4.7 Review

Dual-Acting Compounds Targeting Endocannabinoid and Endovanilloid Systems-A Novel Treatment Option for Chronic Pain Management

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Chemistry, Medicinal

Arylboronic acids as dual-action FAAH and TRPV1 ligands

Enrico Morera et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2016)

Article Chemistry, Medicinal

TRPV1-FAAH-COX: The Couples Game in Pain Treatment

Francesca Aiello et al.

CHEMMEDCHEM (2016)

Article Chemistry, Medicinal

Potent multitarget FAAH-COX inhibitors: Design and structure-activity relationship studies

Marco Migliore et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2016)

Article Pharmacology & Pharmacy

The multiplicity of spinal AA-5-HT anti-nociceptive action in a rat model of neuropathic pain

Natalia Malek et al.

PHARMACOLOGICAL RESEARCH (2016)

Article Immunology

Endocannabinoids drive the acquisition of an alternative phenotype in microglia

M. Mecha et al.

BRAIN BEHAVIOR AND IMMUNITY (2015)

Review Chemistry, Medicinal

Transient receptor potential vanilloid type 1 antagonists: a patent review (2011-2014)

Yoonji Lee et al.

EXPERT OPINION ON THERAPEUTIC PATENTS (2015)

Review Pharmacology & Pharmacy

Polypharmacology Shakes Hands with Complex Aetiopathology

James S. Brodie et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2015)

Correction Neurosciences

Peripheral gating of pain signals by endogenous lipid mediators (vol 17, pg 164, 2014)

Daniele Piomelli et al.

NATURE NEUROSCIENCE (2014)

Article Chemistry, Medicinal

Tetrahydro-β-carboline derivatives targeting fatty acid amide hydrolase (FAAH) and transient receptor potential (TRP) channels

Giorgio Ortar et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2013)

Article Biochemistry & Molecular Biology

Rationally Designed Multitarget Agents Against Inflammation and Pain

S. H. Hwang et al.

CURRENT MEDICINAL CHEMISTRY (2013)

Review Pharmacology & Pharmacy

Non-psychotropic analgesic drugs from the endocannabinoid system: Magic bullet or multiple-target strategies?

Katarzyna Starowicz et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2013)

Review Pharmacology & Pharmacy

Regulation of mu-Opioid Receptors: Desensitization, Phosphorylation, Internalization, and Tolerance

John T. Williams et al.

PHARMACOLOGICAL REVIEWS (2013)

Review Biochemistry & Molecular Biology

Redundancy of Endocannabinoid Inactivation: New Challenges and Opportunities for Pain Control

Fabiana Piscitelli et al.

ACS CHEMICAL NEUROSCIENCE (2012)

Article Neurosciences

Fatty Acid Amide Hydrolase Inhibitors – Progress and Potential

Ish K. Khanna et al.

CNS & Neurological Disorders-Drug Targets (2012)

Letter Rheumatology

Safety Advantages of Topical versus Oral Nonsteroidal Antiinflammatory Drugs

Roy D. Altman

JOURNAL OF RHEUMATOLOGY (2011)

Editorial Material Anesthesiology

A FAAH-fetched approach to treat osteoarthritis pain

Aron H. Lichtman et al.

Editorial Material Medicine, General & Internal

NSAIDs and risk of lower gastrointestinal bleeding

Elham Rahme et al.

LANCET (2010)

Article Pharmacology & Pharmacy

Regulation of Inflammatory Pain by Inhibition of Fatty Acid Amide Hydrolase

Pattipati S. Naidu et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2010)

Review Clinical Neurology

Multifunctional Drugs: A Novel Concept for Psychopharmacology

Stephen M. Stahl

CNS SPECTRUMS (2009)

Article Pharmacology & Pharmacy

Blockade of Endocannabinoid-Degrading Enzymes Attenuates Neuropathic Pain

S. G. Kinsey et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2009)

Review Pharmacology & Pharmacy

Lipids as targets for novel anti-inflammatory therapies

Andrea Huwiler et al.

PHARMACOLOGY & THERAPEUTICS (2009)

Article Multidisciplinary Sciences

Spinal Endocannabinoids and CB1 Receptors Mediate C-Fiber-Induced Heterosynaptic Pain Sensitization

Alejandro J. Pernia-Andrade et al.

