New Method for the Synthesis of Phenylglyoxal Derivatives

The paper proposes a new one-pot ozonolytic synthesis of acylhydrazones from phenylacrolein acetals, which includes ozonolytic cleavage of the substrate in methanol and treatment of the intermediate peroxides with hydrazides of capric, nicotinic, isonicotinic, benzoic, and para-hydroxybenzoic acids taken in excess.

Automated summary

The paper proposes a new one-pot ozonolytic synthesis of acylhydrazones from phenylacrolein acetals, using ozonolytic cleavage and treatment with various hydrazides.