☆ 4.3 Review

Epidemiology of Gram-negative bacteria during coronavirus disease 2019. What is the real pandemic?

CURRENT OPINION IN INFECTIOUS DISEASES (2022)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Public, Environmental & Occupational Health

Unexpected benefit of COVID-19 hospital restrictions: Reduction in patients isolating with multidrug resistant organisms after restrictions were lifted

Thomas M. Elliott et al.

Summary: During the COVID-19 pandemic, measures to prevent microorganism transmission were implemented in hospitals. A study conducted in Queensland, Australia found that patient isolation days reduced during COVID restrictions and increased again post-COVID restrictions, but did not return to pre-COVID levels. The study also concluded that heightened infection control measures effectively prevented common hospital-acquired MRO infections.

INFECTION DISEASE & HEALTH (2022)

添加到收藏夹

Article Infectious Diseases

The changing pattern of bacterial and fungal respiratory isolates in patients with and without COVID-19 admitted to intensive care unit

Gianluca Zuglian et al.

Summary: During the COVID-19 pandemic, there have been changes in the microbiological flora of ICUs, with an increase in the prevalence of certain bacteria and a decrease in others. The overuse of antimicrobial therapy in COVID-19 patients has also affected the resistance profiles of bacteria.

BMC INFECTIOUS DISEASES (2022)

添加到收藏夹

Review Infectious Diseases

Predictors and microbiology of respiratory and bloodstream bacterial infection in patients with COVID-19: living rapid review update and meta-regression

Bradley J. Langford et al.

Summary: Analysis of 171 studies revealed a 5.1% prevalence of bacterial co-infection and a 13.1% prevalence of secondary infection in patients with COVID-19. Factors such as ICU setting and mechanical ventilation were associated with higher risk of bacterial infection.

CLINICAL MICROBIOLOGY AND INFECTION (2022)

添加到收藏夹

Article Critical Care Medicine

Increased Incidence of Ventilator-Acquired Pneumonia in Coronavirus Disease 2019 Patients: A Multicentric Cohort Study*

Charles-Herve Vacheron et al.

Summary: This study found a higher incidence of ventilator-associated pneumonia among COVID-19 patients compared to the general ICU population. The microbiological ecology and resistance pattern were similar between the two groups, except for a lower rate of methicillin-resistant Staphylococcus aureus in the COVID-19 exposed patients.

CRITICAL CARE MEDICINE (2022)

添加到收藏夹

Review Infectious Diseases

Methicillin-resistant Staphylococcus aureus lung infection in coronavirus disease 2019: how common?

Matteo Bassetti et al.

Summary: The burden of MRSA lung infection in patients with COVID-19 remains unclear due to heterogeneity in studies, but MRSA is among the most common causative agents of pulmonary infection in COVID-19 patients.

CURRENT OPINION IN INFECTIOUS DISEASES (2022)

添加到收藏夹

Article Infectious Diseases

Surging bloodstream infections and antimicrobial resistance during the first wave of COVID-19: a study in a large multihospital institution in the Paris region

Rishma Amarsy et al.

Summary: This study measured the impact of the first wave of COVID-19 on the incidence of bloodstream infections at the largest multisite public healthcare institution in France. The results showed that the COVID-19 pandemic had a strong impact on hospital management and had unfavorable effects on severe infections, antimicrobial resistance, and laboratory work diagnostics.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2022)

添加到收藏夹

Article Public, Environmental & Occupational Health

Trend analysis of carbapenem-resistant Gram-negative bacteria and antimicrobial consumption in the post- COVID-19 era: an extra challenge for healthcare institutions

V. M. de Carvalho Hessel Dias et al.

Summary: This study analyzed the incidence density trend of carbapenem-resistant Gram-negative bacteria and antimicrobial consumption in 99 critical care facilities in a low/middle-income country. The findings showed an increase in the incidence density of carbapenem-resistant Acinetobacter baumannii (CRAB) in 2020, which was strongly correlated with the incidence density of COVID-19. There was also an increase in polymyxin consumption in 2020, but it was not significantly correlated with CRAB or COVID-19 incidence density, likely due to empirical and untargeted prescribing.

JOURNAL OF HOSPITAL INFECTION (2022)

添加到收藏夹

Review Critical Care Medicine

Microbiology Assessments in Critically Ill Patients

Adrian John Brink et al.

