabolism

Molecular mechanisms of AGE/RAGE-mediated fibrosis in the diabetic heart

Jia Zhao et al.

WORLD JOURNAL OF DIABETES (2014)

Article Biochemistry & Molecular Biology

Uptake of advanced glycation end products by proximal tubule epithelial cells via macropinocytosis

Marisa A. Gallicchio et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2013)

Article Integrative & Complementary Medicine

Proanthocyanidin Attenuation of Oxidative Stress and NF-κB Protects Apolipoprotein E-Deficient Mice against Diabetic Nephropathy

Abdulrahman L. Al-Malki et al.

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2013)

Article Medicine, Research & Experimental

Inhibitory effect of soluble RAGE in disturbed flow-induced atherogenesis

Chang Hoon Ha et al.

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2013)

Article Chemistry, Medicinal

The effects of aminoguanidine on retinopathy in STZ-induced diabetic rats

Dawei Luo et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)

Review Medicine, Research & Experimental

TGF-β - an excellent servant but a bad master

Lenka Kubiczkova et al.

JOURNAL OF TRANSLATIONAL MEDICINE (2012)

Article Geriatrics & Gerontology

AGEs induce Alzheimer-like tau pathology and memory deficit via RAGE-mediated GSK-3 activation

Xiao-Hong Li et al.

NEUROBIOLOGY OF AGING (2012)

Article Multidisciplinary Sciences

Oral advanced glycation endproducts (AGEs) promote insulin resistance and diabetes by depleting the antioxidant defenses AGE receptor-1 and sirtuin 1

Weijing Cai et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Endocrinology & Metabolism

Fibronectin glycation increases IGF-I induced proliferation of human aortic smooth muscle cells

Maria Lucia Correa-Giannella et al.

DIABETOLOGY & METABOLIC SYNDROME (2012)

Review Biochemistry & Molecular Biology

A novel improved therapy strategy for diabetic nephropathy Targeting AGEs

Xuemei Zhou et al.

ORGANOGENESIS (2012)

Article Urology & Nephrology

Vascular Remodeling and Arterial Calcification Are Directly Mediated by S100A12 (EN-RAGE) in Chronic Kidney Disease

Joseph Gawdzik et al.

AMERICAN JOURNAL OF NEPHROLOGY (2011)

Article Endocrinology & Metabolism

Receptor for AGE (RAGE): signaling mechanisms in the pathogenesis of diabetes and its complications

Ravichandran Ramasamy et al.

YEAR IN DIABETES AND OBESITY (2011)

Article Pharmacology & Pharmacy

Inhibition of advanced glycation end products by aminoguanidine restores mast cell numbers and reactivity in alloxan-diabetic rats

Vinicius F. Carvalho et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2011)

Review Biochemistry & Molecular Biology

Inflammation, Oxidative Stress, and Obesity

Alba Fernandez-Sanchez et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2011)

Article Biochemistry & Molecular Biology

Effects of atorvastatin on progression of diabetic nephropathy and local RAGE and soluble RAGE expressions in rats

Lin Lu et al.

JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B (2011)

Review Biochemistry & Molecular Biology

RAGE: The beneficial and deleterious effects by diverse mechanisms of actions

Sun-Ho Han et al.

MOLECULES AND CELLS (2011)

Review Geriatrics & Gerontology

Advanced glycation endproducts and their receptor RAGE in Alzheimer's disease

Velandai Srikanth et al.

NEUROBIOLOGY OF AGING (2011)

Article Biochemistry & Molecular Biology

Advanced glycation end products enhance amyloid precursor protein expression by inducing reactive oxygen species

Shun-Yao Ko et al.

FREE RADICAL BIOLOGY AND MEDICINE (2010)

Article Multidisciplinary Sciences

Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa

Carlotta De Filippo et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Review Medicine, Research & Experimental

RAGE (Receptor for Advanced Glycation Endproducts), RAGE Ligands, and their role in Cancer and Inflammation

Louis J. Sparvero et al.

JOURNAL OF TRANSLATIONAL MEDICINE (2009)

Article Cell Biology

Oxidative stress in Alzheimer disease

Alejandro Gella et al.

CELL ADHESION & MIGRATION (2009)

Article Cardiac & Cardiovascular Systems

Effects of Inhibition of AGE-RAGE Interaction in Pressure-Overload Hypertrophy by Treatment with sRAGE

Catalin F. Baicu et al.

JOURNAL OF CARDIAC FAILURE (2008)

Article Immunology

RAGE signaling sustains inflammation and promotes tumor development

Christoffer Gebhardt et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2008)

Review Pharmacology & Pharmacy

Diabetic neuropathy: Mechanisms to management

James L. Edwards et al.

PHARMACOLOGY & THERAPEUTICS (2008)

Article Endocrinology & Metabolism

Pathology and pathogenetic mechanisms of diabetic neuropathy: Correlation with clinical signs and symptoms

Soroku Yagihashi et al.

DIABETES RESEARCH AND CLINICAL PRACTICE (2007)

Review Cardiac & Cardiovascular Systems

Advanced glycation end products - Sparking the development of diabetic vascular injury

Alison Goldin et al.

CIRCULATION (2006)

Article Biochemistry & Molecular Biology

Disordered osteoclast formation in RAGE-deficient mouse establishes an essential role for RAGE in diabetes related bone loss

KH Ding et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)

Review Medical Laboratory Technology

Glycation endproducts in osteoporosis - Is there a pathophysiologic importance?

Gert E. Hein

CLINICA CHIMICA ACTA (2006)

Review Food Science & Technology

Metabolism of Maillard reaction products by the human gut microbiota - implications for health

Kieran M. Tuohy et al.

MOLECULAR NUTRITION & FOOD RESEARCH (2006)

Review Endocrinology & Metabolism

Advanced glycation endproducts - role in pathology of diabetic complications

N Ahmed

DIABETES RESEARCH AND CLINICAL PRACTICE (2005)

Article Hematology

Morphologic findings of coronary atherosclerotic plaques in diabetics - A postmortem study

AP Burke et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2004)

Article Biochemistry & Molecular Biology

Reversibility of established diabetic glomerulopathy by anti-TGF-β antibodies in dbldb mice

S Chen et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)

Review Biochemistry & Molecular Biology

Use of aminoguanidine (Pimagedine) to prevent the formation of advanced glycation endproducts

PJ Thornalley

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2003)

Article Geriatrics & Gerontology

Increased protein glycation in cerebrospinal fluid of Alzheimer's disease

VV Shuvaev et al.

NEUROBIOLOGY OF AGING (2001)

Article Endocrinology & Metabolism

Influence of nonenzymatic glycation on biomechanical properties of cortical bone

D Vashishth et al.

Review Endocrinology & Metabolism

Advanced glycation end-products: a review

R Singh et al.

DIABETOLOGIA (2001)