Polyclonal Dissemination of OXA-232 Carbapenemase- Producing Klebsiella pneumoniae, France, 2013-2021

Article Infectious Diseases

Characteristics and outcomes of carbapenemase harbouring carbapenem-resistant Klebsiella spp. bloodstream infections: a multicentre prospective cohort study in an OXA-48 endemic setting

Burcu Isler et al.

Summary: This study investigated carbapenem-resistant Klebsiella spp. bloodstream infections in Turkey and found important findings such as the prevalence of different types of carbapenemases and factors associated with mortality rates.

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES (2022)

添加到收藏夹

Article Microbiology

OXA-181-Like Carbapenemases in Klebsiella pneumoniae ST14, ST15, ST23, ST48, and ST231 from Septicemic Neonates: Coexistence with NDM-5, Resistome, Transmissibility, and Genome Diversity

Sharmi Naha et al.

Summary: This study characterized carbapenemase-producing isolates in an Indian neonatal unit in terms of their resistome, transmissibility, and genome diversity. It identified diverse sequence types and highlighted the extent of plasmid transmission across different strains. The study also found the coexistence of different carbapenemase genes in these neonatal isolates, emphasizing the need for prompt attention to neonatal health care in the face of antimicrobial resistance.

MSPHERE (2021)

添加到收藏夹

Article Infectious Diseases

Emergence and genomics of OXA-232-producing Klebsiella pneumoniae in a hospital in Yancheng, China

Zhichen Zhu et al.

Summary: This study investigated the phylogenetic relationship and composition of antimicrobial resistance genes (ARGs) in OXA-232-producing Klebsiella pneumoniae (OXA232Kp) strains from a Chinese hospital. The three ST15-OXA232Kp strains formed a distinct subgroup in phylogenetic analysis. They shared identical ARG composition and genetic background, indicating clonal dissemination of multiple ARGs in this hospital setting. Further surveillance and study are recommended to prevent the spread of OXA232Kp strains in China.

JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE (2021)

添加到收藏夹

Article Infectious Diseases

Optical DNA Mapping of Plasmids Reveals Clonal Spread of Carbapenem-Resistant Klebsiella pneumoniae in a Large Thai Hospital

Sriram Kk et al.

Summary: In this study, 27 CR-KP isolates from 16 patients were analyzed using NGS and ODM, with most isolates belonging to ST16. The plasmid carrying the bla(NDM-1) gene was identified in the ST16 isolates, and the potential of using ODM of plasmids as a marker for bacterial spread was highlighted. Additionally, ODM was able to differentiate between plasmids carrying different resistance genes in the ST16 isolates.

ANTIBIOTICS-BASEL (2021)

添加到收藏夹

Review Microbiology