Summary: The prevalence of infections in critically ill patients is high, and appropriate microbiological assessment is crucial for diagnostic and therapeutic decisions. Conventional microbiology follows best practice procedures, but rapid and panel-based diagnostic strategies show promise in improving healthcare. However, more rigorous evaluation and intervention studies are needed before widespread adoption. These diagnostics may supplement, but not replace, conventional microbiological assessments.

SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE (2022)

添加到收藏夹

Review Public, Environmental & Occupational Health

The challenge of preventing and containing outbreaks of multidrug-resistant organisms and Candida auris during the coronavirus disease 2019 pandemic: report of a carbapenem-resistant Acinetobacter baumannii outbreak and a systematic review of the literature

Reto Thoma et al.

Summary: During the COVID-19 pandemic, hospitals have experienced outbreaks of multidrug-resistant organisms (MDRO), mainly caused by CRAB and C. auris. Inadequate adherence to personal protective equipment/hand hygiene, PPE shortage, and high antibiotic use were the most commonly reported potentially modifiable factors contributing to these outbreaks.

ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL (2022)

添加到收藏夹

Article Public, Environmental & Occupational Health

Carbapenem-resistant bacteria in an intensive care unit during the coronavirus disease 2019 (COVID-19) pandemic: A multicenter before-and-after cross-sectional study

Renato Pascale et al.

Summary: This study assessed the incidence of colonization and infection with CPE and CR-Ab in ICUs before and during the COVID-19 pandemic. The results showed no significant change in CPE colonization and infection, but a significant increase in CR-Ab colonization and infection. The CR-Ab strains belonged to the same clonal lineage and horizontal transmission was observed. Therefore, infection control activities should be conducted during the pandemic and adjusted according to the situation.

INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY (2022)

添加到收藏夹

Review Public, Environmental & Occupational Health

Rising rates of hospital-onset Klebsiella spp. and Pseudomonas aeruginosa bacteraemia in NHS acute trusts in England: a review of national surveillance data, August 2020-February 2021

R. Sloot et al.

Summary: Hospital-onset Klebsiella spp. and Pseudomonas aeruginosa bacteraemia rates in England reached the highest levels since mandatory surveillance began in April 2017, with incidence rates higher than the average rates in the previous three years. These trends were accompanied by an increase in the percentage of hospital-onset bacteraemia cases also positive for severe acute respiratory syndrome coronavirus-2.

JOURNAL OF HOSPITAL INFECTION (2022)

添加到收藏夹

Article Immunology

Evaluation of bacterial agents isolated from endotracheal aspirate cultures of Covid-19 general intensive care patients and their antibiotic resistance profiles compared to pre-pandemic conditions

Omer Acer et al.

Summary: This study analyzed the bacteria isolated from endotracheal aspirate cultures of Covid-19 patients in the intensive care unit and compared the antibiotic resistance profiles with the pre-pandemic period. The findings showed an increase in antibiotic resistance among common bacterial agents and a higher mortality rate among Covid-19 patients.

MICROBIAL PATHOGENESIS (2022)

添加到收藏夹

Review Immunology

The Collateral Effects of COVID-19 Pandemic on the Status of Carbapenemase-Producing Pathogens

Carole Ayoub Moubareck et al.

Summary: The serious challenge of antimicrobial resistance continues to threaten public health in the era of COVID-19. The pandemic has fostered antimicrobial resistance, possibly due to high use of antibiotics, increased use of biocides, and disruption of proper healthcare. Gram-negative bacteria producing carbapenemases have been causing secondary infections in COVID-19 patients, with evidence accumulating worldwide. The resilience and limited treatment options for carbapenemases raise concerns during the pandemic.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2022)

添加到收藏夹

Article Public, Environmental & Occupational Health

Blood culture utilization and epidemiology of antimicrobial-resistant bloodstream infections before and during the COVID-19 pandemic in the Indonesian national referral hospital

Robert Sinto et al.

Summary: The incidence and etiology of antimicrobial-resistant bloodstream infections were similar between COVID-19 and non-COVID-19 cases in an Indonesian national referral hospital. The incidence rates of hospital-origin antimicrobial-resistant bloodstream infections increased in 2020, likely due to increased blood culture utilization.

ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL (2022)

添加到收藏夹

Article Infectious Diseases

An Observational Study of MDR Hospital-Acquired Infections and Antibiotic Use during COVID-19 Pandemic: A Call for Antimicrobial Stewardship Programs

Nour Shbaklo et al.

