相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Mechanism and regulation of DNA end resection in eukaryotes
Lorraine S. Symington
CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY (2016)
RECQL5 has unique strand annealing properties relative to the other human RecQ helicase proteins
Prabhat Khadka et al.
DNA REPAIR (2016)
Essential Roles for Polymerase θ-Mediated End Joining in the Repair of Chromosome Breaks
David W. Wyatt et al.
MOLECULAR CELL (2016)
A role for human homologous recombination factors in suppressing microhomology-mediated end joining
Sara Ahrabi et al.
NUCLEIC ACIDS RESEARCH (2016)
Ligase I and ligase III mediate the DNA double-strand break ligation in alternative end-joining
Guangqing Lu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Redundant function of DNA ligase 1 and 3 in alternative end-joining during immunoglobulin class switch recombination
Shahnaz Masani et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Polq-Mediated End Joining Is Essential for Surviving DNA Double-Strand Breaks during Early Zebrafish Development (vol 15, pg 707, 2016)
Summer B. Thyme et al.
CELL REPORTS (2016)
Polymerase θ is a robust terminal transferase that oscillates between three different mechanisms during end-joining
Tatiana Kent et al.
ELIFE (2016)
Human DNA polymerase α in binary complex with a DNA:DNA template-primer
Javier Coloma et al.
SCIENTIFIC REPORTS (2016)
Replication-induced DNA damage after PARP inhibition causes G2 delay, and cell line-dependent apoptosis, necrosis and multinucleation
Idun Dale Rein et al.
CELL CYCLE (2015)
Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair
Raphael Ceccaldi et al.
NATURE (2015)
Mammalian polymerase θ promotes alternative NHEJ and suppresses recombination
Pedro A. Mateos-Gomez et al.
NATURE (2015)
A mechanism for the suppression of homologous recombination in G1 cells
Alexandre Orthwein et al.
NATURE (2015)
Human DNA polymerase θ grasps the primer terminus to mediate DNA repair
Karl E. Zahn et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ
Tatiana Kent et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
Primase-polymerases are a functionally diverse superfamily of replication and repair enzymes
Thomas A. Guilliam et al.
NUCLEIC ACIDS RESEARCH (2015)
Human RECQ1 helicase-driven DNA unwinding, annealing, and branch migration: Insights from DNA complex structures
Ashley C. W. Pike et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
DNA polymerases δ and λ cooperate in repairing double-strand breaks by microhomology-mediated end-joining in Saccharomyces cerevisiae
Damon Meyer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Structural mechanisms of DNA binding and unwinding in bacterial RecQ helicases
Kelly A. Manthei et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Structure of the Helicase Domain of DNA Polymerase Theta Reveals a Possible Role in the Microhomology-Mediated End-Joining Pathway
Joseph A. Newman et al.
STRUCTURE (2015)
Human DNA polymerase θ grasps the primer terminus to mediate DNA repair
Karl E. Zahn et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ
Tatiana Kent et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
DNA double-strand break repair pathway choice and cancer
Tomas Aparicio et al.
DNA REPAIR (2014)
A Role for DNA Polymerase θ in Promoting Replication through Oxidative DNA Lesion, Thymine Glycol, in Human Cells
Jung-Hoon Yoon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Chromosomal Translocations in Human Cells Are Generated by Canonical Nonhomologous End-Joining
Hind Ghezraoui et al.
MOLECULAR CELL (2014)
Sae2 promotes dsDNA endonuclease activity within Mre11-Rad50-Xrs2 to resect DNA breaks
Elda Cannavo et al.
NATURE (2014)
RPA antagonizes microhomology-mediated repair of DNA double-strand breaks
Sarah K. Deng et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2014)
A role for DNA polymerase θ in the timing of DNA replication
Anne Fernandez-Vidal et al.
NATURE COMMUNICATIONS (2014)
A Polymerase Theta-dependent repair pathway suppresses extensive genomic instability at endogenous G4 DNA sites
Wouter Koole et al.
NATURE COMMUNICATIONS (2014)
Mechanism of Suppression of Chromosomal Instability by DNA Polymerase POLQ
Matthew J. Yousefzadeh et al.
PLOS GENETICS (2014)
Modernizing the Nonhomologous End-Joining Repertoire: Alternative and Classical NHEJ Share the Stage
Ludovic Deriano et al.
ANNUAL REVIEW OF GENETICS, VOL 47 (2013)
HELQ promotes RAD51 paralogue-dependent repair to avert germ cell loss and tumorigenesis
Carrie A. Adelman et al.
NATURE (2013)
Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells
Lan N. Truong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Human DNA helicase HELQ participates in DNA interstrand crosslink tolerance with ATR and RAD51 paralogs
Kei-ichi Takata et al.
NATURE COMMUNICATIONS (2013)
Inhibition of Homologous Recombination by the PCNA-Interacting Protein PARI
George-Lucian Moldovan et al.
MOLECULAR CELL (2012)
Unwinding and Rewinding: Double Faces of Helicase?
Yuliang Wu
JOURNAL OF NUCLEIC ACIDS (2012)
Physical interaction between archaeal DNA repair helicase Hel308 and Replication Protein A (RPA)
Isabel L. Woodman et al.
DNA REPAIR (2011)
Human HEL308 Localizes to Damaged Replication Forks and Unwinds Lagging Strand Structures
Agnieszka A. Tafel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Lesion Bypass Activity of DNA Polymerase θ (POLQ) Is an Intrinsic Property of the Pol Domain and Depends on Unique Sequence Inserts
Matthew Hogg et al.
