期刊
COMPLEMENTARY THERAPIES IN MEDICINE
卷 23, 期 2, 页码 149-156出版社
CHURCHILL LIVINGSTONE
DOI: 10.1016/j.ctim.2015.01.011
关键词
Osteopathic; manipulative treatment; Headache; Pain; Sham therapy; Disability; Drug; HIT-6
Objective: To assess the effectiveness of OMT on chronic migraineurs using HIT-6 questionnaire, drug consumption, days of migraine, pain intensity and functional disability. Design: 3-Armed randomized controlled trial setting: all patients admitted in the Department of Neurology of Ancona's United Hospitals, Italy, with a diagnosis of migraine and without chronic illness, were considered eligible for the study. Interventions: Patients were randomly divided into three groups: (1) OMT + medication therapy, (2) sham + medication therapy and (3) medication therapy only. Patients received 8 treatments in a study period of 6 months. Main outcome measures: Changing from baseline HIT-6 score. Results: 105 subjects were included. At the end of the study, ANOVA showed that OMT significantly reduced HIT-6 score (mean change scores OMT conventional care: -8.74; 95% confidence interval (CI) -12.96 to -4.52; p < 0.001 and OMT sham: -6.62; 95% CI -10.85 to -2.41; p < 0.001), drug consumption (OMT sham: RR = 0.22, 95% CI 0.11-0.40; OMT control: RR = 0.20, 95% CI 0.10-0.36), days of migraine (OMT-conventional care: M = -21.06; 95% CI -23.19 to -18.92; p < 0.001 and OMT sham: -17.43; 95% CI -19.57 to -15.29; p < 0.001), pain intensity (OMT sham: RR = 0.42, 95% CI -0.24-0.69; OMT control: RR = 0.31, 95% CI 0.19-0.49) and functional disability (p < 0.001). Conclusions: These findings suggest that OMT may be considered a valid procedure for the management of migraineurs. (C) 2015 Elsevier Ltd. All rights reserved.
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