Summary: The COVID-19 pandemic has led to major adjustments in healthcare systems and has caused an increase in multidrug-resistant (MDR) hospital-acquired infections (HAIs) at Molinette Hospital. The study also found changes in antibiotic consumption, with a reduction in fluoroquinolone use and an increase in the use of fourth- and fifth-generation cephalosporins and piperacillin-tazobactam during the COVID-19 period. The findings highlight the need for improved infection control practices and microbiological diagnosis during pandemics.

ANTIBIOTICS-BASEL (2022)

添加到收藏夹

Article Public, Environmental & Occupational Health

The impact of the COVID-19 pandemic on healthcare acquired infections with multidrug resistant organisms

Jennifer Cole et al.

Summary: The study found that the COVID-19 pandemic has led to increased compliance with infection prevention measures among healthcare workers. Initiatives promoting infection prevention among healthcare workers have raised awareness of effective hand washing, equipment cleaning, and proper use of personal protective equipment, resulting in a decrease in healthcare-acquired infections with multidrug-resistant organisms.

AMERICAN JOURNAL OF INFECTION CONTROL (2021)

添加到收藏夹

Article Immunology

Empiric Antibacterial Therapy and Community-onset Bacterial Coinfection in Patients Hospitalized With Coronavirus Disease 2019 (COVID-19): A Multi-hospital Cohort Study

Valerie M. Vaughn et al.

Summary: Among 1705 hospitalized COVID-19 patients, 56.6% received early empiric antibacterial therapy, while only 3.5% had confirmed community-onset bacterial infections. The use of early empiric antibacterials varied widely across hospitals.

CLINICAL INFECTIOUS DISEASES (2021)

添加到收藏夹

Review Infectious Diseases

Antibiotic prescribing in patients with COVID-19: rapid review and meta-analysis

Bradley J. Langford et al.

Summary: The study estimated that approximately three-quarters of patients with COVID-19 receive antibiotic treatment, which is significantly higher than the estimated prevalence of bacterial co-infection. This suggests a potential for high rates of unnecessary antibiotic use in patients with COVID-19.

CLINICAL MICROBIOLOGY AND INFECTION (2021)

添加到收藏夹

Article Infectious Diseases

Effect of the Normalized Epidemic Prevention and Control Requirements on hospital-acquired and community-acquired infections in China

Caiyun Chen et al.

Summary: This study found that the new prevention and control requirements implemented during the COVID-19 pandemic had significant effects on community-acquired infections (CAIs) but not on hospital-acquired infections (HAIs).

BMC INFECTIOUS DISEASES (2021)

添加到收藏夹

Article Public, Environmental & Occupational Health

Change in hospital antibiotic use and acquisition of multidrug-resistant gram-negative organisms after the onset of coronavirus disease 2019

Jacqueline T. Bork et al.

Summary: Interrupted time series segmented regression analysis was conducted in an academic hospital to study the trends of antibiotic use and multidrug-resistant gram-negative (MDRGN) acquisition relative to COVID-19. Antibiotic use, particularly related to pneumonia, increased significantly after the onset of COVID-19 compared to the same period in 2019. Additionally, MDRGN acquisition showed a 3% increase for every rise in positive COVID-19 tests per week.

INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY (2021)

添加到收藏夹

Article Medicine, General & Internal

Protective effect of SARS-CoV-2 preventive measures against ESKAPE and Escherichia coli infections

Rita Gaspari et al.

Summary: The study suggests that strict adherence to hygiene measures and human contact restrictions during the COVID-19 pandemic may reduce the transmission of ESKAPEEc pathogens.

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2021)

添加到收藏夹

Article Infectious Diseases

A multicenter analysis of the clinical microbiology and antimicrobial usage in hospitalized patients in the US with or without COVID-19

Laura Puzniak et al.

Summary: There are differences in pathogens, antimicrobial usage, and healthcare utilization between hospitalized COVID-19 patients and non-COVID-19 patients in the US. Despite similar rates of non-COVID-19 pathogens, COVID-19 patients have higher rates of hospital-onset infections and antimicrobial usage, as well as longer hospital stays.

BMC INFECTIOUS DISEASES (2021)

添加到收藏夹

Review Infectious Diseases

SARS-CoV-2 and immune-microbiome interactions: Lessons from respiratory viral infections

Farhan Cyprian et al.