SCIENCE (2009)

Review Rehabilitation

Chronic pain and opiates: balancing pain control and risks in long-term opioid treatment

Rollin M. Gallagher et al.

ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION (2008)

Editorial Material Pharmacology & Pharmacy

A physiological role for endocannabinoid-derived products of cyclooxygenase-2-mediated oxidative metabolism

J. Guindon et al.

BRITISH JOURNAL OF PHARMACOLOGY (2008)

Review Chemistry, Multidisciplinary

Enzymatic pathways that regulate endocannabinoid signaling in the nervous system

Kay Ahn et al.

CHEMICAL REVIEWS (2008)

Review Pharmacology & Pharmacy

The contribution of cyclooxygenase-2 to endocannabinoid metabolism and action

C. J. Fowler

BRITISH JOURNAL OF PHARMACOLOGY (2007)

Review Pharmacology & Pharmacy

Endocannabinoid metabolism and uptake: novel targets for neuropathic and inflammatory pain

M. D. Jhaveri et al.

BRITISH JOURNAL OF PHARMACOLOGY (2007)

Article Chemistry, Medicinal

New N-arachidonoylserotonin analogues with potential dual mechanism of action against pain

Giorgio Ortar et al.

JOURNAL OF MEDICINAL CHEMISTRY (2007)

Article Gastroenterology & Hepatology

Risk of peptic ulcer hospitalizations in users of NSAIDs with gastroprotective cotherapy versus coxibs

Wayne A. Ray et al.

GASTROENTEROLOGY (2007)

Review Biochemistry & Molecular Biology

Endocannabinoids and the regulation of their levels in health and disease

Vincenzo Di Marzo et al.

CURRENT OPINION IN LIPIDOLOGY (2007)

Article Pharmacology & Pharmacy

Inhibition of fatty acid amide hydrolase produces analgesia by multiple mechanisms

Leon Chang et al.

BRITISH JOURNAL OF PHARMACOLOGY (2006)

Article Neurosciences

Analgesic effects of fatty acid amide hydrolase inhibition in a rat model of neuropathic pain

Maulik D. Jhaveri et al.

JOURNAL OF NEUROSCIENCE (2006)

Article Pharmacology & Pharmacy

The potency of the fatty acid amide hydrolase inhibitor URB597 is dependent upon the assay pH

Ben Paylor et al.

PHARMACOLOGICAL RESEARCH (2006)

Review Cell Biology

The TRPV1 receptor and nociception

David C. Immke et al.

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2006)

Article Pharmacology & Pharmacy

Actions of the FAAH inhibitor URB597 in neuropathic and inflammatory chronic pain models

A Jayamanne et al.

BRITISH JOURNAL OF PHARMACOLOGY (2006)

Article Biochemistry & Molecular Biology

Anandamide acts as an intracellular messenger amplifying Ca2+ influx via TRPV1 channels

M van der Stelt et al.

EMBO JOURNAL (2005)

Article Gastroenterology & Hepatology

Fatty acid amide hydrolase controls mouse intestinal motility in vivo

R Capasso et al.

GASTROENTEROLOGY (2005)

Article Pharmacology & Pharmacy

Reversible inhibitors of fatty acid amide hydrolase that promote analgesia: Evidence for an unprecedented combination of potency and selectivity

AH Lichtman et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2004)

Article Biochemistry & Molecular Biology

Inhibition of fatty acid amidohydrolase, the enzyme responsible for the metabolism of the endocannabinoid anandamide, by analogues of arachidonoyl-serotonin

CJ Fowler et al.

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2003)

Review Pharmacology & Pharmacy

Fatty acid amide hydrolase, an enzyme with many bioactive substrates. Possible therapeutic implications

T Bisogno et al.

CURRENT PHARMACEUTICAL DESIGN (2002)

Article Pharmacology & Pharmacy

Neurobehavioral activity in mice of N-vanillyl-arachidonyl-amide

V Di Marzo et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2000)

Article Multidisciplinary Sciences

Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia

JB Davis et al.

NATURE (2000)