期刊
GENES
卷 7, 期 9, 页码 -出版社
MDPI
DOI: 10.3390/genes7090064
关键词
telomerase; telomere; H; ACA ribonucleoprotein; small nucleolar RNA; small Cajal body RNA; spliceosome; exosome
资金
- Canadian Institute for Health Research [MOP133449]
- Chercheur National of the Fonds de la Recherche en Sante du Quebec (FRSQ)
- CIHR Canada Graduate Scholarships-Master's Program
- Cole Foundation
- Lady Davis Institute/TD Bank Studentship Award
The vast body of literature regarding human telomere maintenance is a true testament to the importance of understanding telomere regulation in both normal and diseased states. In this review, our goal was simple: tell the telomerase story from the biogenesis of its parts to its maturity as a complex and function at its site of action, emphasizing new developments and how they contribute to the foundational knowledge of telomerase and telomere biology.
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