期刊
ORGANIC & BIOMOLECULAR CHEMISTRY
卷 20, 期 48, 页码 9746-9752出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/d2ob02006h
关键词
-
A simple and efficient method for the synthesis of N1-substituted-4-nitropyrazole-5-carboxylates has been developed, with excellent regioselectivity and good yields.
A simple and expeditious method for the regioselective synthesis of N1-substituted-4-nitropyrazole-5-carboxylates was developed. The method involves cyclocondensation of ethyl 4-(dimethylamino)-3-nitro-2-oxobut-3-enoate with a series of monosubstituted hydrazines to give N1-substituted-4-nitropyrazole-5-carboxylates with excellent regioselectivity and good yields. Solvent effects on regioselectivity of the cyclocondensation were examined.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据