JOURNAL OF MOLECULAR BIOLOGY (2011)
CtIP promotes microhomology-mediated alternative end joining during class-switch recombination
Mieun Lee-Theilen et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)
An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathway
Yu Zhang et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)
DNA Ligase III Promotes Alternative Nonhomologous End-Joining during Chromosomal Translocation Formation
Deniz Simsek et al.
PLOS GENETICS (2011)
A Small Interfering RNA Screen of Genes Involved in DNA Repair Identifies Tumor-Specific Radiosensitization by POLQ Knockdown
Geoff S. Higgins et al.
CANCER RESEARCH (2010)
SF1 and SF2 helicases: family matters
Margaret E. Fairman-Williams et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2010)
DNA polymerases ν and θ are required for efficient immunoglobulin V gene diversification in chicken
Masaoki Kohzaki et al.
JOURNAL OF CELL BIOLOGY (2010)
Purified human BRCA2 stimulates RAD51-mediated recombination
Ryan B. Jensen et al.
NATURE (2010)
Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis
Mary Ellen Moynahan et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
The alternative end-joining pathway for repair of DNA double-strand breaks requires PARP1 but is not dependent upon microhomologies
Wael Y. Mansour et al.
NUCLEIC ACIDS RESEARCH (2010)
Dual Roles for DNA Polymerase Theta in Alternative End-Joining Repair of Double-Strand Breaks in Drosophila
Sze Ham Chan et al.
PLOS GENETICS (2010)
Roles for NBS1 in Alternative Nonhomologous End-Joining of V(D)J Recombination Intermediates
Ludovic Deriano et al.
MOLECULAR CELL (2009)
Role of mammalian Mre11 in classical and alternative nonhomologous end joining
Anyong Xie et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)
Human DNA polymerase θ possesses 5-dRP lyase activity and functions in single-nucleotide base excision repair in vitro
Rajendra Prasad et al.
NUCLEIC ACIDS RESEARCH (2009)
Lack of DNA Polymerase θ (POLQ) Radiosensitizes Bone Marrow Stromal Cells In Vitro and Increases Reticulocyte Micronuclei after Total-Body Irradiation
Julie P. Goff et al.
RADIATION RESEARCH (2009)
Caenorhabditis elegans POLQ-1 and HEL-308 function in two distinct DNA interstrand cross-link repair pathways
Diego M. Muzzini et al.
DNA REPAIR (2008)
DNA polymerase theta (POLQ) can extend from mismatches and from bases opposite a (6-4) photoproduct
Mineaki Seki et al.
DNA REPAIR (2008)
FANCJ helicase defective in Fanconia anemia and breast cancer unwinds G-quadruplex DNA to defend genomic stability
Yuliang Wu et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Regulation of DNA repair throughout the cell cycle
Dana Branzei et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Non-hexameric DNA helicases and translocases: mechanisms and regulation
Timothy M. Lohman et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
HARP Is an ATP-Driven Annealing Helicase
Timur Yusufzai et al.
SCIENCE (2008)
Structure of the DNA repair helicase Hel308 reveals DNA binding and autoinhibitory domains
Jodi D. Richards et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Regulation of DNA double-strand break repair pathway choice
Meena Shrivastav et al.
CELL RESEARCH (2008)
RECQL5/Recql5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filaments
Yiduo Hu et al.
GENES & DEVELOPMENT (2007)
Novel pro- and anti-recombination activities of the Bloom's syndrome helicase
Dmitry V. Bugreev et al.
GENES & DEVELOPMENT (2007)
Rag mutations reveal robust alternative end joining
Barbara Corneo et al.
NATURE (2007)
IgH class switching and translocations use a robust non-classical end-joining pathway
Catherine T. Yan et al.
NATURE (2007)
Structural basis for DNA duplex separation by a superfamily-2 helicase
Katharina Buettner et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)
DNA polymerases η and θ function in the same genetic pathway to generate mutations at A/T during somatic hypermutation of Ig genes
Keiji Masuda et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways
Minli Wang et al.
NUCLEIC ACIDS RESEARCH (2006)
Vertebrate POLQ and POLβ cooperate in base excision repair of oxidative DNA damage
Michio Yoshimura et al.
MOLECULAR CELL (2006)
DNA polymerase θ contributes to the generation of C/G mutations during somatic hypermutation of Ig genes
K Masuda et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
New mammalian cellular systems to study mutations introduced at the break site by non-homologous end-joining
P Rebuzzini et al.
DNA REPAIR (2005)
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
HE Bryant et al.
NATURE (2005)
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
H Farmer et al.
NATURE (2005)
Archaeal Hel308 helicase targets replication forks in vivo and in vitro and unwinds lagging strands
CP Guy et al.
NUCLEIC ACIDS RESEARCH (2005)
Involvement of poly(ADP-ribose) polymerase-1 and XRCC1/DNA ligase III in an alternative route for DNA double-strand breaks rejoining
M Audebert et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The mouse genomic instability mutation chaos1 is an allele of Polq that exhibits genetic interaction with Atm
N Shima et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
High-efficiency bypass of DNA damage by human DNA polymerase Q
M Seki et al.
EMBO JOURNAL (2004)
The Srs2 helicase prevents recombination by disrupting Rad51 nucleoprotein filaments
X Veaute et al.
NATURE (2003)
DNA helicase Srs2 disrupts the Rad51 presynaptic filament
L Krejci et al.
NATURE (2003)
POLQ (Pol theta), a DNA polymerase and DNA-dependent ATPase in human cells
M Seki et al.
NUCLEIC ACIDS RESEARCH (2003)