4.5 Article

An Amyloid-Like Pathological Conformation of TDP-43 Is Stabilized by Hypercooperative Hydrogen Bonds

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

The TDP-43 N-terminal domain structure at high resolution

Miguel Mompean et al.

FEBS JOURNAL (2016)

Article Chemistry, Physical

Complex System Assembly Underlies a Two-Tiered Model of Highly Delocalized Electrons

Miguel Mompean et al.

JOURNAL OF PHYSICAL CHEMISTRY LETTERS (2016)

Editorial Material Biochemistry & Molecular Biology

Electrostatic Repulsion Governs TDP-43 C-terminal Domain Aggregation

Miguel Mompean et al.

PLOS BIOLOGY (2016)

Article Neurosciences

Key Points Concerning Amyloid Infectivity and Prion-Like Neuronal Invasion

Alba Espargaro et al.

FRONTIERS IN MOLECULAR NEUROSCIENCE (2016)

Article Multidisciplinary Sciences

Mass spectrometric analysis of accumulated TDP-43 in amyotrophic lateral sclerosis brains

Fuyuki Kametani et al.

SCIENTIFIC REPORTS (2016)

Article Biochemistry & Molecular Biology

A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation

Avinash Patel et al.

Article Chemistry, Physical

Structural Evidence of Amyloid Fibril Formation in the Putative Aggregation Domain of TDP-43

Miguel Mompean et al.

JOURNAL OF PHYSICAL CHEMISTRY LETTERS (2015)

Article Biochemistry & Molecular Biology

Structural characterization of the minimal segment of TDP-43 competent for aggregation

Miguel Mompean et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2014)

Article Biochemistry & Molecular Biology

An ALS-mutant TDP-43 neurotoxic peptide adopts an anti-parallel β-structure and induces TDP-43 redistribution

Li Zhu et al.

HUMAN MOLECULAR GENETICS (2014)

Article Chemistry, Multidisciplinary

Self-Assembling Properties of Peptides Derived from TDP-43 C-Terminal Fragment

Akash Saini et al.

LANGMUIR (2014)

Article Multidisciplinary Sciences

TDP-43 N terminus encodes a novel ubiquitin-like fold and its unfolded form in equilibrium that can be shifted by binding to ssDNA

Haina Qin et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Clinical Neurology

TDP-43 skeins show properties of amyloid in a subset of ALS cases

John L. Robinson et al.

ACTA NEUROPATHOLOGICA (2013)

Article Biochemistry & Molecular Biology

The dual functions of the extreme N-terminus of TDP-43 in regulating its biological activity and inclusion formation

Yong-Jie Zhang et al.

HUMAN MOLECULAR GENETICS (2013)

Article Biochemistry & Molecular Biology

Structural Transformation of the Amyloidogenic Core Region of TDP-43 Protein Initiates Its Aggregation and Cytoplasmic Inclusion

Lei-Lei Jiang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Biochemistry & Molecular Biology

The Truncated C-terminal RNA Recognition Motif of TDP-43 Protein Plays a Key Role in Forming Proteinaceous Aggregates

Yi-Ting Wang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Biochemistry & Molecular Biology

Molecular basis of UG-rich RNA recognition by the human splicing factor TDP-43

Peter J. Lukavsky et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2013)

Article Cell Biology

Prion-like Properties of Pathological TDP-43 Aggregates from Diseased Brains

Takashi Nonaka et al.

CELL REPORTS (2013)

Article Biochemistry & Molecular Biology

Cellular Model of TAR DNA-binding Protein 43 (TDP-43) Aggregation Based on Its C-terminal Gln/Asn-rich Region

Mauricio Budini et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Review Biochemistry & Molecular Biology

TDP-43: gumming up neurons through protein-protein and protein-RNA interactions

Emanuele Buratti et al.

TRENDS IN BIOCHEMICAL SCIENCES (2012)

Letter Clinical Neurology

A harmonized classification system for FTLD-TDP pathology

Ian R. A. Mackenzie et al.

ACTA NEUROPATHOLOGICA (2011)

Article Biochemistry & Molecular Biology

Delineation of the Core Aggregation Sequences of TDP-43 C-Terminal Fragment

Akash Saini et al.

CHEMBIOCHEM (2011)

Article Biochemistry & Molecular Biology

Regulation of TDP-43 aggregation by phosphorylation andp62/SQSTM1

Owen A. Brady et al.

JOURNAL OF NEUROCHEMISTRY (2011)

Article Medicine, General & Internal

Amyotrophic lateral sclerosis

Matthew C. Kiernan et al.

LANCET (2011)

Article Neurosciences

Characterizing the RNA targets and position-dependent splicing regulation by TDP-43

James R. Tollervey et al.

NATURE NEUROSCIENCE (2011)

Article Biochemistry & Molecular Biology

An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity

Weirui Guo et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)

Article Multidisciplinary Sciences

Hyperphosphorylation as a Defense Mechanism to Reduce TDP-43 Aggregation

Huei-Ying Li et al.

PLOS ONE (2011)

Article Biochemistry & Molecular Biology

Interaction with Polyglutamine Aggregates Reveals a Q/N-rich Domain in TDP-43

Rodrigo A. Fuentealba et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Chemistry, Multidisciplinary

Induction of Amyloid Fibrils by the C-Terminal Fragments of TDP-43 in Amyotrophic Lateral Sclerosis

Allan K. -H. Chen et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)

Article Biochemistry & Molecular Biology

Identification of casein kinase-1 phosphorylation sites on TDP-43

Fuyuki Kametani et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)

Review Biochemistry & Molecular Biology

Mutations in TDP-43 link glycine-rich domain functions to amyotrophic lateral sclerosis

G. Scott Pesiridis et al.

HUMAN MOLECULAR GENETICS (2009)

Article Biochemistry & Molecular Biology

Structural insights into TDP-43 in nucleic-acid binding and domain interactions

Pan-Hsien Kuo et al.

NUCLEIC ACIDS RESEARCH (2009)

Article Clinical Neurology

Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

Masato Hasegawa et al.

ANNALS OF NEUROLOGY (2008)

Article Clinical Neurology

Fine structural analysis of the neuronal inclusions of frontotemporal lobar degeneration with TDP-43 proteinopathy

Julian R. Thorpe et al.

JOURNAL OF NEURAL TRANSMISSION (2008)

Article Multidisciplinary Sciences

A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDR-43 aggregation and cellular toxicity

Brian S. Johnson et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Pathology

TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions

Nigel J. Cairns et al.

AMERICAN JOURNAL OF PATHOLOGY (2007)

Article Biochemistry & Molecular Biology

TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

Tetsuaki Arai et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)

Article Multidisciplinary Sciences

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

Manuela Neumann et al.

SCIENCE (2006)

Article Biochemistry & Molecular Biology

Human, Drosophila, and C-elegans TDP43:: Nucleic acid binding properties and splicing regulatory function

YM Ayala et al.

JOURNAL OF MOLECULAR BIOLOGY (2005)