Summary: By the beginning of 2020, COVID-19 caused by SARS-CoV-2 had become a global pandemic, mainly spread through the respiratory system and associated with various chronic diseases. Recent studies suggest that the pulmonary and gut microbiomes may modulate the course of COVID-19.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2021)

添加到收藏夹

Editorial Material Public, Environmental & Occupational Health

Impact of SARS CoV-2 pandemic on carbapenemase-producing Klebsiella pneumoniae prevention and control programme: convergent or divergent action?

V. Belvisi et al.

JOURNAL OF HOSPITAL INFECTION (2021)

添加到收藏夹

Article Immunology

SARS-CoV-2-Indigenous Microbiota Nexus: Does Gut Microbiota Contribute to Inflammation and Disease Severity in COVID-19?

Indranil Chattopadhyay et al.

Summary: Research suggests that alterations in gut microbiome may play a crucial role in determining the clinical outcome of COVID-19 patients. Manipulating gut microbiota could lead to the development of effective therapeutic strategies against the immunopathogenesis and comorbidities of COVID-19.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2021)

添加到收藏夹

Article Public, Environmental & Occupational Health

Unintended consequences of infection prevention and control measures during COVID-19 pandemic

Liang En Ian Wee et al.

Summary: The study evaluated the impact of a multimodal IPC strategy for COVID-19 containment on hospital-acquired infections. Enhanced IPC measures successfully contained health care-associated respiratory-viral infections (HA-RVI) rates. MRSA acquisition and central-line-associated bloodstream infection rates declined significantly, while rates of other HAIs remained stable.

AMERICAN JOURNAL OF INFECTION CONTROL (2021)

添加到收藏夹

Review Immunology

Role of Gut Microbiome in COVID-19: An Insight Into Pathogenesis and Therapeutic Potential

Ikram Hussain et al.

Summary: COVID-19, caused by SARS-CoV-2, has led to a global crisis with potential multi-organ dysfunction. Alterations in the gut microbiome may be related to disease progression by causing intestinal permeability and exacerbating inflammation.

FRONTIERS IN IMMUNOLOGY (2021)

添加到收藏夹

Review Critical Care Medicine

The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity

Marcin F. Osuchowski et al.

Summary: The zoonotic SARS-CoV-2 virus causing COVID-19 has devastating consequences worldwide, affecting primarily the respiratory system but also leading to long-term complications. Understanding the pathophysiology and immune response of COVID-19 is crucial for optimizing patient care and treatment strategies.

LANCET RESPIRATORY MEDICINE (2021)

添加到收藏夹

Review Medicine, General & Internal

Carbapenem-Resistant Klebsiella pneumoniae Infections in ICU COVID-19 Patients-A Scoping Review

Wioletta Medrzycka-Dabrowska et al.

Summary: The study highlights the importance of paying attention to carbapenem-resistant Klebsiella pneumoniae infections in patients with COVID-19. Rational antibiotic therapy should be used to prevent the increase of bacterial resistance, along with continuous monitoring and surveillance of hospital infections caused by multidrug-resistant organisms.

JOURNAL OF CLINICAL MEDICINE (2021)

添加到收藏夹

Review Infectious Diseases

Identification of bacterial co-detections in COVID-19 critically Ill patients by BioFire® FilmArray® pneumonia panel: a systematic review and meta-analysis

Tristan T. Timbrook et al.

Summary: The BioFire(R) FilmArray (R) Pneumonia Panel plays a significant role in detecting bacteria and clinical management in critically ill COVID-19 patients, reducing turnaround time for identification and improving accuracy in antimicrobial use for clinicians.

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE (2021)

添加到收藏夹

Article Infectious Diseases

Impact of the COVID-19 pandemic on the surveillance, prevention and control of antimicrobial resistance: a global survey

Sara Tomczyk et al.

Summary: The survey on the global impact of COVID-19 on AMR among GLASS countries revealed reduced availability of healthcare and cleaning staff, which could bias AMR surveillance data. Additionally, most countries still lack complete data to measure the specific impact of COVID-19 on AMR rates.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2021)

添加到收藏夹

Article Microbiology

Secondary bacterial infections and antimicrobial resistance in COVID-19: comparative evaluation of pre-pandemic and pandemic-era, a retrospective single center study

Mustafa Karatas et al.

Summary: The study aimed to evaluate the epidemiology and antimicrobial resistance patterns of bacterial pathogens in COVID-19 patients and compared them with control groups from pre-pandemic and pandemic era. The results showed a lower frequency of secondary bacterial infections in COVID-19 patients, indicating a need for more careful and targeted antimicrobial prescription. Additionally, there were differences in the etiology and antimicrobial resistance patterns of bacterial infections in COVID-19 patients compared to pre-pandemic and pandemic era control groups.

ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS (2021)

添加到收藏夹

Article Immunology

Effect of Inadequate Empiric Antibacterial Therapy on Hospital Outcomes in SARS-CoV-2-Positive and -Negative US Patients With a Positive Bacterial Culture: A Multicenter Evaluation From March to November 2020

Laura Puzniak et al.

Summary: This study evaluated hospital outcomes based on the adequacy of antibacterial therapy for bacterial pathogens in US patients during the COVID-19 pandemic. Inadequate empiric therapy was associated with higher odds of mortality and increased hospital length of stay for patients with positive bacterial cultures, highlighting the importance of timely and appropriate therapeutic management.

OPEN FORUM INFECTIOUS DISEASES (2021)

添加到收藏夹

Article Infectious Diseases

The Impact of COVID-19 on the Profile of Hospital-Acquired Infections in Adult Intensive Care Units

Aleksa Despotovic et al.

Summary: Hospital-acquired infections (HAIs) continue to be a global public health concern, especially with the ongoing COVID-19 pandemic. The study revealed high rates of antimicrobial resistance, particularly in COVID-19 patients, with Acinetobacter spp. being a dominant cause of HAIs. Urgent approval of new drugs and rigorous surveillance are needed to address the alarming resistance rates.

ANTIBIOTICS-BASEL (2021)

添加到收藏夹

Review Respiratory System

The role of co-infections and secondary infections in patients with COVID-19

Charles Feldman et al.

Summary: The current review provides an extensive look at the prevalence of co-infections and superinfections in patients with COVID-19, highlighting their potential impact on the severity and outcome of the disease. However, a clear distinction between the two types of infections is often lacking in the literature.

PNEUMONIA (2021)

添加到收藏夹

Editorial Material Medicine, Research & Experimental

SARS-CoV-2, bacterial co-infections, andAMR: the deadly trio inCOVID-19?

Jose A. Bengoechea et al.

EMBO MOLECULAR MEDICINE (2020)

添加到收藏夹

Letter Public, Environmental & Occupational Health

Multi-drug-resistant infections in the COVID-19 era: a framework for considering the potential impact

D. Dona et al.

JOURNAL OF HOSPITAL INFECTION (2020)

添加到收藏夹

Review Infectious Diseases

Bacterial co-infection and secondary infection in patients with COVID-19: a living rapid review and meta-analysis

Bradley J. Langford et al.

CLINICAL MICROBIOLOGY AND INFECTION (2020)

添加到收藏夹

Article Medicine, General & Internal

Antimicrobial Stewardship Program, COVID-19, and Infection Control: Spread of Carbapenem-Resistant Klebsiella Pneumoniae Colonization in ICU COVID-19 Patients. What Did Not Work?

Beatrice Tiri et al.

JOURNAL OF CLINICAL MEDICINE (2020)

添加到收藏夹

Review Critical Care Medicine

Antimicrobial resistance in ICUs: an update in the light of the COVID-19 pandemic

Rafael Canton et al.

CURRENT OPINION IN CRITICAL CARE (2020)

添加到收藏夹

Article Immunology

External Validation of Difficult-to-Treat Resistance Prevalence and Mortality Risk in Gram-Negative Bloodstream Infection Using Electronic Health Record Data From 140 US Hospitals

Sameer S. Kadri et al.

OPEN FORUM INFECTIOUS DISEASES (2019)

添加到收藏夹

Article Microbiology

The Microbiology of Bloodstream Infection: 20-Year Trends from the SENTRY Antimicrobial Surveillance Program

Daniel J. Diekema et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2019)

添加到收藏夹

Article Immunology

Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society

Andre C. Kalil et al.

CLINICAL INFECTIOUS DISEASES (2016)

添加到收藏夹

Review Infectious Diseases

The frequency of influenza and bacterial coinfection: a systematic review and meta-analysis

Eili Y. Klein et al.

INFLUENZA AND OTHER RESPIRATORY VIRUSES (2016)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.